Results 21 to 30 of about 43,420 (302)
Infection and Drug Resistance, 2022 Carbapenemases are β-lactamase enzymes that hydrolyze a variety of β-lactams including carbapenem and belong to different Ambler classes (A, B, D). These enzymes can be encoded by plasmid or chromosomal-mediated genes.
Neetu Gupta +2 more
semanticscholar +1 more source
Journal of Global Antimicrobial Resistance, 2021 : Objectives: This study reports the antimicrobial activity of ceftazidime/avibactam (CZA) and comparators against carbapenemase-producing Enterobacterales (N = 1992) and carbapenemase-producing Pseudomonas aeruginosa (N = 784) collected in Africa/Middle
Pattarachai Kiratisin +2 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2020 This study aimed to investigate the dissemination and characteristics of blaKPC, blaNDM, blaOXA-48-like, blaIMP, and blaVIM among the carbapenem-resistant Enterobacteriaceae (CRE) strains isolated from adult and children patients.
Renru Han +9 more
semanticscholar +1 more source
Антибиотики и Химиотерапия, 2020 The resistance of Enterobacterales to carbapenems can be realized by different mechanisms, but the most common one is enzymatic, associated with the production of carbapenemases.
S. V. Yakovlev +2 more
doaj +1 more source
Carbapenemase-Producing Enterobacteriaceae [PDF]
Seminars in Respiratory and Critical Care Medicine, 2015 Carbapenemase-producing Enterobacteriaceae (CPE) were almost nonexistent up to the 1990s, but are today encountered routinely in hospitals and other healthcare facilities in many countries including the United States. KPC-producing Klebsiella pneumoniae was the first to emerge and spread globally and is endemic in the United States, Israel, Greece, and
Doi, Yohei, Paterson, David L.
openaire +4 more sources
Detection of Multidrug-Resistant Enterobacterales—From ESBLs to Carbapenemases
Antibiotics, 2021 Multidrug-resistant Enterobacterales (MDRE) are an emerging threat to global health, leading to rising health care costs, morbidity and mortality.
Janina Noster, P. Thelen, A. Hamprecht
semanticscholar +1 more source
Antibiotics, 2020 Carbapenemases are β-lactamases belonging to different Ambler classes (A, B, D) and can be encoded by both chromosomal and plasmid-mediated genes.
Dalal Hammoudi Halat, C. Ayoub Moubareck
semanticscholar +1 more source
Journal of Antimicrobial Chemotherapy, 2006 In recent years, the number of class D beta-lactamases with carbapenem-hydrolysing properties has increased substantially. Based on amino acid sequence identities, these class D or OXA-type carbapenemases are divided into eight distantly related groups, and they are only remotely related to other class D beta-lactamases.
Walther-Rasmussen, J., Høiby, Niels
openaire +3 more sources
Difference in Susceptibility Between Carbapenemase- and Non–Carbapenemase-Producing Carbapenem-Resistant Enterobacteriaceae [PDF]
Antimicrobial Stewardship & Healthcare Epidemiology, 2021 Background: Carbapenem-resistant Enterobacteriaceae (CRE) remain among the most urgent infectious threats according to the CDC Threats Reports. Although focus has often been placed on carbapenemase-producing phenotypes, there is increasing interest in distinguishing the optimal treatment and outcomes of carbapenemase-producing (CP) and non ...
Justin A. Clark, David S. Burgess
openaire +2 more sources
Msphere, 2021 Neonatal sepsis is a leading cause of neonatal mortality in low- and middle-income countries (LMICs). Treatment of sepsis in this vulnerable population is dependent on antimicrobials, and resistance to these life-saving antimicrobials is worrisome ...
S. Naha +5 more
semanticscholar +1 more source