Results 1 to 10 of about 13,453 (147)

Carriage of K. pneumoniae and molecular structure of produced carbapenemases in infants with congenital heart defects [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2023
Objective. To evaluate frequency of pharyngeal and rectal mucosa colonization by K. pneumoniae strains in infants with congenital heart defects at the stage of cardiosurgical hospital admission, as well as dynamic analysis of production frequency and ...
Popov D.A., Osokina R.A., Vostrikova T.Yu.   +2 more
doaj   +1 more source

Expression analysis of drug-resistant gene (blaOXA-51) in carbapenemases producing Acinetobacter baumannii treated with imipenem/sulbactam combination

Brazilian Journal of Pharmaceutical Sciences, 2021
Drug-resistant Acinetobacter baumannii is a frightening reality. The aim of this study is to examine the expression profiles of blaOXA-51 gene in carbapenemases producing A. baumannii treated with imipenem/sulbactam combination.
Saber Noshadi, Alireza Khodavandi
doaj   +1 more source

Evaluation of Xpert Carba-R for detecting carbapenemase-producing organisms in South Africa

African Journal of Laboratory Medicine, 2023
This study evaluated the performance of the Xpert Carba-R assay for detecting the five common carbapenemases in carbapenemase-producing organisms in Johannesburg, South Africa between April 2021 and September 2021.
Sanelisiwe T. Duze, Teena Thomas, Tshegofatso Pelego, Sabelle Jallow, Olga Perovic, Adriano Duse   +5 more
doaj   +1 more source

Genetic Diversity, Biochemical Properties, and Detection Methods of Minor Carbapenemases in Enterobacterales

Frontiers in Medicine, 2021
Gram-negative bacteria, especially Enterobacterales, have emerged as major players in antimicrobial resistance worldwide. Resistance may affect all major classes of anti-gram-negative agents, becoming multidrug resistant or even pan-drug resistant ...
Rémy A. Bonnin, Rémy A. Bonnin, Rémy A. Bonnin, Agnès B. Jousset, Agnès B. Jousset, Agnès B. Jousset, Agnès B. Jousset, Cécile Emeraud, Cécile Emeraud, Cécile Emeraud, Cécile Emeraud, Saoussen Oueslati, Saoussen Oueslati, Laurent Dortet, Laurent Dortet, Laurent Dortet, Laurent Dortet, Thierry Naas, Thierry Naas, Thierry Naas, Thierry Naas   +20 more
doaj   +1 more source

Carbapenemases as factors of Resistance to Antibacterial Drugs

Acta Biomedica Scientifica, 2021
Antibiotic drugs are used to treat and prevent bacterial infections around the world. The emergence and spread of  bacterial resistance to carbapenems is currently a real threat that determines the need for its timely detection and  suppression ...
A. V. Nevezhina
doaj   +1 more source

Comparative Activity of Carbapenem Antibiotics Against Gram-Negative Carbapenemase Producers of Different Groups

Антибиотики и Химиотерапия, 2022
The rapid spread of gram-negative bacteria resistance to carbapenems due to the production of carbapenemases requires new treatment options. The activity of carbapenem antibiotic biapenem, recently registered in Russia, against producers of various ...
V. A. Ageevets, O. S. Sulian, A. A. Avdeeva, P. S. Chulkova, V. V. Gostev, I. V. Ageevets, M. V. Golikova, K. N. Alieva, D. P. Gladin, S. V. Sidorenko   +9 more
doaj   +1 more source

In vitro activity of ceftazidime/avibactam and comparators against carbapenemase-producing Enterobacterales and Pseudomonas aeruginosa isolates collected globally between 2016 and 2018

Journal of Global Antimicrobial Resistance, 2021
: Objectives: This study reports the antimicrobial activity of ceftazidime/avibactam (CZA) and comparators against carbapenemase-producing Enterobacterales (N = 1992) and carbapenemase-producing Pseudomonas aeruginosa (N = 784) collected in Africa/Middle
Pattarachai Kiratisin, Krystyna Kazmierczak, Gregory G. Stone   +2 more
doaj   +1 more source

Infections Caused by Carbapenem-Resistant Enterobacterales: Epidemiology, Clinical Significance, and Possibilities for Antibiotic Therapy Optimization

Антибиотики и Химиотерапия, 2020
The resistance of Enterobacterales to carbapenems can be realized by different mechanisms, but the most common one is enzymatic, associated with the production of carbapenemases.
S. V. Yakovlev, M. P. Suvorova, A. O. Bykov   +2 more
doaj   +1 more source

OXA-type carbapenemases in Acinetobacter baumannii in South America

Journal of Infection in Developing Countries, 2011
Acinetobacter baumannii is an opportunistic pathogen that is frequently involved in outbreaks of infection, occurring mostly in intensive care units. The increasing incidence of carbapenem resistance in A.
Andrés Opazo, Mariana Domínguez, Helia Bello, Sebastian G.B. Amyes, Gerardo González-Rocha   +4 more
doaj   +1 more source

Molecular diversity of extended-spectrum β-lactamases and carbapenemases, and antimicrobial resistance

Journal of Intensive Care, 2020
Along with the recent spread of multidrug-resistant bacteria, outbreaks of extended-spectrum β-lactamase (ESBL) and carbapenemase-producing bacteria present a serious challenge to clinicians.
Teiji Sawa, Kunihiko Kooguchi, Kiyoshi Moriyama   +2 more
doaj   +1 more source