Results 31 to 40 of about 43,420 (302)
Escalating antimicrobial resistance among Enterobacteriaceae: focus on carbapenemases
Expert Opinion on Pharmacotherapy, 2021 Introduction: Over the past few decades, antimicrobial resistance (AMR) has skyrocketed globally among bacteria within the Family Enterobacteriaceae (i.e.
J. Lynch, N. Clark, G. Zhanel
semanticscholar +1 more source
Phosphonopeptides Revisited, in an Era of Increasing Antimicrobial Resistance [PDF]
, 2020 Given the increase in resistance to antibacterial agents, there is an urgent need for the development of new agents with novel modes of action. As an interim solution, it is also prudent to reinvestigate old or abandoned antibacterial compounds to assess
Anderson, Rosaleen +8 more
core +2 more sources
Rapid Broad Spectrum Detection of Carbapenemases with a Dual Fluorogenic-Colorimetric Probe.
Journal of the American Chemical Society, 2021 Carbapenems stand as one of the last-resort antibiotics; however, their efficacy is threatened by the rising number and rapid spread of carbapenemases.
Chi-Wang Ma +5 more
semanticscholar +1 more source
Carbapenemase-producing Klebsiella pneumoniae [PDF]
F1000Prime Reports, 2014 The continuing emergence of infections due to multidrug resistant bacteria is a serious public health problem. Klebsiella pneumoniae, which commonly acquires resistance encoded on mobile genetic elements, including ones that encode carbapenemases, is a prime example. K. pneumoniae carrying such genetic material, including both blaKPC and genes encoding
Elizabeth Robilotti, Stan Deresinski
openaire +3 more sources
Frontiers in Microbiology, 2022 ObjectivesCARB-ES-19 is a comprehensive, multicenter, nationwide study integrating whole-genome sequencing (WGS) in the surveillance of carbapenemase-producing K. pneumoniae (CP-Kpn) and E.
Javier E. Cañada-García +128 more
doaj +1 more source
Carbapenemases: Transforming Acinetobacter baumannii into a Yet More Dangerous Menace
Biomolecules, 2020 Acinetobacter baumannii is a common cause of serious nosocomial infections. Although community-acquired infections are observed, the vast majority occur in people with preexisting comorbidities. A. baumannii emerged as a problematic pathogen in the 1980s
M. Ramírez, R. Bonomo, M. Tolmasky
semanticscholar +1 more source
Antibiotics, 2022 Background: Early and adequate antibiotic treatment is the cornerstone of improving clinical outcomes in patients with bloodstream infections (BSI).
Diego Fernando Josa +12 more
doaj +1 more source
Mobile Carbapenemase Genes in Pseudomonas aeruginosa [PDF]
Frontiers in Microbiology, 2021 Carbapenem-resistantPseudomonas aeruginosais one of the major concerns in clinical settings impelling a great challenge to antimicrobial therapy for patients with infections caused by the pathogen. While membrane permeability, together with derepression of the intrinsic beta-lactamase gene, is the global prevailing mechanism of carbapenem resistance ...
Seok Hoon Jeong, Eun Jeong Yoon
openaire +5 more sources
Severe bloodstream infection due to KPC-producer e coli in a renal transplant recipient treated with the double-carbapenem regimen and analysis of in vitro synergy testing a case report [PDF]
, 2016 Transplant recipients are at high risk of infections caused by multidrug resistant microorganisms. Due to the limited thera- peutic options, innovative antimicrobial combinations against carbape- nem-resistant Enterobacteriaceae causing severe infections
CIPOLLA, ALESSIA +11 more
core +1 more source
Infection and Drug Resistance, 2021 Background and Aim The extended-spectrum beta-lactamases (ESBLs), as well as carbapenemases, are considered as the foremost resistance determinants throughout the world.
S. Ilyas +6 more
semanticscholar +1 more source