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The Preferred Conformation of Oligosaccharides Derived from the Complex‐Type Carbohydrate Portions of Glycoproteins [PDF]

open access: bronzeEuropean Journal of Biochemistry, 1982
The preferred conformation in aqueous solution of oligosaccharides related to the complex-type carbohydrate portion of glycoproteins has been inferred from high-resolution nuclear magnetic resonance data (both 1H and 13C) combined with hard-sphere exo ...
Klaus Bock   +2 more
openalex   +2 more sources

Isolation and characterization of conformation sensitive antierythropoietin monoclonal antibodies: effect of disulfide bonds and carbohydrate on recombinant human erythropoietin structure [PDF]

open access: bronzeBlood, 1996
We have isolated and characterized three anti-recombinant human erythropoietin (rHuEPO) monoclonal antibodies (MoAbs) that recognize nonoverlapping epitopes on rHuEPO. Anti-EPO MoAb D11 neutralizes rHuEPO activity whereas MoAbs F12 and 9G8A do not.
Steve Elliott   +8 more
openalex   +2 more sources

Acetyl α-d-2,3,4-triacetyllyxopyranoside [PDF]

open access: yesIUCrData
The structure of the title compound, C13H18O9, has monoclinic (P21) symmetry. It is of interest with respect to stereochemistry and the anomeric effect. Two acetyl subsituents adopt equatorial orientations and two are axial.
Shawn Culver, Jonathan S. Rhoad
doaj   +2 more sources

Enhanced conformational sampling of carbohydrates by Hamiltonian replica-exchange simulation [PDF]

open access: bronzeGlycobiology, 2013
Knowledge of the structure and conformational flexibility of carbohydrates in an aqueous solvent is important to improving our understanding of how carbohydrates function in biological systems. In this study, we extend a variant of the Hamiltonian replica-exchange molecular dynamics (MD) simulation to improve the conformational sampling of saccharides ...
Mahmut Kara   +4 more
openaire   +6 more sources

Approximate quantum chemical methods for modelling carbohydrate conformation and aromatic interactions: β-cyclodextrin and its adsorption on a single-layer graphene sheet

open access: greenPhysical Chemistry, Chemical Physics - PCCP, 2017
Noncovalent functionalization of graphene by carbohydrates such as β-cyclodextrin (βCD) has the potential to improve graphene dispersibility and its use in biomedical applications.
Panichakorn Jaiyong, Richard A. Bryce
openalex   +3 more sources

Conformational studies on the N‐linked carbohydrate chain of bromelain [PDF]

open access: bronzeEuropean Journal of Biochemistry, 1990
1H‐ and 13C‐NMR assignments for the carbohydrate part of the glycopeptide α‐d‐Man‐(1→6)‐[ß‐d‐Xyl‐(1→2)]‐ß‐d‐Man‐(1→4)‐ß‐d‐GlcNAc‐(1→4)‐[α‐l‐Fuc‐(1→3)]‐ß‐d‐ GlcNAc‐(1→N)‐Asn∼, derived from the proteolytic enzyme bromelain (EC 3.4.22.4), have been obtained using homo‐ and heteronuclear correlation spectroscopy, two‐dimensional homonuclear Hartmann‐Hahn ...
Vliegenthart, J.F.G.   +5 more
openaire   +6 more sources

Protecting Groups in Carbohydrate Chemistry: Influence on Stereoselectivity of Glycosylations

open access: yesMolecules, 2010
Saccharides are polyhydroxy compounds, and their synthesis requires complex protecting group manipulations. Protecting groups are usually used to temporarily mask a functional group which may interfere with a certain reaction, but protecting groups in ...
Jian Guo, Xin-Shan Ye
doaj   +2 more sources

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