Feline Calicivirus Capsid Protein Expression and Capsid Assembly in Cultured Feline Cells [PDF]
ABSTRACT The capsid protein of feline calicivirus (FCV) was expressed by using plasmids containing cytomegalovirus, simian virus 40, or T7 promoters. The strongest expression was achieved with the T7 promoter and coinfection with vaccinia virus expressing the T7 RNA polymerase (MVA/T7pol). The FCV precursor capsid protein was processed to the
K, Geissler +5 more
openaire +2 more sources
Venezuelan Equine Encephalitis Virus Capsid—The Clever Caper
Venezuelan equine encephalitis virus (VEEV) is a New World alphavirus that is vectored by mosquitos and cycled in rodents. It can cause disease in equines and humans characterized by a febrile illness that may progress into encephalitis.
Lindsay Lundberg +2 more
doaj +1 more source
The SV40 Capsid Is Stabilized by a Conserved Pentapeptide Hinge of the Major Capsid Protein VP1 [PDF]
The simian virus 40 (SV40) outer shell is composed of 72 pentamers of VP1. The core of the VP1 monomer is a beta-barrel with jelly-roll topology and extending N- and C-terminal arms. A pentapeptide hinge, KNPYP, tethers the C-arm to the VP1 beta-barrel core.
Orly, Ben-nun-Shaul +4 more
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Molecular Interactions of Epstein-Barr Virus Capsid Proteins
The capsids of herpesviruses, which comprise major and minor capsid proteins, have a common icosahedral structure with 162 capsomers. An electron microscopic study shows that Epstein-Barr virus (EBV) capsids in the nucleus are immunolabeled by anti-BDLF1
Wen-Hung Wang +4 more
core +1 more source
Characterization of HIV-1 capsid-binding host proteins during infection [PDF]
The human immunodeficiency virus type 1 (HIV-1) capsid is an assembly of over 1,500 capsid (CA) monomers that encapsulates the viral RNA genome. After infection of the cell, this structure dissociates in a process termed uncoating to reveal the reverse ...
Boggs, Emerson Ailidh
core
Protection against myxomatosis and rabbit viral hemorrhagic disease with recombinant myxoma viruses expressing rabbit hemorrhagic disease virus capsid protein [PDF]
Two myxoma virus-rabbit hemorrhagic disease virus (RHDV) recombinant viruses were constructed with the SG33 strain of myxoma virus to protect rabbits against myxomatosis and rabbit viral hemorrhagic disease.
Milon, Alain +13 more
core
Molecular Studies on Bromovirus Capsid Protein
Specific interactions are likely to occur between the highly conserved N-proximal arginine-rich motif (ARM) of Brome mosaic virus (BMV) coat protein (CP) and each of three genomic RNAs and a single subgenomic RNA during in vivo encapsidation. To characterize these interactions, three independent deletions were engineered into a biologically active ...
Osman, Fatima +2 more
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Near-atomic structure of a giant virus
Nucleocytoplasmic large DNA viruses are a group of viruses that infect many eukaryotic hosts. Here, the authors provide a 3.5 Å resolution icosahedrally-averaged capsid structure of Paramecium bursaria chlorella virus 1 and show how 1800 minor capsid ...
Qianglin Fang +11 more
doaj +1 more source
Transportin 3 promotes a nuclear maturation step required for efficient HIV-1 integration.
The HIV/AIDS pandemic is a major global health threat and understanding the detailed molecular mechanisms of HIV replication is critical for the development of novel therapeutics.
Lihong Zhou +5 more
doaj +1 more source
Minor proteins, mobile arms and membrane-capsid interactions in the bacteriophage PRD1 capsid.
Bacteriophage PRD1 shares many structural and functional similarities with adenovirus. A major difference is the PRD1 internal membrane, which acts in concert with vertex proteins to translocate the phage genome into the host.
Huiskonen, JT +6 more
core +1 more source

