Results 71 to 80 of about 810,489 (200)

High proportion of carbapenemase-producing Escherichia coli and Klebsiella pneumoniae among extended-spectrum β-lactamase-producers in Nigerian hospitals

Journal of Global Antimicrobial Resistance, 2020
Objectives: Carbapenem-resistant Enterobacterales are a global problem, however little is known about the burden and origin of carbapenem resistance in Africa. The objectives of this study were to determine the proportion of carbapenem-resistant isolates
Adesola Olalekan, Francis Onwugamba, Bamidele Iwalokun, Alexander Mellmann, Karsten Becker, Frieder Schaumburg   +5 more
doaj   +1 more source

AI‐Assisted SERS in Bacterial Diagnosis and Antimicrobial Susceptibility Testing: Advances, Gaps, and Translational Pathways

Advanced Sensor Research, Volume 5, Issue 9, September 2026.
This review examines recent advances in integrating artificial intelligence (AI) with surface‐enhanced Raman spectroscopy (SERS) for the detection of pathogenic bacteria and evaluation of drug resistance phenotypes. Key challenges in clinical translation are critically discussed, along with prospective solutions and future research directions ...
Chen Liu, Yu Liu, Junlu Wang, Yujie Liu, Qijia Zhan, Jiangang Liu, Ruoping Chen, Kun Zhang   +7 more
wiley   +1 more source

Carbapenem-resistant Enterobacterales across the UK: a nationwide study of carbapenemase testing and novel antimicrobial activity

BACKGROUND: Carbapenem-resistant Enterobacterales (CRE) are increasing in the UK, but the drivers of this rise and effective treatment options remain uncertain.
Jacquelyn McCormick (6861608), Katie Hopkins (24504518), Gareth Hughes (18689), Stuart Drazich-Taylor (24504503), Kate Beard (10954315), Mohammed Elnour (24504515), Tahira Mohammed (24504497), National Infection Team Collaborative for Audit and Research CRE-DITS Study Group (24504524), Gavin Connolly (23154982), Nicole Stoesser (220513), Louis Grandjean (118150), Preetha Shibu (24504488), Alicia Demirjian (6576746), Jonathan WS Cattrall (24504452), Swati Jain (569859), Jane Democratis (7588499), Andrew Kirby (47075), Krishna Banavathi (24504467), Rebecca Lester (4396492), Nathan Moore (363059), Joseph V Thompson (24504485), Ana Lima Soares (24504521), Katie Drury (19670767), James Hatcher (17367799), Rasika Pahalage (24504464), Felicity Ryan (24504482), Durdana Parveen Jamal Khan (24504458), Ruth Elizabeth Shorrocks (24504473), Thomas Harrison (292487), David W Wareham (24504461), Jasmin Islam (13953552), Ioannis Baltas (12454218), Neetu Adhikaree (24504479), David Ball (142024), Samuel Lipworth (24504509), Christopher James Donaldson (24504455), Abid Hussain (375044), David Jenkins (295958), Samuel Fowler (20017296), Gary Bonnici (24504494), Marie Anne Chattaway (12732773), Alvaro Sanchez Martinez (24504506), Kerryanne Brown (24504500), Ekta Ale (24504491), Borana Drazho (24504470), Mariyam Mirfenderesky (13848887), Bethan England (24504449), James Moore (22922), Amy Carroll (13487209), Wah Wah Hlaing (24504476), David Crawford-Jones (24504512)   +50 more
core   +3 more sources

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, Volume 2, Issue 3, September 2026.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Global Escalation in Carbapenem-Resistant Enterobacterales and Carbapenem-Resistant Acinetobacter baumannii Infections

Biomedical and Biotechnology Research Journal (BBRJ), 2023
Rise in carbapenem-resistant Gram-negative bacterial infections, especially among immunocompromised patients in healthcare settings is an imminent threat as they are difficult to treat and result in a prolonged length of hospital stay, frequent treatment failures, increased economic burden on the patient and the nation, and a ...
openaire   +2 more sources

A Selective Medium for Screening Ceftazidime/Avibactam Resistance in Carbapenem-Resistant Enterobacterales

Frontiers in Microbiology, 2022
Ceftazidime/avibactam (CZA) is an alternative antibiotic used for the treatment of infections caused by carbapenem-resistant Enterobacterales (CRE). However, the CZA-resistant CRE strains have been detected worldwide. Therefore, it is critical to screen CZA-resistant CRE strains in colonized patients or a specific population so as to rapidly implement ...
Weiliang Zeng, Wenli Liao, Wenli Liao, Yajie Zhao, Lingbo Wang, Hongyun Shu, Huaiyu Jia, Tao Chen, Ying Zhang, Tieli Zhou, Qing Wu   +10 more
openaire   +3 more sources

Association between antimicrobial use and the detection rates of carbapenem-resistant Enterobacterales: long-term surveillance results from a single centre

Infection Prevention in Practice
Summary: Background: Carbapenems are vital for treating Enterobacterales infections. However, the emergence of carbapenem-resistant Enterobacterales (CRE), mediated by carbapen-emases or otherwise, has become a global concern due to increased morbidity ...
Shinobu Hirayama, Mariko Otani, Hinako Murakami, Maki Sakamoto, Kazuhiro Tateda, Takahiro Matsumoto, Takashi Sugita   +6 more
doaj   +1 more source

Dose Selection for Ceftibuten Combined with Avibactam Tomilopil, a Potential Oral Alternative to Carbapenems for Patients with Complicated Urinary Tract Infections

The Journal of Clinical Pharmacology, Volume 66, Issue 9, September 2026.
Abstract There are currently no oral treatment options for infections caused by extended spectrum β‑lactamase‐producing Enterobacterales. Avibactam tomilopil, a novel oral prodrug of avibactam, is being developed in combination with the oral cephalosporin, ceftibuten, as a potential treatment for patients with complicated urinary tract infections ...
Siddhee A. Sahasrabudhe, Satoshi Shoji, Abhijeet S. Jakate, Bisrat K. Abraham, Sima S. Toussi, Benjamin J. Maligalig, Amanda S. Darekar, Sakambari Tripathy, Constantino Kantaridis, Josue K. Mfopou, Oxana Selivanova, Arthur Bergman, Negar Niki Alami, Ravi Shankar P. Singh   +13 more
wiley   +1 more source

Combating resistant pathogens: exploring the efficacy of eravacycline utilization in multidrug-resistant infections

Microbiology Spectrum
Eravacycline, FDA-approved for complicated intra-abdominal infections, is increasingly used off-label for multidrug-resistant infections, including carbapenem-resistant Enterobacterales, Stenotrophomonas maltophilia, and carbapenem-resistant ...
Kiara Patino, Ryan Vathy, Ben Albrecht, Sujit Suchindran, Sarah B. Green   +4 more
doaj   +1 more source

Microbial Signals in Cancer: Dissecting Host–Microbiota–Tumor Interactions and Potential Therapeutic Strategy

MedComm, Volume 7, Issue 9, September 2026.
Microbial signals from gut and tumor‐resident bacteria, fungi, viruses, and bacteriophages reshape immune and metabolic networks within the tumor microenvironment, thereby influencing cancer progression, treatment response. Therapeutic modulations, including dietary interventions, probiotics, antibiotics, fecal microbiota transplantation, engineered ...
Juan Lu, Mengjuan Xuan, Liang Yu, Zhongyang Xie, Qingfei Chu, Shihui Wei, Tuokai Wang, Chen Xue, Lanjuan Li   +8 more
wiley   +1 more source