Results 131 to 140 of about 298,386 (364)

Surface‐Coated Inorganic Nanomaterials for Drug Delivery: Chemical Design, Biomedical Applications, and Mechanistic Insights

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review explores how surface‐coated inorganic nanomaterials are chemically engineered for advanced drug delivery. It highlights design principles, coating strategies, and biomedical applications, emphasizing how surface chemistry governs biocompatibility, targeting, and controlled release.
Hossein Daneshgar   +4 more
wiley   +1 more source

Recombinant in vitro assembled hepatitis C virus core particles induce strong specific immunity enhanced by formulation with an oil-based adjuvant

open access: yesBiological Research, 2009
In the present work, immunogenicity of recombinant in vitro assembled hepatitis C virus core particles, HCcAg.120-VLPs, either alone or in combination with different adjuvants was evaluated in BALB/c mice. HCcAg.120-VLPs induced high titers of anti-HCcAg.
NELSON ACOSTA-RIVERO   +15 more
doaj  

A Liquid Crystal Model of Viral DNA Encapsidation

open access: yes, 2017
A liquid crystal continuum modeling framework for icosahedra bacteriophage viruses is developed and tested. The main assumptions of the model are the chromonic columnar hexagonal structure of confined DNA, the high resistance to bending and the phase ...
Arsuaga, Javier   +3 more
core  

A NEW CAPSID [PDF]

open access: yesThe Canadian Entomologist, 1903
Lygus Chagnoni, n. sp.— This species of the genus Lygus is of a form near to L. pabulinus, Linn., in appearance.It is ovate, convex bright green in living specimens, with irregular purplish-brown markings at the base of the membrane, smooth and without bristles, and a silky pubesecence on the sides of the pronotum, which has an orange-yellow border ...
openaire   +1 more source

The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein

open access: yesmBio, 2018
Zika virus (ZIKV) is a significant global health threat, as infection has been linked to serious neurological complications, including microcephaly. Using a human stem cell-derived neural progenitor model system, we find that a critical cellular quality ...
Krystal A. Fontaine   +10 more
semanticscholar   +1 more source

Site-directed mutagenesis of the proposed catalytic amino acids of the Sindbis virus capsid protein autoprotease [PDF]

open access: yes, 1990
The structural proteins of Sindbis virus are translated as a polyprotein precursor that is cleaved upon translation. The capsid protein is postulated to be a serine protease that releases itself from the N terminus of the nascent polyprotein by ...
Hahn, Chang S., Strauss, James H.
core  

PF74 Reinforces the HIV-1 Capsid To Impair Reverse Transcription-Induced Uncoating

open access: yesJournal of Virology, 2018
The capsid-binding small molecule PF74 inhibits HIV-1 infection at early stages and perturbs uncoating. However, the mechanism by which PF74 alters capsid stability and reduces viral infection is presently unknown.
Sanela Rankovic   +3 more
semanticscholar   +1 more source

Antibody Competition Reveals Surface Location of HPV L2 Minor Capsid Protein Residues 17–36

open access: yesViruses, 2017
The currently available nonavalent human papillomavirus (HPV) vaccine exploits the highly antigenic L1 major capsid protein to promote high-titer neutralizing antibodies, but is limited to the HPV types included in the vaccine since the responses are ...
Stephanie M. Bywaters   +5 more
doaj   +1 more source

Thermodynamics of nano-spheres encapsulated in virus capsids

open access: yes, 2009
We investigate the thermodynamics of complexation of functionalized charged nano-spheres with viral proteins. The physics of this problem is governed by electrostatic interaction between the proteins and the nano-sphere cores (screened by salt ions), but
Antonio Šiber   +5 more
core   +1 more source

A Vibrio cholerae viral satellite maximizes its spread and inhibits phage by remodeling hijacked phage coat proteins into small capsids

open access: yeseLife
Phage satellites commonly remodel capsids they hijack from the phages they parasitize, but only a few mechanisms regulating the change in capsid size have been reported.
Caroline M Boyd   +4 more
doaj   +1 more source

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