Results 91 to 100 of about 5,586,089 (360)
Controlling Viral Capsid Assembly with Templating [PDF]
, 2007 We develop coarse-grained models that describe the dynamic encapsidation of functionalized nanoparticles by viral capsid proteins. We find that some forms of cooperative interactions between protein subunits and nanoparticles can dramatically enhance rates and robustness of assembly, as compared to the spontaneous assembly of subunits into empty ...
arxiv +1 more source
Ion-dependent DNA Configuration in Bacteriophage Capsids [PDF]
, 2020 Bacteriophages densely pack their long dsDNA genome inside a protein capsid. The conformation of the viral genome inside the capsid is consistent with a hexagonal liquid crystalline structure. Experiments have confirmed that the details of the hexagonal packing depend on the electrochemistry of the capsid and its environment. In this work, we propose a
arxiv +1 more source
Identification and localization of the structural proteins of anguillid herpesvirus 1
Veterinary Research, 2011 Many of the known fish herpesviruses have important aquaculture species as their natural host, and may cause serious disease and mortality. Anguillid herpesvirus 1 (AngHV-1) causes a hemorrhagic disease in European eel, Anguilla anguilla.
van Beurden Steven J +9 more
doaj +1 more source
Viral chimeras decrypt the role of enterovirus capsid proteins in viral tropism, acid sensitivity and optimal growth temperature. [PDF]
PLoS Pathogens, 2018 Despite their genetic similarities, enteric and respiratory enteroviruses (EVs) have highly heterogeneous biophysical properties and cause a vast diversity of human pathologies.
Léna Royston +10 more
doaj +1 more source
Hepatitis E Virus Lifecycle and Identification of 3 Forms of the ORF2 Capsid Protein.
Gastroenterology, 2018 BACKGROUND & AIMS Hepatitis E virus (HEV) infection is a major cause of acute hepatitis worldwide. Approximately 2 billion people live in areas endemic for HEV and are at risk of infection.
C. Montpellier +19 more
semanticscholar +1 more source
Advanced Science, EarlyView.Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi +20 more
wiley +1 more source
The effect of chemical chaperones on the assembly and stability of HIV-1 capsid protein. [PDF]
PLoS ONE, 2013 Chemical chaperones are small organic molecules which accumulate in a broad range of organisms in various tissues under different stress conditions and assist in the maintenance of a correct proteostasis under denaturating environments.
Ayala Lampel +4 more
doaj +1 more source
Feline Calicivirus Capsid Protein Expression and Capsid Assembly in Cultured Feline Cells [PDF]
Journal of Virology, 1999 ABSTRACT The capsid protein of feline calicivirus (FCV) was expressed by using plasmids containing cytomegalovirus, simian virus 40, or T7 promoters. The strongest expression was achieved with the T7 promoter and coinfection with vaccinia virus expressing the T7 RNA polymerase (MVA/T7pol). The FCV precursor capsid protein was processed to the
Karla Schneider +5 more
openaire +3 more sources
Advanced Science, EarlyView.The salivary sheath protein myosin from SBPH is critical for the formation of the salivary sheath and feeding. However, myosin functions as a HAMP and triggered plant BAK1‐mediated PTI responses, which include the activation of calcium signaling pathways, MAPK phosphorylation, ROS bursts, and cell death, thereby triggering JA pathway.
Liangxuan Qi +12 more
wiley +1 more source
mBioHuman immunodeficiency virus type 1 (HIV-1) capsid, which is the target of the antiviral lenacapavir, protects the viral genome and binds multiple host proteins to influence intracellular trafficking, nuclear import, and integration.
Zachary Ingram +12 more
doaj +1 more source