Arthritogenic Alphavirus Capsid Protein
In the past two decades Old World and arthritogenic alphavirus have been responsible for epidemics of polyarthritis, causing high morbidity and becoming a major public health concern. The multifunctional arthritogenic alphavirus capsid protein is crucial for viral infection. Capsid protein has roles in genome encapsulation, budding and virion assembly.
Rao, Shambhavi, Taylor, Adam
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Viral capsid proteins are segregated in structural fold space.
Viral capsid proteins assemble into large, symmetrical architectures that are not found in complexes formed by their cellular counterparts. Given the prevalence of the signature jelly-roll topology in viral capsid proteins, we are interested in whether ...
Shanshan Cheng, Charles L Brooks
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Enhancing Capsid Proteins Capacity in Plant Virus-Vector Interactions and Virus Transmission
Vector transmission of plant viruses is basically of two types that depend on the virus helper component proteins or the capsid proteins. A number of plant viruses belonging to disparate groups have developed unusual capsid proteins providing for ...
Alexey Agranovsky
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Intracellular Localization of Blattella germanica Densovirus (BgDV1) Capsid Proteins
Densovirus genome replication and capsid assembly take place in the nucleus of the infected cells. However, the mechanisms underlying such processes as the delivery of virus proteins to the nucleus and the export of progeny virus from the nucleus remain ...
Evgeny N. Kozlov +4 more
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Identification and localization of the structural proteins of anguillid herpesvirus 1 [PDF]
Many of the known fish herpesviruses have important aquaculture species as their natural host, and may cause serious disease and mortality. Anguillid herpesvirus 1 (AngHV-1) causes a hemorrhagic disease in European eel, Anguilla anguilla.
van Beurden Steven J +9 more
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Structures of Three Actinobacteriophage Capsids: Roles of Symmetry and Accessory Proteins
Here, we describe the structure of three actinobacteriophage capsids that infect Mycobacterium smegmatis. The capsid structures were resolved to approximately six angstroms, which allowed confirmation that each bacteriophage uses the HK97-fold to form ...
Jennifer Podgorski +6 more
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Intracellular nucleic acid delivery by the supercharged dengue virus capsid protein. [PDF]
Supercharged proteins are a recently identified class of proteins that have the ability to efficiently deliver functional macromolecules into mammalian cells.
João Miguel Freire +8 more
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Large-scale functional purification of recombinant HIV-1 capsid. [PDF]
During human immunodeficiency virus type-1 (HIV-1) virion maturation, capsid proteins undergo a major rearrangement to form a conical core that protects the viral nucleoprotein complexes.
Magdeleine Hung +7 more
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The Interaction between the Major Capsid Protein and the Smallest Capsid Protein of Human Cytomegalovirus Is Dependent on Two Linear Sequences in the Smallest Capsid Protein [PDF]
ABSTRACT The assembly of human cytomegalovirus (HCMV) with recombinant systems has not been accomplished. An understanding of specific interactions between individual capsid proteins could point to unique characteristics of the assembly process of HCMV capsids.
Lilin, Lai, William J, Britt
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Assembly of bacteriophage P2 capsids from capsid protein fused to internal scaffolding protein [PDF]
Most tailed bacteriophages with double-stranded DNA genomes code for a scaffolding protein, which is required for capsid assembly, but is removed during capsid maturation and DNA packaging. The gpO scaffolding protein of bacteriophage P2 also doubles as a maturation protease, while the scaffolding activity is confined to a 90 residue C-terminal ...
Jenny R, Chang +2 more
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