Results 71 to 80 of about 11,802 (200)

Role of Gram‐Negative Bacterial Infections in Acute‐On‐Chronic Liver Failure

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Acute‐on‐chronic liver failure (ACLF) is a systemic disease characterised by an acute clinical deterioration of pre‐existing liver cirrhosis leading to multiple organ failure due to systemic inflammation. It may be triggered by the translocation of bacteria and bacterial compounds across the gut barrier.
Camilla Cadoli, Volker Müller, Christoph Welsch, Heiko Mühl, Jonel Trebicka, Volkhard A. J. Kempf   +5 more
wiley   +1 more source

Clinical Experience with Ceftazidime-Avibactam for the Treatment of Infections due to Multidrug-Resistant Gram-Negative Bacteria Other than Carbapenem-Resistant Enterobacterales [PDF]

, 2020
Experience in real clinical practice with ceftazidime-avibactam for the treatment of serious infections due to gram-negative bacteria (GNB) other than carbapenem-resistant Enterobacterales (CRE) is very ...
Del Puente F., Luzzati, Roberto, Carbonara, Sergio, Sergio Carbonara, Nadia Castaldo, Sepulcri, Chiara, Bassetti, Matteo, Capone, Alessandro, Raumer F., Antonio Vena, Meschiari M., Corcione, S., De Rosa, F. G., Francesco De Rosa, Castaldo, Nadia, Francesca Raumer, Alessandra Oliva, Capone A., Roberto Luzzati, Claudio Mastroianni, Cascio A., Mastroianni, Claudio Maria, Puente, Filippo Del, Mastroianni C. M., Filippo Puente, De Rosa F. G., Silvia Boni, Cattelan A., Antonio Cascio, Cattelan, Annamaria, Meschiari, Marianna, Mussini, Cristina, Marianna Meschiari, Daniele Giacobbe, Silvia Corcione, Vena A., Vena, Antonio, Corcione, Silvia, Carbonara S., Raumer, Francesca, Corcione S., Oliva, Alessandra, Bassetti M., for the Ceftabuse Study Group, Boni, Silvia, Annamaria Cattelan, Alessandro Capone, Rosa, Francesco Giuseppe De, Giacobbe, Daniele Roberto, Chiara Sepulcri, Oliva A., Sepulcri C., Cristina Mussini, Ceftabuse Study Group, Giacobbe D. R., Cascio, Antonio, Boni S., Mussini C., Matteo Bassetti, Castaldo N., Luzzati R.   +60 more
core   +1 more source

Evaluation of the inoculum effect of new antibiotics against carbapenem-resistant enterobacterales

Clinical Microbiology and Infection, 2022
New antibiotics have been developed to treat multidrug-resistant Enterobacterales. We evaluated the impact of the inoculum size on minimal inhibitory concentrations (MICs) of recently commercialized antibiotics.We focused on 40 clinical carbapenemase-producing Enterobacterales and evaluated the impact of the inoculum size on the MICs to cefiderocol and
Maxime, Danjean, Claire Amaris, Hobson, Maud, Gits-Muselli, Céline, Courroux, Audrey, Monjault, Stéphane, Bonacorsi, André, Birgy   +6 more
openaire   +2 more sources

Meropenem–Vaborbactam for the Treatment of Post-Neurosurgical Meningitis Caused by KPC Producer Klebsiella Pneumoniae: A Case Report and Review of the Literature

Antibiotics
Meningitis and ventriculitis, due to carbapenem-resistant Enterobacterales, are frequently associated with significant morbidity and mortality. In the case of multi-drug-resistant pathogens, it is necessary to consider the limited susceptibility profile ...
Leonardo Francesco Rezzonico, Francesco Peracchi, Marta Vecchi, Gabriele Bassi, Marco Merli, Nicholas Brian Bana, Giovanna Travi, Fulvio Crippa, Massimo Puoti   +8 more
doaj   +1 more source

Antibiotics in Veterinary Ophthalmology: Resistance, Stewardship, and Emerging Antibiotic‐Sparing Strategies

Veterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Antimicrobial resistance (AMR) is a growing challenge in veterinary ophthalmology, particularly in cases of bacterial keratitis, where progressive stromal infection can threaten vision and globe integrity within hours to days. This review synthesizes current evidence on pathogen distribution, antimicrobial susceptibility profiles, multidrug ...
Lionel Sebbag, Oren Pe'er
wiley   +1 more source

Carbapenem resistance determinants and their transmissibility among clinically isolated Enterobacterales in Lebanon

Journal of Infection and Public Health, 2023
The occurrence of carbapenem-resistant bacterial infections has increased significantly over the years with Gram-negative bacteria exhibiting the broadest resistance range. In this study we aimed to investigate the genomic characteristics of clinical carbapenem-resistant Enterobacterales (CRE).Seventeen representative multi-drug resistant (MDR ...
Jennifer Moussa, Elie Nassour, Elio Tahan, Mira El Chaar, Tamima Jisr, Sima Tokajian   +5 more
openaire   +3 more sources

Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu, Bayinqiaoge, Xi Lu, Xin Wang, Rongfeng Wang, Yi Li, Shi‐Yang Tang, Chengchen Zhang   +7 more
wiley   +1 more source

Guidelines for Antibacterial Treatment of Carbapenem-Resistant Enterobacterales Infections

Infection & Chemotherapy
This guideline aims to promote the prudent use of antibacterial agents for managing carbapenem-resistant Enterobacterales (CRE) infections in clinical practice in Korea. The general section encompasses recommendations for the management of common CRE infections and diagnostics, whereas each specific section is structured with key questions that are ...
Se Yoon Park, Yae Jee Baek, Jung Ho Kim, Hye Seong, Bongyoung Kim, Yong Chan Kim, Jin Gu Yoon, Namwoo Heo, Song Mi Moon, Young Ah Kim, Joon Young Song, Jun Yong Choi, Yoon Soo Park   +12 more
openaire   +2 more sources

A Selective Medium for Screening Ceftazidime/Avibactam Resistance in Carbapenem-Resistant Enterobacterales

Frontiers in Microbiology, 2022
Ceftazidime/avibactam (CZA) is an alternative antibiotic used for the treatment of infections caused by carbapenem-resistant Enterobacterales (CRE). However, the CZA-resistant CRE strains have been detected worldwide. Therefore, it is critical to screen CZA-resistant CRE strains in colonized patients or a specific population so as to rapidly implement ...
Weiliang Zeng, Wenli Liao, Wenli Liao, Yajie Zhao, Lingbo Wang, Hongyun Shu, Huaiyu Jia, Tao Chen, Ying Zhang, Tieli Zhou, Qing Wu   +10 more
openaire   +3 more sources

In Vitro Antibacterial Activity of Imipenem/Relebactam against Clinical Isolates in Japan

Microbiology Spectrum, 2022
Relebactam is a novel β-lactamase inhibitor of Ambler class A and C β-lactamases that has been developed in combination with imipenem/cilastatin for the treatment of carbapenem-resistant bacterial infections.
Dai Kurihara, Satoru Matsumoto, Naoko Kishi, Yoshikazu Ishii, Masahiko Mori   +4 more
doaj   +1 more source