A snapshot of HIV-1 capsid–host interactions
Current Research in Structural Biology, 2020 From cellular deposition of the HIV-1 capsid to integration of the viral genome, the capsid constitutes a primary target of a variety of host proteins that work to either promote or inhibit HIV-1 infection.
Joshua Temple +3 more
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A capsid-encoded PPxY-motif facilitates adenovirus entry. [PDF]
, 2010 Viruses use cellular machinery to enter and infect cells. In this study we address the cell entry mechanisms of nonenveloped adenoviruses (Ads). We show that protein VI, an internal capsid protein, is rapidly exposed after cell surface attachment and ...
Segura-Morales, Carolina +28 more
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Cellular phosphoinositides and the maturation of bluetongue virus, a non-enveloped capsid virus. [PDF]
, 2013 BACKGROUND: Bluetongue virus (BTV), a member of Orbivirus genus in the Reoviridae family is a double capsid virus enclosing a genome of 10 double-stranded RNA segments. A non-structural protein of BTV, NS3, which is associated with cellular membranes and
Roy, Polly +3 more
core +1 more source
A Unique Role of the Human Cytomegalovirus Small Capsid Protein in Capsid Assembly
mBio, 2022 Human cytomegalovirus (HCMV) is a ubiquitous pathogen causing life-threatening disease in immunocompromised individuals. Virus-specific processes such as capsid assembly and genome packaging can be exploited to design new antiviral strategies.
Eva Maria Borst +8 more
openaire +5 more sources
Three-Dimensional Localization of the Smallest Capsid Protein in the Human Cytomegalovirus Capsid [PDF]
Journal of Virology, 2005 ABSTRACT The smallest capsid proteins (SCPs) of the human herpesviruses differ substantially in size and sequence and are thought to impart some unique aspects of infection to their respective viruses. We used electron cryomicroscopy and antibody labeling to show that the 8-kDa SCP of human cytomegalovirus is attached only to major capsid ...
Xuekui, Yu +6 more
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The Enigmatic Capsid Protein of an Encephalitic Rubivirus [PDF]
Journal of Virology, 2021 The genus Rubivirus was previously comprised of a single member, Rubella virus (RuV), which is spread by airborne or maternal-fetal transmission and only infects humans (1).….
Pratyush Kumar Das, Margaret Kielian
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Iodination of Poliovirus Capsid Proteins
Journal of General Virology, 1977 Summary Iodination of the surface of poliovirus and its artificial empty capsid demonstrated predominant labelling of polypeptide VP 1 on the intact particle and an increased labelling of polypeptide VP 2 on the artificial empty capsid.
T W, Beneke +3 more
openaire +2 more sources
Ab initio modeling of the herpesvirus VP26 core domain assessed by CryoEM density [PDF]
, 2006 Efforts in structural biology have targeted the systematic determination of all protein structures through experimental determination or modeling.
Baker, David +23 more
core +1 more source
Structure, Function, and Interactions of the HIV-1 Capsid Protein
, 2021 The capsid (CA) protein of the human immunodeficiency virus type 1 (HIV-1) is an essential structural component of a virion and facilitates many crucial life cycle steps through interactions with host cell factors.
Megan E. Meuser +3 more
core +1 more source
Near-atomic architecture of Singapore grouper iridovirus and implications for giant virus assembly
Nature Communications, 2023 Singapore grouper iridovirus (SGIV), one of the nucleocytoviricota viruses (NCVs), is a highly pathogenic iridovirid. SGIV infection results in massive economic losses to the aquaculture industry and significantly threatens global biodiversity. In recent
Zhennan Zhao +14 more
doaj +1 more source