The Interaction between the Major Capsid Protein and the Smallest Capsid Protein of Human Cytomegalovirus Is Dependent on Two Linear Sequences in the Smallest Capsid Protein [PDF]
ABSTRACT The assembly of human cytomegalovirus (HCMV) with recombinant systems has not been accomplished. An understanding of specific interactions between individual capsid proteins could point to unique characteristics of the assembly process of HCMV capsids.
Lilin, Lai, William J, Britt
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Assembly of bacteriophage P2 capsids from capsid protein fused to internal scaffolding protein [PDF]
Most tailed bacteriophages with double-stranded DNA genomes code for a scaffolding protein, which is required for capsid assembly, but is removed during capsid maturation and DNA packaging. The gpO scaffolding protein of bacteriophage P2 also doubles as a maturation protease, while the scaffolding activity is confined to a 90 residue C-terminal ...
Jenny R, Chang +2 more
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Ab initio modeling of the herpesvirus VP26 core domain assessed by CryoEM density [PDF]
Efforts in structural biology have targeted the systematic determination of all protein structures through experimental determination or modeling.
Baker, David +23 more
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A Unique Role of the Human Cytomegalovirus Small Capsid Protein in Capsid Assembly
Human cytomegalovirus (HCMV) is a ubiquitous pathogen causing life-threatening disease in immunocompromised individuals. Virus-specific processes such as capsid assembly and genome packaging can be exploited to design new antiviral strategies.
Eva Maria Borst +8 more
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Structure, Function, and Interactions of the HIV-1 Capsid Protein
The capsid (CA) protein of the human immunodeficiency virus type 1 (HIV-1) is an essential structural component of a virion and facilitates many crucial life cycle steps through interactions with host cell factors.
Megan E. Meuser +3 more
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Near-atomic architecture of Singapore grouper iridovirus and implications for giant virus assembly
Singapore grouper iridovirus (SGIV), one of the nucleocytoviricota viruses (NCVs), is a highly pathogenic iridovirid. SGIV infection results in massive economic losses to the aquaculture industry and significantly threatens global biodiversity. In recent
Zhennan Zhao +14 more
doaj +1 more source
A beta-herpesvirus with fluorescent capsids to study transport in living cells. [PDF]
Fluorescent tagging of viral particles by genetic means enables the study of virus dynamics in living cells. However, the study of beta-herpesvirus entry and morphogenesis by this method is currently limited.
Lisa Marcinowski +37 more
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Iodination of Poliovirus Capsid Proteins
Summary Iodination of the surface of poliovirus and its artificial empty capsid demonstrated predominant labelling of polypeptide VP 1 on the intact particle and an increased labelling of polypeptide VP 2 on the artificial empty capsid.
T W, Beneke +3 more
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The Enigmatic Capsid Protein of an Encephalitic Rubivirus [PDF]
The genus Rubivirus was previously comprised of a single member, Rubella virus (RuV), which is spread by airborne or maternal-fetal transmission and only infects humans (1).….
Pratyush Kumar Das, Margaret Kielian
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Bacteriophages and their structural organisation [PDF]
Viruses are extremely small infectious particles that are not visible in a light microscope, and are able to pass through fine porcelain filters. They exist in a huge variety of forms and infect practically all living systems: animals, plants ...
E.V. Orlova, Orlova, Elena
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