Results 21 to 30 of about 145,423 (282)
Enhancing Capsid Proteins Capacity in Plant Virus-Vector Interactions and Virus Transmission
Cells, 2021 Vector transmission of plant viruses is basically of two types that depend on the virus helper component proteins or the capsid proteins. A number of plant viruses belonging to disparate groups have developed unusual capsid proteins providing for ...
Alexey Agranovsky
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Structures of Three Actinobacteriophage Capsids: Roles of Symmetry and Accessory Proteins
Viruses, 2020 Here, we describe the structure of three actinobacteriophage capsids that infect Mycobacterium smegmatis. The capsid structures were resolved to approximately six angstroms, which allowed confirmation that each bacteriophage uses the HK97-fold to form ...
Jennifer Podgorski +6 more
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Intracellular nucleic acid delivery by the supercharged dengue virus capsid protein. [PDF]
PLoS ONE, 2013 Supercharged proteins are a recently identified class of proteins that have the ability to efficiently deliver functional macromolecules into mammalian cells.
João Miguel Freire +8 more
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Assembly of bacteriophage P2 capsids from capsid protein fused to internal scaffolding protein [PDF]
Virus Genes, 2010 Most tailed bacteriophages with double-stranded DNA genomes code for a scaffolding protein, which is required for capsid assembly, but is removed during capsid maturation and DNA packaging. The gpO scaffolding protein of bacteriophage P2 also doubles as a maturation protease, while the scaffolding activity is confined to a 90 residue C-terminal ...
Jenny R, Chang +2 more
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Large-scale functional purification of recombinant HIV-1 capsid. [PDF]
PLoS ONE, 2013 During human immunodeficiency virus type-1 (HIV-1) virion maturation, capsid proteins undergo a major rearrangement to form a conical core that protects the viral nucleoprotein complexes.
Magdeleine Hung +7 more
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Proton-Linked Dimerization of a Retroviral Capsid Protein Initiates Capsid Assembly [PDF]
Structure, 2009 In mature retroviral particles, the capsid protein (CA) forms a shell encasing the viral replication complex. Human immunodeficiency virus (HIV) CA dimerizes in solution, through its C-terminal domain (CTD), and this interaction is important for capsid assembly.
Bailey, Graham +3 more
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A snapshot of HIV-1 capsid–host interactions
Current Research in Structural Biology, 2020 From cellular deposition of the HIV-1 capsid to integration of the viral genome, the capsid constitutes a primary target of a variety of host proteins that work to either promote or inhibit HIV-1 infection.
Joshua Temple +3 more
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Viral capsid proteins are segregated in structural fold space.
PLoS Computational Biology, 2013 Viral capsid proteins assemble into large, symmetrical architectures that are not found in complexes formed by their cellular counterparts. Given the prevalence of the signature jelly-roll topology in viral capsid proteins, we are interested in whether ...
Shanshan Cheng, Charles L Brooks
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Diagnostic Potential of Parechovirus Capsid Proteins [PDF]
Journal of Clinical Microbiology, 2003 ABSTRACT To study humoral and cellular immunity against human parechovirus type 1 (HPEV1), the viral capsid proteins VP0, VP1, and VP3 were expressed and purified as glutathione S -transferase (GST)-tagged recombinant proteins. The fusion proteins were used to raise antisera in rabbits.
Annu, Alho +3 more
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Structure of the herpesvirus major capsid protein [PDF]
The EMBO Journal, 2003 Herpes simplex virus-1 (HSV-1) virions are large, complex enveloped particles containing a proteinaceous tegument layer connected to an icosahedral capsid. The major capsid protein, VP5 (149 kDa), makes up both types of capsomere, pentons and hexons. Limited trypsin digestion of VP5 identified a single stable 65 kDa fragment which represents a proposed
Brian R. Bowman
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