Results 11 to 20 of about 6,660,257 (317)
Proceedings of the National Academy of Sciences of the United States of America, 2022 Significance Viruses are the most abundant biological entities on Earth and ubiquitous parasites of cellular life forms. The general scenario for the origin of viruses involves evolution from nonviral replicators, such as plasmids and transposons, via ...
M. Krupovic, K. Makarova, E. Koonin
semanticscholar +1 more source
bioRxiv, 2021 Liquid-liquid phase separation is prone to occur when positively charged proteins interact with nucleic acids. Here, we studied biophysical properties of Dengue (DENV) and Zika (ZIKV) virus capsid proteins to understand the process of RNA genome ...
E. Ambroggio +4 more
semanticscholar +1 more source
Arthritogenic Alphavirus Capsid Protein
Life, 2021 In the past two decades Old World and arthritogenic alphavirus have been responsible for epidemics of polyarthritis, causing high morbidity and becoming a major public health concern. The multifunctional arthritogenic alphavirus capsid protein is crucial for viral infection. Capsid protein has roles in genome encapsulation, budding and virion assembly.
Rao, Shambhavi, Taylor, Adam
openaire +4 more sources
Viruses, 2021 Penetration of the viral genome into a host cell nucleus is critical for initiation of viral replication for most DNA viruses and a few RNA viruses. For herpesviruses, viral DNA ejection into a nucleus occurs when the capsid docks at the nuclear pore ...
José Ramon Villanueva-Valencia +2 more
doaj +1 more source
Viruses, 2023 Herpesviruses are enveloped and have an amorphous protein layer surrounding the capsid, which is termed the tegument. Tegument proteins perform critical functions throughout the viral life cycle.
Soumya Sucharita +2 more
doaj +1 more source
Enhancing Capsid Proteins Capacity in Plant Virus-Vector Interactions and Virus Transmission
Cells, 2021 Vector transmission of plant viruses is basically of two types that depend on the virus helper component proteins or the capsid proteins. A number of plant viruses belonging to disparate groups have developed unusual capsid proteins providing for ...
Alexey Agranovsky
doaj +1 more source
Structures of Three Actinobacteriophage Capsids: Roles of Symmetry and Accessory Proteins
Viruses, 2020 Here, we describe the structure of three actinobacteriophage capsids that infect Mycobacterium smegmatis. The capsid structures were resolved to approximately six angstroms, which allowed confirmation that each bacteriophage uses the HK97-fold to form ...
Jennifer Podgorski +6 more
doaj +1 more source
Role of Genome in the Formation of Conical Retroviral Shells [PDF]
, 2016 Human immunodeficiency virus (HIV) capsid proteins spontaneously assemble around the genome into a protective protein shell called the capsid, which can take on a variety of shapes broadly classified as conical, cylindrical and irregular. The majority of
Erdemci-Tandogan, Gonca +3 more
core +5 more sources
Intracellular nucleic acid delivery by the supercharged dengue virus capsid protein. [PDF]
PLoS ONE, 2013 Supercharged proteins are a recently identified class of proteins that have the ability to efficiently deliver functional macromolecules into mammalian cells.
João Miguel Freire +8 more
doaj +1 more source
Journal of Pharmaceutical and Biomedical Analysis, 2020 To support adeno-associated virus (AAV)-based gene therapy development, characterization of the three capsid viral proteins (VP; VP1/VP2/VP3) from recombinant AAV can offer insights on capsid identity, heterogeneity, and product and process consistency ...
Anita P. Liu +5 more
semanticscholar +1 more source