Results 61 to 70 of about 151,947 (199)
Comparison in structural fold space of capsid proteins and non-capsid ones.
, 2013 Capsid proteins form large, highly symmetric protein shells (left), while generic proteins form other types of complexes (right), exemplified here by an RNA polymerase elongation complex.
Shanshan Cheng (280254) +1 more
core +1 more source
Foamy Virus Budding and Release
Viruses, 2013 Like all other viruses, a successful egress of functional particles from infected cells is a prerequisite for foamy virus (FV) spread within the host. The budding process of FVs involves steps, which are shared by other retroviruses, such as interaction ...
Dirk Lindemann +2 more
doaj +1 more source
Simultaneous membrane and RNA binding by tick-borne encephalitis virus capsid protein.
PLoS Pathogens, 2023 Tick-borne encephalitis virus is an enveloped, pathogenic, RNA virus in the family Flaviviridae, genus Flavivirus. Viral particles are formed when the nucleocapsid, consisting of an RNA genome and multiple copies of the capsid protein, buds through the ...
Lauri Ilmari Aurelius Pulkkinen +8 more
doaj +1 more source
L2, the minor capsid protein of papillomavirus
Virology, 2013 The capsid protein L2 plays major roles in both papillomavirus assembly and the infectious process. While L1 forms the majority of the capsid and can self-assemble into empty virus-like particles (VLPs), L2 is a minor capsid component and lacks the capacity to form VLPs. However, L2 co-assembles with L1 into VLPs, enhancing their assembly.
Wang, Joshua W., Roden, Richard B.S.
openaire +2 more sources
Aquareovirus NS80 Initiates Efficient Viral Replication by Retaining Core Proteins within Replication-Associated Viral Inclusion Bodies. [PDF]
PLoS ONE, 2015 Viral inclusion bodies (VIBs) are specific intracellular compartments for reoviruses replication and assembly. Aquareovirus nonstructural protein NS80 has been identified to be the major constituent for forming globular VIBs in our previous study.
Liming Yan +6 more
doaj +1 more source
The papillomavirus major capsid protein L1
Virology, 2013 The elegant icosahedral surface of the papillomavirus virion is formed by a single protein called L1. Recombinant L1 proteins can spontaneously self-assemble into a highly immunogenic structure that closely mimics the natural surface of native papillomavirus virions. This has served as the basis for two highly successful vaccines against cancer-causing
Buck, Christopher B. +2 more
openaire +2 more sources
Tropism-modification strategies for targeted gene delivery using adenoviral vectors [PDF]
, 2010 Achieving high efficiency, targeted gene delivery with adenoviral vectors is a long-standing goal in the field of clinical gene therapy. To achieve this, platform vectors must combine efficient retargeting strategies with detargeting modifications to ...
Coughlan, L. +20 more
core +1 more source
Synthetic approaches to construct viral capsid-like spherical nanomaterials [PDF]
This feature article describes recent progress in synthetic strategies to construct viral capsid-like spherical nanomaterials using the self-assembly of peptides and/or proteins.
Matsuura, Kazunori +5 more
core +1 more source
An interaction between glutathione and the capsid is required for the morphogenesis of C-cluster enteroviruses. [PDF]
PLoS Pathogens, 2014 Glutathione (GSH) is the most abundant cellular thiol playing an essential role in preserving a reduced cellular environment. Cellular GSH levels can be efficiently reduced by the GSH biosynthesis inhibitor, L-buthionine sulfoximine (BSO). The aim of our
Hsin-Chieh Ma +11 more
doaj +1 more source
mBioHuman immunodeficiency virus type 1 (HIV-1) capsid, which is the target of the antiviral lenacapavir, protects the viral genome and binds multiple host proteins to influence intracellular trafficking, nuclear import, and integration.
Zachary Ingram +12 more
doaj +1 more source