Results 81 to 90 of about 810,489 (200)

Focused Update to International Consensus Recommendations for the Use of Prolonged‐Infusion Beta‐Lactam Antibiotics Among Severely Ill Adult Patients: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Care Medicine, and Society of Infectious Diseases Pharmacists

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 9, September 2026.
ABSTRACT In 2023, international consensus recommendations suggested the use of prolonged‐infusion beta‐lactam antibiotics over short‐infusion dosing in severely ill adult patients to improve mortality or clinical cure, although the certainty of evidence was very low. With the availability of several new randomized controlled trials (RCTs), this focused
Lisa T. Hong, Alireza FakhriRavari, Marta Ulldemolins, Jason A. Roberts, Robert A. Bonomo, Marc H. Scheetz, on behalf of the Prolonged‐Infusion Beta‐Lactam Consensus Panel, Jacinda C. Abdul‐Mutakabbir, Mohammad H. Alshaer, Matteo Bassetti, Robert A. Bonomo, Kevin J. Downes, Alireza FakhriRavari, Mark Gilchrist, Lisa T. Hong, Jason A. Roberts, Marc H. Scheetz, Thomas Tängdén, Marta Ulldemolins, David C. Young   +19 more
wiley   +1 more source

mcr‐Mediated Colistin Resistance in Escherichia coli: A One Health Review of Reported Prevalence Across Human, Animal, Food, and Environmental Sectors

Public Health Challenges, Volume 5, Issue 3, September 2026.
This One Health review maps the global prevalence of mcr‐mediated colistin resistance in Escherichia coli across human, animal, food, and environmental sectors. By tracking datasets across diverse geographic regions, the study highlights critical resistance hotspots, emphasizing the urgent need for integrated cross‐sectoral surveillance to limit global
Ferdous‐Ul‐Haque Joy, Tashfiya Zaman Mouree, Munny Das, Asma Kabir   +3 more
wiley   +1 more source

Carbapenem-resistant genes primer sets.

, 2023
BackgroundCarbapenem-resistant Enterobacteriaceae (CRE) and Extended-spectrum beta-lactamase (ESBL) production among Gram-negative Enterobacteriaceae is an increasing global challenge due to the high morbidity and mortality associated with their ...
Frank Twum Aboagye (17304867), Alex Owusu-Ofori (5931680), Isaac Owusu-Frimpong (11047490), James Sampah (17304864)   +3 more
core   +1 more source

Selective Digestive Decontamination in Hemato-Oncological Patients Colonized with Carbapenem-Resistant Enterobacterales

Acta Médica Portuguesa
Infections caused by multidrug-resistant Gram-negative bacteria, including carbapenem-resistant Enterobacterales, are a global threat and their gradual increase is alarming.
Sara de Abreu Luís, Carla Mimoso Santos
doaj   +1 more source

A Lytic Bacteriophage Cocktail Attenuates Carbapenem‐Resistant Klebsiella pneumoniae–Acinetobacter baumannii Mixed‐Species Biofilms and Reshapes Transcriptional Responses

Microbial Biotechnology, Volume 19, Issue 9, September 2026.
A lytic phage cocktail targeting CRKP–CRAB mixed biofilms was systematically evaluated through in vitro, device‐associated, and in vivo models. Integrated transcriptomic analysis revealed molecular responses underlying biofilm disruption, providing mechanistic insights and experimental evidence supporting phage cocktails as a promising strategy against
Xuefang Ren, Rui Zhu, Yijiang Yang, Xiaojuan You, Liuxiang Wang, Guangyu Fu, Yehuan Zheng, Chunxia Wang, Zhentao Wang, Yongwei Li   +9 more
wiley   +1 more source

Real‐Life Study on Gilteritinib‐Related Infections (GilteRInf): An Italian SEIFEM Study

American Journal of Hematology, Volume 101, Issue 10, Page 2672-2676, October 2026.
Elisa Buzzatti, Irene Terrenato, Martina Tomassi, Federica Lessi, Sara Pezone, Cristina Papayannidis, Gianluca Martini, Fabio Forghieri, Luana Fianchi, Martina Quattrone, Nicola Fracchiolla, Claudio Fozza, Michela Abbenante, Anna Lina Piccioni, Davide Facchinelli, Claudia Maria Basilico, Caterina Buquicchio, Nicola Di Renzo, Monica Piedimonte, Maria Giovanna Cefalo, Daniele Armiento, Adriano Venditti, Alessandro Busca, Francesco Marchesi, Maria Ilaria Del Principe, Livio Pagano   +25 more
wiley   +1 more source

A Four‐Center Study on the Activity of Aztreonam and Aztreonam‐Avibactam Combination Against Clinical Isolates of Gram‐Negative Bacilli Producing Representatives of Ambler Class A, B, C or D β‐Lactamases

APMIS, Volume 134, Issue 9, September 2026.
ABSTRACT We aimed to investigate the activity of aztreonam and aztreonam‐avibactam combination against gram‐negative bacilli producing different types of β‐lactamases. Activity of aztreonam and aztreonam‐avibactam against 166 isolates (33 AmpC‐producing, 33 ESBL‐producing, 66 carbapenemase‐producing Enterobacterales, 34 metallo‐β‐lactamase‐producing P.
Gizem İnce Ceviz, Hasan Cenk Mirza, Aylin Üsküdar Güçlü, Özlem Öğüç Şanlı, Özlem Kurt Azap, Banu Sancak, Elvan Hortaç İştar, Ahmet Başustaoğlu   +7 more
wiley   +1 more source

Therapeutic options for carbapenem-resistant Enterobacteriaceae infections

, 2017
In recent years, carbapenem resistance among Enterobacteriaceae has dramatically increased and represents an important threat to global health. The optimal therapeutic management of carbapenem-resistant Enterobacteriaceae (CRE) infections has not been ...
Tumbarello, Mario, Trecarichi, Enrico Maria, Enrico Maria Trecarichi, Mario Tumbarello   +3 more
core   +1 more source

Awareness on the spread of carbapenem-resistant Enterobacterales in animals as One Health

Journal of Veterinary Science
One Health is a multisectoral cooperative and collaborative approach aimed at achieving integrated health by recognizing the interconnectedness of people, animals, plants, and the environment. In the modern world, the One Health approach is considered an essential perspective for overcoming various emerging diseases, including antimicrobial resistance (
Su Min Kyung, Han Sang Yoo
openaire   +2 more sources

Real-world use of eravacycline for the treatment of mono- and polymicrobial infections involving Enterobacterales

Microbiology Spectrum
Bacterial species in the Enterobacterales order are commonly encountered causative organisms in hospital-acquired infections. Furthermore, the incidence of carbapenem-resistant Enterobacterales (CRE) is a growing threat worldwide. Eravacycline (ERV) is a
Sean R. Van Helden, Ashlan J. Kunz Coyne, Sara Alosaimy, Abdalhamid M. Lagnf, Kyle C. Molina, S. Lena Kang-Birken, Kimberly C. Claeys, Mark Biagi, Justin Andrade, Alaina DeKerlegand, Melanie Rae Schrack, Tristan Gore, Madeline A. King, Benjamin M. Pullinger, Serina Tart, Athena L. V. Hobbs, Jazmin Agee, Nicholson B. Perkins, Michael P. Veve, Reese Cosimi, Shelbye R. Herbin, Bruce M. Jones, Amy K. Feehan Curley, Chloe Judd, Mohammed Al Musawa, Michael J. Rybak   +25 more
doaj   +1 more source