Results 21 to 30 of about 6,660,257 (317)
Assembly of bacteriophage P2 capsids from capsid protein fused to internal scaffolding protein [PDF]
Virus Genes, 2010 Most tailed bacteriophages with double-stranded DNA genomes code for a scaffolding protein, which is required for capsid assembly, but is removed during capsid maturation and DNA packaging. The gpO scaffolding protein of bacteriophage P2 also doubles as a maturation protease, while the scaffolding activity is confined to a 90 residue C-terminal ...
Jenny R, Chang +2 more
openaire +2 more sources
Large-scale functional purification of recombinant HIV-1 capsid. [PDF]
PLoS ONE, 2013 During human immunodeficiency virus type-1 (HIV-1) virion maturation, capsid proteins undergo a major rearrangement to form a conical core that protects the viral nucleoprotein complexes.
Magdeleine Hung +7 more
doaj +1 more source
Cluster J Mycobacteriophages: Intron Splicing in Capsid and Tail Genes [PDF]
, 2013 Bacteriophages isolated on Mycobacterium smegmatis mc2155 represent many distinct genomes sharing little or no DNA sequence similarity. The genomes are architecturally mosaic and are replete with genes of unknown function.
Best, AA +17 more
core +11 more sources
Proton-Linked Dimerization of a Retroviral Capsid Protein Initiates Capsid Assembly [PDF]
Structure, 2009 In mature retroviral particles, the capsid protein (CA) forms a shell encasing the viral replication complex. Human immunodeficiency virus (HIV) CA dimerizes in solution, through its C-terminal domain (CTD), and this interaction is important for capsid assembly.
Bailey, Graham +3 more
openaire +3 more sources
A snapshot of HIV-1 capsid–host interactions
Current Research in Structural Biology, 2020 From cellular deposition of the HIV-1 capsid to integration of the viral genome, the capsid constitutes a primary target of a variety of host proteins that work to either promote or inhibit HIV-1 infection.
Joshua Temple +3 more
doaj +1 more source
Diagnostic Potential of Parechovirus Capsid Proteins [PDF]
Journal of Clinical Microbiology, 2003 ABSTRACT To study humoral and cellular immunity against human parechovirus type 1 (HPEV1), the viral capsid proteins VP0, VP1, and VP3 were expressed and purified as glutathione S -transferase (GST)-tagged recombinant proteins. The fusion proteins were used to raise antisera in rabbits.
Annu, Alho +3 more
openaire +2 more sources
The FEBS Journal, 2019 Post‐translational modifications in viral capsids are known to fine‐tune and regulate several aspects of the infective life cycle of several viruses in the host.
B. Mary +4 more
semanticscholar +1 more source
Near-atomic architecture of Singapore grouper iridovirus and implications for giant virus assembly
Nature Communications, 2023 Singapore grouper iridovirus (SGIV), one of the nucleocytoviricota viruses (NCVs), is a highly pathogenic iridovirid. SGIV infection results in massive economic losses to the aquaculture industry and significantly threatens global biodiversity. In recent
Zhennan Zhao +14 more
doaj +1 more source
Rotavirus Capsid Protein VP5* Permeabilizes Membranes [PDF]
Journal of Virology, 1999 ABSTRACT Proteolytic cleavage of the VP4 outer capsid spike protein into VP8* and VP5* proteins is required for rotavirus infectivity and for rotavirus-induced membrane permeability. In this study we addressed the function of the VP5* cleavage fragment in permeabilizing membranes.
E, Denisova +6 more
openaire +2 more sources
Viruses, 2014 To get access to the replication site, small non-enveloped DNA viruses have to cross the cell membrane using a limited number of capsid proteins, which also protect the viral genome in the extracellular environment.
Eva Bilkova +2 more
doaj +1 more source