Results 211 to 220 of about 249,247 (291)
Comparative analysis of deep mutational scanning datasets in enteroviruses A and B identifies functional divergence and therapeutic targets. [PDF]
Álvarez-Rodríguez B +4 more
europepmc +1 more source
ABSTRACT The Australian Crop Mirid (ACM), Sidnia kinbergi Stål (Hemiptera: Miridae), is highly polyphagous and is endemic to Australia. It is widely distributed across Australia and New Zealand and feeds on a wide range of agricultural crops. ACM has traditionally been a pest of forage crops and legumes but has recently emerged as a key pest of several
Kiran Bhusal +3 more
wiley +1 more source
Respiratory enterovirus D68: virology, clinical surveillance, host-pathogen interactions, and therapeutic prospects. [PDF]
Gui Y +7 more
europepmc +1 more source
Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos +16 more
wiley +1 more source
Multiomics Analysis of Arboviral Capsid Targets in Mosquitoes Reveals a Proviral Function of the Chromatin-Remodeling Brahma Complex. [PDF]
Flory C +10 more
europepmc +1 more source
Expression of Glycoprotein B (gB) Correlates With Poor Prognosis in Nasopharyngeal Carcinoma
The extent of EBV lytic replication in NPC has not been fully clarified. Our study demonstrated EBV replication and release in NPC and identified a significant association between expression of the late lytic protein gB and poor prognosis. These findings suggest that late lytic gene products may contribute to tumor progression and that gB represents a ...
Shigetaka Komura +24 more
wiley +1 more source
A novel phage satellite class induces prophage excision in Mycolicibacterium aichiense. [PDF]
Qian HL +5 more
europepmc +1 more source
AAV's widespread application is currently confronting critical challenges. This study established a systematic framework of ‘natural discovery–evolutionary analysis–functional optimization’, providing a new paradigm for the development of next‐generation AAV vectors with clinical‐grade tissue specificity, low immunogenicity, and cross‐species ...
Liyu Zhu +11 more
wiley +1 more source

