Results 11 to 20 of about 19,967 (214)

Carbapenemase-Producing Enterobacteriaceae [PDF]

open access: yesSeminars in Respiratory and Critical Care Medicine, 2015
Carbapenemase-producing Enterobacteriaceae (CPE) were almost nonexistent up to the 1990s, but are today encountered routinely in hospitals and other healthcare facilities in many countries including the United States. KPC-producing Klebsiella pneumoniae was the first to emerge and spread globally and is endemic in the United States, Israel, Greece, and
Doi, Yohei, Paterson, David L.
openaire   +3 more sources

Infections Caused by Carbapenem-Resistant Enterobacterales: Epidemiology, Clinical Significance, and Possibilities for Antibiotic Therapy Optimization

open access: yesАнтибиотики и Химиотерапия, 2020
The resistance of Enterobacterales to carbapenems can be realized by different mechanisms, but the most common one is enzymatic, associated with the production of carbapenemases.
S. V. Yakovlev   +2 more
doaj   +1 more source

OXA-type carbapenemases [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2006
In recent years, the number of class D beta-lactamases with carbapenem-hydrolysing properties has increased substantially. Based on amino acid sequence identities, these class D or OXA-type carbapenemases are divided into eight distantly related groups, and they are only remotely related to other class D beta-lactamases.
Walther-Rasmussen, J., Høiby, Niels
openaire   +2 more sources

Carbapenemase-producing Klebsiella pneumoniae [PDF]

open access: yesF1000Prime Reports, 2014
The continuing emergence of infections due to multidrug resistant bacteria is a serious public health problem. Klebsiella pneumoniae, which commonly acquires resistance encoded on mobile genetic elements, including ones that encode carbapenemases, is a prime example. K. pneumoniae carrying such genetic material, including both blaKPC and genes encoding
Robilotti, Elizabeth, Deresinski, Stan
openaire   +2 more sources

OXA-type carbapenemases in Acinetobacter baumannii in South America

open access: yesJournal of Infection in Developing Countries, 2011
Acinetobacter baumannii is an opportunistic pathogen that is frequently involved in outbreaks of infection, occurring mostly in intensive care units. The increasing incidence of carbapenem resistance in A.
Andrés Opazo   +4 more
doaj   +1 more source

Molecular diversity of extended-spectrum β-lactamases and carbapenemases, and antimicrobial resistance

open access: yesJournal of Intensive Care, 2020
Along with the recent spread of multidrug-resistant bacteria, outbreaks of extended-spectrum β-lactamase (ESBL) and carbapenemase-producing bacteria present a serious challenge to clinicians.
Teiji Sawa   +2 more
doaj   +1 more source

Carbapenemases: the Versatile β-Lactamases [PDF]

open access: yesClinical Microbiology Reviews, 2007
SUMMARYCarbapenemases are β-lactamases with versatile hydrolytic capacities. They have the ability to hydrolyze penicillins, cephalosporins, monobactams, and carbapenems. Bacteria producing these β-lactamases may cause serious infections in which the carbapenemase activity renders many β-lactams ineffective.
Anne Marie, Queenan, Karen, Bush
openaire   +2 more sources

Impact of Hospital Wastewater on the Occurrence and Diversity of Beta-Lactamase Genes During Wastewater Treatment with an Emphasis on Carbapenemase Genes: A Metagenomic Approach

open access: yesFrontiers in Environmental Science, 2021
The diversity of beta-lactam antibiotic resistance genes, with particular emphasis on carbapenemase genes, during the treatment process at two wastewater treatment plants (WWTPs) with different levels of hospital wastewater inflow was investigated using ...
Jakub Hubeny   +6 more
doaj   +1 more source

CARB-ES-19 Multicenter Study of Carbapenemase-Producing Klebsiella pneumoniae and Escherichia coli From All Spanish Provinces Reveals Interregional Spread of High-Risk Clones Such as ST307/OXA-48 and ST512/KPC-3

open access: yesFrontiers in Microbiology, 2022
ObjectivesCARB-ES-19 is a comprehensive, multicenter, nationwide study integrating whole-genome sequencing (WGS) in the surveillance of carbapenemase-producing K. pneumoniae (CP-Kpn) and E.
Javier E. Cañada-García   +128 more
doaj   +1 more source

Rapid Detection of Carbapenemase and Extended-Spectrum β-Lactamase Producing Gram-Negative Bacteria Directly from Positive Blood Cultures Using a Novel Protocol

open access: yesAntibiotics, 2022
Background: Early and adequate antibiotic treatment is the cornerstone of improving clinical outcomes in patients with bloodstream infections (BSI).
Diego Fernando Josa   +12 more
doaj   +1 more source

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