Evaluation of hepatitis A virus recombinant proteins for detecting anti-HAV IgM and IgG antibodies
Microbiology SpectrumHepatitis A virus (HAV) is a major causative agent of self-limiting liver infections. India was highly endemic for HAV in the past; children were exposed to the virus at an early age without any disease symptoms and developed lifelong immunity.
Supriya Hunderkar +3 more
doaj +1 more source
Development of LC-MS methods for AAV capsid protein quantification and host cell protein profiling
Molecular Therapy: Methods & Clinical DevelopmentAccurate quantification and characterization of recombinant adeno-associated virus (rAAV) capsid proteins are critical for evaluating product quality and safety, ensuring batch consistency, and informing process development of their manufacture.
Theodoros Kontogiannis +6 more
doaj +1 more source
The effect of chemical chaperones on the assembly and stability of HIV-1 capsid protein. [PDF]
PLoS ONE, 2013 Chemical chaperones are small organic molecules which accumulate in a broad range of organisms in various tissues under different stress conditions and assist in the maintenance of a correct proteostasis under denaturating environments.
Ayala Lampel +4 more
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siRNAs targeting HSV-1 capsid proteins.
, 2014 siRNAs targeting HSV-1 capsid proteins.
Kai Zheng (558943) +10 more
core +1 more source
The Triplex-Centric Assembly and Maturation of the Herpesvirus Procapsid
VirusesHerpesviruses are prevalent infectious agents in humans, with complex structures and life cycles. The viability and detail of a model of capsid assembly and maturation can now be examined against the recently available mature herpesvirus capsids ...
J. Bernard Heymann
doaj +1 more source
Viral chimeras decrypt the role of enterovirus capsid proteins in viral tropism, acid sensitivity and optimal growth temperature. [PDF]
PLoS Pathogens, 2018 Despite their genetic similarities, enteric and respiratory enteroviruses (EVs) have highly heterogeneous biophysical properties and cause a vast diversity of human pathologies.
Léna Royston +10 more
doaj +1 more source
Molecular Studies on Bromovirus Capsid Protein
Virology, 1998 Brome mosaic bromovirus (BMV) and cucumber mosaic cucumovirus (CMV) are structurally and genetically very similar. The specificity of the BMV and CMV coat proteins (CPs) during in vivo encapsidation was studied using two RNA3 chimera in which the respective CP genes were exchanged.
Osman, Fatima +3 more
openaire +2 more sources
The capsid protein of human immunodeficiency virus: interactions of HIV‐1 capsid with host protein factors [PDF]
The FEBS Journal, 2009 HIV‐1 is a retrovirus that causes AIDS in humans. The RNA genome of the virus encodes a Gag polyprotein, which is further processed into matrix, capsid and nucleocapsid proteins. These proteins play a significant role at several steps in the viral life cycle.
Anjali P, Mascarenhas +1 more
openaire +2 more sources
Capsid proteins are structurally distant from generic proteins.
, 2013 Each curve plots the empirical cumulative fraction distribution of distances between one set of 56 proteins and their nearest neighbor in the complementary set.
Shanshan Cheng (280254) +1 more
core +1 more source
eLife, 2016 Restriction factors and pattern recognition receptors are important components of intrinsic cellular defenses against viral infection. Mammalian TRIM5α proteins are restriction factors and receptors that target the capsid cores of retroviruses and ...
Jonathan M Wagner +10 more
doaj +1 more source