Results 71 to 80 of about 5,586,089 (360)
Radial distribution of RNA genome packaged inside spherical viruses [PDF]
, 2008 The problem of RNA genomes packaged inside spherical viruses is studied. The viral capsid is modeled as a hollowed sphere. The attraction between RNA molecules and the inner viral capsid is assumed to be non-specific and occurs at the inner capsid surface only.
arxiv +1 more source
A theory for viral capsid assembly around electrostatic cores [PDF]
Hagan, M.F., A theory for viral capsid assembly around
electrostatic cores, J. Chem. Phys., 2009, v130, 114902, 2008 We develop equilibrium and kinetic theories that describe the assembly of viral capsid proteins on a charged central core, as seen in recent experiments in which brome mosaic virus (BMV) capsids assemble around nanoparticles functionalized with polyelectrolyte.
arxiv +1 more source
Micro‐ and Nano‐Bots for Infection Control
Advanced Materials, EarlyView.This review presents a strategic vision for integrating micro‐ and nanobots in the pipeline for infection diagnosis, prevention, and treatment. To develop these robots as a practical solution for infection management, their design principles are clarified based on their propulsion mechanisms and then categorized infection management domains based on ...
Azin Rashidy Ahmady +5 more
wiley +1 more source
Foamy Virus Budding and Release
Viruses, 2013 Like all other viruses, a successful egress of functional particles from infected cells is a prerequisite for foamy virus (FV) spread within the host. The budding process of FVs involves steps, which are shared by other retroviruses, such as interaction ...
Dirk Lindemann +2 more
doaj +1 more source
An interaction between glutathione and the capsid is required for the morphogenesis of C-cluster enteroviruses. [PDF]
PLoS Pathogens, 2014 Glutathione (GSH) is the most abundant cellular thiol playing an essential role in preserving a reduced cellular environment. Cellular GSH levels can be efficiently reduced by the GSH biosynthesis inhibitor, L-buthionine sulfoximine (BSO). The aim of our
Hsin-Chieh Ma +11 more
doaj +1 more source
Understanding Flavivirus Capsid Protein Functions: The Tip of the Iceberg
Pathogens, 2020 Flaviviruses are enveloped positive-sense single-stranded RNA arboviruses, infectious to humans and many other animals and are transmitted primarily via tick or mosquito vectors.
Stephanea L. Sotcheff, Andrew L. Routh
semanticscholar +1 more source
Mimicking Biochemical Traits with a Synthetic Lipid Nanoparticles SARS‐COV‐2 Model
Advanced Therapeutics, EarlyView.A synthetic virus model developed using lipid nanoparticles, which incorporate encapsulated mRNA and nucleocapsid (N) protein along with surface‐conjugated spike (S) protein, mimics the characteristics of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), allowing for the advancement of diagnostic product assessment.
Ignasia Handipta Mahardika +7 more
wiley +1 more source
Aquareovirus NS80 Initiates Efficient Viral Replication by Retaining Core Proteins within Replication-Associated Viral Inclusion Bodies. [PDF]
PLoS ONE, 2015 Viral inclusion bodies (VIBs) are specific intracellular compartments for reoviruses replication and assembly. Aquareovirus nonstructural protein NS80 has been identified to be the major constituent for forming globular VIBs in our previous study.
Liming Yan +6 more
doaj +1 more source
Emerging Therapeutic Strategies for Hearing Loss
Advanced Therapeutics, EarlyView.Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han +9 more
wiley +1 more source
Mechanisms of viral capsid assembly around a polymer [PDF]
, 2010 Capsids of many viruses assemble around nucleic acids or other polymers. Understanding how the properties of the packaged polymer affect the assembly process could promote biomedical efforts to prevent viral assembly or nanomaterials applications that exploit assembly.
arxiv +1 more source