Results 31 to 40 of about 1,170,895 (233)

Integration of disease-specific single nucleotide polymorphisms, expression quantitative trait loci and coexpression networks reveal novel candidate genes for type 2 diabetes. [PDF]

, 2012
Aims/hypothesisWhile genome-wide association studies (GWASs) have been successful in identifying novel variants associated with various diseases, it has been much more difficult to determine the biological mechanisms underlying these associations ...
Butte, AJ, Chen, R, Corona, E, Kang, HP, Schadt, EE, Yang, X, Zhang, B   +6 more
core   +2 more sources

Host association and selection on salivary protein genes in bed bugs and related blood-feeding ectoparasites [PDF]

Royal Society Open Science, 2017
Reciprocal selective pressures can drive coevolutionary changes in parasites and hosts, and result in parasites that are highly specialized to their hosts.
Benoit Talbot, Ondřej Balvín, Maarten J. Vonhof, Hugh G. Broders, Brock Fenton, Nusha Keyghobadi   +5 more
doaj   +1 more source

Candidate and non-candidate genes in behavior genetics

Current Opinion in Neurobiology, 2013
In this review we discuss recent developments in psychiatric genetics: on the one hand, studies using whole genome approaches (genome-wide association studies (GWAS) and exome sequencing) are coming close to finding genes and molecular variants that contribute to disease susceptibility; on the other candidate genes, such as the serotonin transporter ...
Flint, Jonathan, Munafò, Marcus R
openaire   +5 more sources

Identification of candidate genes affecting the tibia quality in Nonghua duck

Poultry Science
: The skeleton is a vital organ providing structural support in poultry. Weakness in bone structure can lead to deformities, osteoporosis, cage fatigue, and fractures, resulting in economic losses.
Yinjuan Lu, Bin Wei, Qinglan Yang, Xu Han, Xinxin He, Qiuyu Tao, Shuaixue Jiang, Mengru Xu, Yuan Bai, Tao Zhang, Lili Bai, Jiwei Hu, Hehe Liu, Liang Li   +13 more
doaj   +1 more source

Association between single-nucleotide polymorphisms within candidate genes and fertility in Landrace and Duroc pigs

Acta Veterinaria Scandinavica, 2019
Finding effective predictors of traits related to boar fertility is essential for increasing the efficiency of artificial insemination systems in pig breeding.
Nina Hårdnes Tremoen, Maren Van Son, Ina Andersen-Ranberg, Eli Grindflek, Frøydis Deinboll Myromslien, Ann Helen Gaustad, Dag Inge Våge   +6 more
doaj   +1 more source

Genetics of human neural tube defects [PDF]

, 2009
Neural tube defects (NTDs) are common, severe congenital malformations whose causation involves multiple genes and environmental factors. Although more than 200 genes are known to cause NTDs in mice, there has been rather limited progress in delineating ...
A. J. Copp, Au, Beaudin, Beaudin, Bennett, Birn, Blom, Boyles, Brody, Brown, Carmichael, Carroll, Carroll, Chen, Chen, Chen, Christensen, Christensen, Cockroft, Copp, Copp, Dalal, Davidson, De Marco, De Marco, Deak, Deak, Detrait, Doudney, Dunlevy, Dunlevy, Elmore, Enaw, Epstein, Estibeiro, Etheridge, Franke, Frosst, Gelineau-van Waes, Gonzalez-Herrera, Gos, Greene, Greene, Greene, Greene, Gustavsson, Gustavsson, Harris, Harris, Jensen, Jensen, Jensen, Jessen, Joosten, Kennedy, Khandelwal, Kibar, Kibar, Kibar, Kibar, King, Kirke, Krasnow, Lakkis, Li, Li, Lorenz, Lu, Lu, Lu, McEwen, Mills, Mitchell, Molloy, Montcouquiol, Murdoch, Murdoch, Murdoch, N. D.E. Greene, Narimatsu, Neumann, O'Leary, O'leary, Okano, P. Stanier, Park, Parker, Parle-McDermott, Parle-McDermott, Qian, Relton, Relton, Scott, Shang, Shaw, Shields, Smithells, Stamm, Stamm, Steegers-Theunissen, Stegmann, Strutt, Strutt, Stumpf, Swanson, Swanson, Ting, Toepoel, Trembath, van der Linden, van der Linden, van der Linden, van der Linden, van der Put, van Straaten, Vanaerts, vandenBerg, Vieira, Volcik, Wallingford, Wang, Watanabe, Wilding, Wilson, Wu, Zhang, Zhu, Zhu, Zhu, Zhu, Zhu, Zohn   +131 more
core   +2 more sources

Transcriptomic Characterization of Candidate Genes for Fusarium Resistance in Maize (Zea mays L.)

Pathogens
Fusarium diseases are among the most dangerous fungal diseases of plants. To date, there are no plant protectants that completely prevent fusariosis. Current breeding trends are therefore focused on increasing genetic resistance.
Aleksandra Sobiech, Agnieszka Tomkowiak, Tomasz Jamruszka, Tomasz Kosiada, Julia Spychała, Maciej Lenort, Jan Bocianowski   +6 more
doaj   +1 more source

Creation of a Computational Pipeline to Extract Genes from Quantitative Trait Loci for Diabetes and Obesity [PDF]

, 2015
Type 2 Diabetes is a disease of relative insulin deficiency resulting from a combination of insulin resistance and decreased beta-cell function. Over the past several years, over 60 genes have been identified for Type 2 Diabetes in human genome-wide ...
Fox, Joseph
core   +1 more source

Prediction of gene–phenotype associations in humans, mice, and plants using phenologs [PDF]

, 2013
All authors are with the Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA.
Laurent, Jon M., Marcotte, Edward M., McGary, Kriston L., Singh-Blom, Ulf Martin, Woods, John O.   +4 more
core   +2 more sources

Probing the Gene eXpression Database for candidate genes [PDF]

European Journal of Human Genetics, 1999
We report on a strategy for the identification of candidate genes for multiple malformation syndromes using expression data available in public databases. The basis for this pilot study was the assumption that, for a multiple malformation syndrome, the expression pattern of the causative gene should at least cover the organs or tissues affected by the ...
Steensel, M.A.M. van, Celli, J., Bokhoven, J.H.L.M. van, Brunner, H.G.   +3 more
openaire   +3 more sources