Results 1 to 10 of about 43,420 (302)
Structural and Functional Aspects of Class A Carbapenemases. [PDF]
Current Drug Targets, 2016 The fight against infectious diseases is probably one of the greatest public health challenges faced by our society, especially with the emergence of carbapenem-resistant gram-negatives that are in some cases pan-drug resistant.
Dortet, L, Iorga, BI, Naas, T
core +10 more sources
Frontiers in Medicine, 2021 Gram-negative bacteria, especially Enterobacterales, have emerged as major players in antimicrobial resistance worldwide. Resistance may affect all major classes of anti-gram-negative agents, becoming multidrug resistant or even pan-drug resistant ...
Rémy A. Bonnin +20 more
doaj +2 more sources
Journal of Intensive Care, 2020 Along with the recent spread of multidrug-resistant bacteria, outbreaks of extended-spectrum β-lactamase (ESBL) and carbapenemase-producing bacteria present a serious challenge to clinicians.
Teiji Sawa +2 more
doaj +2 more sources
Antibiotics, 2020 The Enterobacteriales order consists of seven families including Enterobacteriaceae, Erwiniaceae, Pectobacteriaceae, Yersiniaceae, Hafniaceae, Morganellaceae, and Budviciaceae and 60 genera encompassing over 250 species.
Gurleen Taggar +3 more
doaj +2 more sources
Comparative analysis of selected methods of carbapenemase determination among clinical Klebsiella pneumoniae. [PDF]
PLoS ONEKlebsiella pneumoniae is a typical opportunistic pathogen that exhibits multiple virulence factors and antibiotic resistance conditioning mechanisms. Carbapenemases are enzymes that help bacteria to exhibit the strongest resistance against antibiotics ...
Agata Pruss +9 more
doaj +2 more sources
Epidemiology and Genetic Traits of Carbapenemase-Producing Enterobacterales: A Global Threat to Human Health [PDF]
AntibioticsCarbapenemase-producing Enterobacterales (CPE) represent an important threat to global health, resulting in an urgent issue in clinical settings. CPE often exhibit a multidrug-resistant (MDR) phenotype, thus reducing the antimicrobial armamentarium, with
Gualtiero Alvisi +7 more
doaj +2 more sources
OXA-48-like carbapenemases in the UK: an analysis of isolates and cases from 2007 to 2014 [PDF]
Journal of Antimicrobial Chemotherapy, 2017 Objectives: OXA-48-like carbapenemases have spread worldwide since 2001. We analysed patient and microbiological data for UK isolates with these enzymes as confirmed by the national reference laboratory from November 2007 - December 2014.
Doumith, Michel +9 more
core +2 more sources
Carriage of K. pneumoniae and molecular structure of produced carbapenemases in infants with congenital heart defects [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2023 Objective. To evaluate frequency of pharyngeal and rectal mucosa colonization by K. pneumoniae strains in infants with congenital heart defects at the stage of cardiosurgical hospital admission, as well as dynamic analysis of production frequency and ...
Popov D.A. +2 more
doaj +1 more source
Brazilian Journal of Pharmaceutical Sciences, 2021 Drug-resistant Acinetobacter baumannii is a frightening reality. The aim of this study is to examine the expression profiles of blaOXA-51 gene in carbapenemases producing A. baumannii treated with imipenem/sulbactam combination.
Saber Noshadi, Alireza Khodavandi
doaj +1 more source
Carbapenemases as factors of Resistance to Antibacterial Drugs
Acta Biomedica Scientifica, 2021 Antibiotic drugs are used to treat and prevent bacterial infections around the world. The emergence and spread of bacterial resistance to carbapenems is currently a real threat that determines the need for its timely detection and suppression ...
A. V. Nevezhina
doaj +1 more source