Flavivirus Capsid Proteins Inhibit the Interferon Response [PDF]
Viruses, 2022 Zika virus (ZIKV) establishes persistent infections in multiple human tissues, a phenomenon that likely plays a role in its ability to cause congenital birth defects and neurological disease. Multiple nonstructural proteins encoded by ZIKV, in particular
Adriana M. Airo +9 more
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Atlas of Interactions Between Decoration Proteins and Major Capsid Proteins of Coliphage N4 [PDF]
VirusesColiphage N4 is a representative species of the Schitoviridae family of bacteriophages. Originally structurally studied in 2008, the capsid structure was solved to 14 Å to reveal an interesting arrangement of Ig-like decoration proteins across the ...
Klem McJarrow-Keller +5 more
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Viral capsid proteins are segregated in structural fold space.
PLoS Computational Biology, 2013 Viral capsid proteins assemble into large, symmetrical architectures that are not found in complexes formed by their cellular counterparts. Given the prevalence of the signature jelly-roll topology in viral capsid proteins, we are interested in whether ...
Shanshan Cheng, Charles L Brooks
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Plant virus movement proteins originated from jelly-roll capsid proteins. [PDF]
PLoS Biology, 2023 Numerous, diverse plant viruses encode movement proteins (MPs) that aid the virus movement through plasmodesmata, the plant intercellular channels. MPs are essential for virus spread and propagation in distal tissues, and several unrelated MPs have been ...
Anamarija Butkovic +3 more
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Divergent Effects of Circoviridae Capsid Proteins on Type I Interferon Signaling [PDF]
PathogensViruses in the Circoviridae family can infect mammals and birds. Porcine circovirus type 2 (PCV2) significantly affects the livestock industry by causing porcine circovirus-associated diseases, such as postweaning multisystem wasting syndrome ...
Anon H. Kosaka +7 more
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Interaction of Poliovirus Capsid Proteins with the Cellular Autophagy Pathway [PDF]
Viruses, 2021 The capsid precursor P1 constitutes the N-terminal part of the enterovirus polyprotein. It is processed into VP0, VP3, and VP1 by the viral proteases, and VP0 is cleaved autocatalytically into VP4 and VP2. We observed that poliovirus VP0 is recognized by
Anna Zimina +4 more
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Characterizing Glycosylation of Adeno-Associated Virus Serotype 9 Capsid Proteins Generated from HEK293 Cells through Glycopeptide Mapping and Released Glycan Analysis [PDF]
MicroorganismsRecombinant adeno-associated viral (AAV) vectors have emerged as prominent gene delivery vehicles for gene therapy. AAV capsid proteins determine tissue specificity and immunogenicity and play important roles in receptor binding, the escape of the virus ...
Yu Zhou, Sonal Priya, Joseph Y. Ong
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RNA packaging and uncoating in simple single-stranded RNA viruses [PDF]
, 2012 Simple (non-enveloped) small, positive-sense single-stranded RNA viruses infect hosts from all kingdoms of life. However, their assembly and uncoating processes remain poorly understood. For turnip crinkle virus (TCV), 3D reconstructions by cryoelectron
Bakker, Saskia
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A capsid-encoded PPxY-motif facilitates adenovirus entry. [PDF]
, 2010 Viruses use cellular machinery to enter and infect cells. In this study we address the cell entry mechanisms of nonenveloped adenoviruses (Ads). We show that protein VI, an internal capsid protein, is rapidly exposed after cell surface attachment and ...
Segura-Morales, Carolina +28 more
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Cellular phosphoinositides and the maturation of bluetongue virus, a non-enveloped capsid virus. [PDF]
, 2013 BACKGROUND: Bluetongue virus (BTV), a member of Orbivirus genus in the Reoviridae family is a double capsid virus enclosing a genome of 10 double-stranded RNA segments. A non-structural protein of BTV, NS3, which is associated with cellular membranes and
Roy, Polly +3 more
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