Results 21 to 30 of about 144,305 (257)
Iodination of Poliovirus Capsid Proteins
Journal of General Virology, 1977 Summary Iodination of the surface of poliovirus and its artificial empty capsid demonstrated predominant labelling of polypeptide VP 1 on the intact particle and an increased labelling of polypeptide VP 2 on the artificial empty capsid.
T W, Beneke +3 more
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A Unique Role of the Human Cytomegalovirus Small Capsid Protein in Capsid Assembly
mBio, 2022 Human cytomegalovirus (HCMV) is a ubiquitous pathogen causing life-threatening disease in immunocompromised individuals. Virus-specific processes such as capsid assembly and genome packaging can be exploited to design new antiviral strategies.
Eva Maria Borst +8 more
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Viruses, 2014 To get access to the replication site, small non-enveloped DNA viruses have to cross the cell membrane using a limited number of capsid proteins, which also protect the viral genome in the extracellular environment.
Eva Bilkova +2 more
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Neck and capsid architecture of the robust Agrobacterium phage Milano
Communications Biology, 2023 Large gaps exist in our understanding of how bacteriophages, the most abundant biological entities on Earth, assemble and function. The structure of the “neck” region, where the DNA-filled capsid is connected to the host-recognizing tail remains poorly ...
Ravi R. Sonani +9 more
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Three-Dimensional Localization of the Smallest Capsid Protein in the Human Cytomegalovirus Capsid [PDF]
Journal of Virology, 2005 ABSTRACT The smallest capsid proteins (SCPs) of the human herpesviruses differ substantially in size and sequence and are thought to impart some unique aspects of infection to their respective viruses. We used electron cryomicroscopy and antibody labeling to show that the 8-kDa SCP of human cytomegalovirus is attached only to major capsid ...
Xuekui, Yu +6 more
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The Enigmatic Capsid Protein of an Encephalitic Rubivirus [PDF]
Journal of Virology, 2021 The genus Rubivirus was previously comprised of a single member, Rubella virus (RuV), which is spread by airborne or maternal-fetal transmission and only infects humans (1).….
Pratyush Kumar Das, Margaret Kielian
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Nuclear restriction of HIV-1 infection by SUN1
Scientific Reports, 2021 Overexpression of the human Sad-1-Unc-84 homology protein 2 (SUN2) blocks HIV-1 infection in a capsid-dependent manner. In agreement, we showed that overexpression of SUN1 (Sad1 and UNC-84a) also blocks HIV-1 infection in a capsid-dependent manner.
Mirjana Persaud +6 more
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Proton-Linked Dimerization of a Retroviral Capsid Protein Initiates Capsid Assembly [PDF]
Structure, 2009 In mature retroviral particles, the capsid protein (CA) forms a shell encasing the viral replication complex. Human immunodeficiency virus (HIV) CA dimerizes in solution, through its C-terminal domain (CTD), and this interaction is important for capsid assembly.
Bailey, Graham +3 more
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Scientific Reports, 2022 Marseilleviridae is a family of giant viruses, showing a characteristic internal membrane with extrusions underneath the icosahedral vertices. However, such large objects, with a maximum diameter of 250 nm are technically difficult to examine at sub ...
Akane Chihara +6 more
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Capsid-Incorporation of Antigens into Adenovirus Capsid Proteins for a Vaccine Approach [PDF]
Molecular Pharmaceutics, 2010 Some viral vectors are potent inducers of cellular and humoral responses; therefore, viral vectors can be used to vaccinate against cancer or infectious diseases. This report will focus on adenovirus (Ad)-based vectors. Traditional viral-vector vaccination embodies the concept that the vector uses the host-cell machinery to express antigens that are ...
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