Results 201 to 210 of about 249,247 (291)

The double histone fold: Structure, functional implications across the tree of life and relevance to protein design

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract The histone fold is one of the most ancient and versatile structural motifs in protein biology, best known for its role in chromatin organization. A remarkable variation of this motif is the double histone fold (DHF), in which two histone folds are encoded within a single polypeptide chain and assemble intramolecularly into a histone‐like ...
Anna Ranaudo   +3 more
wiley   +1 more source

ICTV Virus Taxonomy Profile: <i>Anelloviridae</i> 2026. [PDF]

open access: yesJ Gen Virol
Kraberger S   +8 more
europepmc   +1 more source

ssRNA bacteriophage metagenomes reveal a diverse set of novel protein families

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract The bacteriophages with single‐stranded RNA (ssRNA) genomes (class Leviviricetes) are among the simplest known viruses that encode only three core proteins: a receptor‐binding protein, a capsid protein, and an RNA‐dependent RNA polymerase. The number of isolated ssRNA phages has remained very low, but the accumulating RNA metagenome data have ...
Jānis Rūmnieks   +3 more
wiley   +1 more source

Family‐level specialization in protein domain insertion architectures

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract Domain insertion creates architectures where one domain interrupts another's sequence. Analysis across 2.7 million classified domains reveals that insertions occur in 20% of multidomain proteins, with 331 families exhibiting consistent architectural roles: 162 function exclusively as hosts, while 169 exclusively serve as inserted modules, such
R. Dustin Schaeffer   +4 more
wiley   +1 more source

Pharmacokinetics, Pharmacodynamics, Efficacy and Drug Resistance Selection of Injectable Long‐Acting Lenacapavir Pre‐Exposure Prophylaxis (PrEP) Against HIV

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Oral pre‐exposure prophylaxis (PrEP) can substantially reduce HIV infection risk when taken as prescribed. However, many individuals struggle adhering to the daily regimen. Twice‐yearly injections of the novel HIV capsid inhibitor lenacapavir (LEN) demonstrated potential in recent PrEP trials.
Hee‐yeong Kim   +3 more
wiley   +1 more source

"Expression of a recombinant chimeric capsid-nucleocapsid protein from bovine leukemia virus genotype 1 for the diagnosis of enzootic bovine leukosis". [PDF]

open access: yesVet Res Commun
Sánchez Gasca JH   +5 more
europepmc   +1 more source

Beyond the Usual Suspects: Emerging Associations Between Epstein‐Barr Virus Infection/Infectious Mononucleosis and Cancers

open access: yesReviews in Medical Virology, Volume 36, Issue 3, May 2026.
ABSTRACT Epstein‐Barr virus (EBV) is a ubiquitous herpesvirus and a causal factor for Burkitt Lymphoma (BL), Hodgkin Lymphoma (HL), gastric carcinoma (GC) and nasopharyngeal carcinoma (NPC). Whether EBV contributes to a wider spectrum of cancers remains uncertain.
Marisa D. Muckian   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy