Results 1 to 10 of about 99,888 (166)

Frequency and Antibiotics Resistance of Extended-Spectrum Beta-Lactamase (ESBLs) Producing Escherichia coli and Klebsiella pneumoniae Isolated from Patients in Gaza Strip, Palestine

Journal of Medical Microbiology and Infectious Diseases, 2021
Introduction: Extended-Spectrum β-Lactamases (ESBLs) hydrolyze broadspectrum cephalosporin, monobactam, and penicillin. This study investigated ESBL-producing Escherichia coli and Klebsiella pneumoniae bacteria in the Gaza strip and explored their ...
Ghassan Tayh, Nahed Al Laham, Imene Fhoula, Nahed Abedelateef, Mohamed El-Laham, Abed Elkader Elottol, Karim Ben Slama   +6 more
doaj   +1 more source

Characteristics of Klebsiella bloodstream infections and risk factors for carbapenem-resistant Klebsiella infections in children

Trends in Pediatrics, 2023
Objective: Klebsiella spp. is a common and severe pathogen of bloodstream infections (BSI) due to gram-negative bacilli. Carbapenems are commonly used agents for the treatment of serious infections.
Aysun Yahşi, Gülsüm Iclal Bayhan, Emel Arslan, Muhammed Yasin Gökdöl, Beyza Nur Atay, Seren Karaciğer, Saliha Kanık Yüksek, Belgin Gülhan, Aslınur Özkaya Parlakay   +8 more
doaj   +1 more source

Phenotypic detection of metallo-beta-lactamase production in clinical isolates of Escherichia coli and Klebsiella pneumoniae in a tertiary care hospital

MGM Journal of Medical Sciences, 2022
Introduction: Carbapenem resistance due to metallo-beta-lactamase (MBL)-producing bacteria is an emerging threat worldwide. This study aimed to detect the MBL production in clinical isolates of E.
Smita S Kulkarni, Manjushree V Mulay
doaj   +1 more source

First Belgian Report of Ertapenem Resistance in an ST11 Klebsiella Pneumoniae Strain Isolated from a Dog Carrying bla_SCO-1 and bla_DHA-1 Combined with Permeability Defects

Antibiotics, 2022
Klebsiella pneumoniae of sequence type (ST) 11 is a hyper-epidemic nosocomial clone, which is spreading worldwide among humans and emerging in pets. This is the first report, to the best of our knowledge, of multidrug-resistant (MDR) K.
Hanne Debergh, Margo Maex, Cristina Garcia-Graells, Cécile Boland, Marc Saulmont, Koenraad Van Hoorde, Claude Saegerman   +6 more
doaj   +1 more source

Aeromonas dhakensis: Clinical Isolates with High Carbapenem Resistance

Pathogens, 2022
Aeromonas dhakensis is ubiquitous in aquatic habitats and can cause life-threatening septicaemia in humans. However, limited data are available on their antimicrobial susceptibility testing (AST) profiles.
Suat Moi Puah, Wei Ching Khor, Kyaw Thu Aung, Tien Tien Vicky Lau, S. D. Puthucheary, Kek Heng Chua   +5 more
doaj   +1 more source

A review on bacterial resistance to carbapenems: epidemiology, detection and treatment options

Future Science OA, 2020
Carbapenems are a class of antimicrobial agents reserved for infections caused by multidrug-resistant microorganisms. The emergence of carbapenem resistance has become a serious public health threat.
Ann A Elshamy, Khaled M Aboshanab
doaj   +1 more source

Clinical impact of carbapenems in critically ill patients with valproic acid therapy: A propensity-matched analysis

Frontiers in Neurology, 2023
BackgroundValproic acid (VPA) is one of the most widely used broad-spectrum antiepileptic drugs, and carbapenems (CBPs) remain the drug of choice for severe infection caused by multidrug-resistant bacteria in critically ill patients.
Shu-Chen Hsiao, Wei-Hung Lai, I-Ling Chen, I-Ling Chen, Fu-Yuan Shih   +4 more
doaj   +1 more source

OXA-48 Carbapenemase-Producing Enterobacterales in Spanish Hospitals: An Updated Comprehensive Review on a Rising Antimicrobial Resistance

Antibiotics, 2021
Carbapenemase-producing Enterobacterales (CPE) are significant contributors to the global public health threat of antimicrobial resistance. OXA-48-like enzymes and their variants are unique carbapenemases with low or null hydrolytic activity toward ...
Mario Rivera-Izquierdo, Antonio Jesús Láinez-Ramos-Bossini, Carlos Rivera-Izquierdo, Jairo López-Gómez, Nicolás Francisco Fernández-Martínez, Pablo Redruello-Guerrero, Luis Miguel Martín-delosReyes, Virginia Martínez-Ruiz, Elena Moreno-Roldán, Eladio Jiménez-Mejías   +9 more
doaj   +1 more source

Prevalence of bla_KPC-2, bla_KPC-3 and bla_KPC-30—Carrying Plasmids in Klebsiella pneumoniae Isolated in a Brazilian Hospital

Pathogens, 2021
Klebsiella pneumoniae carbapenemase (KPC) actively hydrolyzes carbapenems, antibiotics often used a last-line treatment for multidrug-resistant bacteria. KPC clinical relevance resides in its widespread dissemination.
Letícia B. Migliorini, Romário O. de Sales, Paula C. M. Koga, Andre M. Doi, Anja Poehlein, Alexandra R. Toniolo, Fernando G. Menezes, Marines D. V. Martino, Ana C. Gales, Holger Brüggemann, Patricia Severino   +10 more
doaj   +1 more source

Polymorphic Crystallization Design to Prevent the Degradation of the β-Lactam Structure of a Carbapenem

Crystals, 2021
The cooling crystallization of carbapenem CS-023 was performed at 25 °C in an aqueous solution. Tetrahydrate crystals (form H) were obtained. Hydrate crystals are promising drugs, but there has been problems in manufacturing such crystals. During cooling
Shinji Matsuura, Koichi Igarashi, Masayuki Azuma, Hiroshi Ooshima   +3 more
doaj   +1 more source