Results 1 to 10 of about 114,909 (286)

Identification and infection control of carbapenem-resistant Enterobacterales in intensive care units [PDF]

Acute and Critical Care, 2021
Infections with multidrug-resistant organisms among patients in intensive care units (ICUs) are associated with high mortality. Among multidrug-resistant organisms, carbapenem-resistant Enterobacterales (CRE) harbor important pathogens for healthcare ...
Jongyoun Yi, Kye-Hyung Kim
doaj   +1 more source

SURVEILLANCE OF CARBAPENEM-RESISTANT GRAM-NEGATIVE BACTERIA FROM ANIMAL SOURCES IN MATHURA REGION, UTTAR PRADESH, INDIA [PDF]

Exploratory Animal and Medical Research, 2022
A cross-sectional study was conducted to determine the prevalence of Carbapenem-resistant Gram-negative bacteria (CR-GNB) in animals. The study involves one hundred eighty-four GNB isolates from 214 samples (feces, milk, pus, and uterine discharge ...
A. Arun, U. Jaiswal , S. Tripathi , A. P. Singh , S. Choudhury, S. N. Prabhu   +5 more
doaj   +1 more source

Prevalence of bla_KPC-2, bla_KPC-3 and bla_KPC-30—Carrying Plasmids in Klebsiella pneumoniae Isolated in a Brazilian Hospital

Pathogens, 2021
Klebsiella pneumoniae carbapenemase (KPC) actively hydrolyzes carbapenems, antibiotics often used a last-line treatment for multidrug-resistant bacteria. KPC clinical relevance resides in its widespread dissemination.
Letícia B. Migliorini, Romário O. de Sales, Paula C. M. Koga, Andre M. Doi, Anja Poehlein, Alexandra R. Toniolo, Fernando G. Menezes, Marines D. V. Martino, Ana C. Gales, Holger Brüggemann, Patricia Severino   +10 more
doaj   +1 more source

Polymorphic Crystallization Design to Prevent the Degradation of the β-Lactam Structure of a Carbapenem

Crystals, 2021
The cooling crystallization of carbapenem CS-023 was performed at 25 °C in an aqueous solution. Tetrahydrate crystals (form H) were obtained. Hydrate crystals are promising drugs, but there has been problems in manufacturing such crystals. During cooling
Shinji Matsuura, Koichi Igarashi, Masayuki Azuma, Hiroshi Ooshima   +3 more
doaj   +1 more source

In silico Evolution and Comparative Genomic Analysis of IncX3 Plasmids Isolated From China Over Ten Years

Frontiers in Microbiology, 2021
IncX3 plasmids are correlated with the dissemination and acquisition of carbapenem resistance in Enterobacteriaceae and have been prevalent in China over the last 10 years.
Baomo Liu, Baomo Liu, Yingyi Guo, Ningjing Liu, Jiong Wang, Feifeng Li, Likang Yao, Chao Zhuo   +7 more
doaj   +1 more source

Molecular Characteristics and Quantitative Proteomic Analysis of Klebsiella pneumoniae Strains with Carbapenem and Colistin Resistance

Antibiotics, 2022
Carbapenem-resistant Klebsiella pneumoniae (CRKP) are usually multidrug resistant (MDR) and cause serious therapeutic problems. Colistin is a critical last-resort therapeutic option for MDR bacterial infections.
Ling Hao, Xiao Yang, Huiling Chen, Zexun Mo, Yujun Li, Shuquan Wei, Ziwen Zhao   +6 more
doaj   +1 more source

A Systematic Review of the Effect of Therapeutic Drug Monitoring on Patient Health Outcomes during Treatment with Carbapenems

Antibiotics, 2022
Adjusting dosing regimens based on measurements of carbapenem levels may improve carbapenem exposure in patients. This systematic review aims to describe the effect carbapenem therapeutic drug monitoring (TDM) has on health outcomes, including the ...
Timothy N. Luxton, Natalie King, Christoph Wälti, Lars J. C. Jeuken, Jonathan A. T. Sandoe   +4 more
doaj   +1 more source

First Belgian Report of Ertapenem Resistance in an ST11 Klebsiella Pneumoniae Strain Isolated from a Dog Carrying bla_SCO-1 and bla_DHA-1 Combined with Permeability Defects

Antibiotics, 2022
Klebsiella pneumoniae of sequence type (ST) 11 is a hyper-epidemic nosocomial clone, which is spreading worldwide among humans and emerging in pets. This is the first report, to the best of our knowledge, of multidrug-resistant (MDR) K.
Hanne Debergh, Margo Maex, Cristina Garcia-Graells, Cécile Boland, Marc Saulmont, Koenraad Van Hoorde, Claude Saegerman   +6 more
doaj   +1 more source

Differential DNA accessibility to polymerase enables 30-minute phenotypic β-lactam antibiotic susceptibility testing of carbapenem-resistant Enterobacteriaceae [PDF]

, 2020
The rise in carbapenem-resistant Enterobacteriaceae (CRE) infections has created a global health emergency, underlining the critical need to develop faster diagnostics to treat swiftly and correctly.
Garner, Omai B., Ismagilov, Rustem F., Liaw, Eric J., Savela, Emily S., Schoepp, Nathan G., Winnett, Alexander   +5 more
core   +1 more source

Severe bloodstream infection due to KPC-producer e coli in a renal transplant recipient treated with the double-carbapenem regimen and analysis of in vitro synergy testing a case report [PDF]

, 2016
Transplant recipients are at high risk of infections caused by multidrug resistant microorganisms. Due to the limited thera- peutic options, innovative antimicrobial combinations against carbape- nem-resistant Enterobacteriaceae causing severe infections
CIPOLLA, ALESSIA, D'ABRAMO, ALESSANDRA, DE ANGELIS, Massimiliano, Favaro, Marco, Ferretti, Giancarlo, GIZZI, FRANCESCA, IANNETTA, MARCO, MASCELLINO, Maria Teresa, MASTROIANNI, Claudio Maria, OLIVA, ALESSANDRA, RUSSO, Gianluca, VULLO, Vincenzo   +11 more
core   +1 more source