Results 91 to 100 of about 109,847 (333)

Cucurbit[7]uril‐Styryl Dye Complexes for Fluorescent Recognition of DNA and Cell Imaging

ChemBioChem, EarlyView.
Recognition properties in solution and in cancer cells: a two dicationic cyanine dyes with different functionalities were developed and studied for their fluorescent properties, cytotoxicity and cellular imaging. The effect of encapsulation was checked using synthetic molecular container of cucurbit[7]uril.
Ekaterina Y. Chernikova, Maria A. Ustimova, Yuri V. Fedorov, Polina A. Chernikova, Ivan A. Godovikov, Nelly S. Chmelyuk, Maxim A. Abakumov, Olga A. Fedorova   +7 more
wiley   +1 more source

SEC‐SAXS/MC Ensemble Structural Studies of the Microtubule Binding Protein Cdt1 Show Monomeric, Folded‐Over Conformations

Cytoskeleton, EarlyView.
ABSTRACT Cdt1 is a mixed folded protein critical for DNA replication licensing and it also has a “moonlighting” role at the kinetochore via direct binding to microtubules and the Ndc80 complex. However, it is unknown how the structure and conformations of Cdt1 could allow it to participate in these multiple, unique sets of protein complexes.
Kyle P. Smith, Srinivas Chakravarthy, Amit Rahi, Manas Chakraborty, Kristen M. Vosberg, Marco Tonelli, Maximilian G. Plach, Arabela A. Grigorescu, Joseph E. Curtis, Dileep Varma   +9 more
wiley   +1 more source

Bilateral Intravitreal Dexamethasone Implant for Retinitis Pigmentosa-Related Macular Edema

Case Reports in Ophthalmology, 2013
Purpose: To report the efficacy of intravitreal dexamethasone implant in a patient with retinitis pigmentosa and bilateral cystoid macular edema unresponsive to topical carbonic anhydrase inhibitors.
Ali Osman Saatci, Ozlem Barut Selver, Goktug Seymenoglu, Aylin Yaman   +3 more
doaj   +1 more source

Synthesis, molecular modelling and QSAR study of new N-phenylacetamide-2-oxoindole benzensulfonamide conjugates as carbonic anhydrase inhibitors with antiproliferative activity

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
In continuation of our previous studies to optimise potent carbonic anhydrase inhibitors, two new series of isatin N-phenylacetamide based sulphonamides were synthesised and screened for their human (h) carbonic anhydrase (EC 4.2.1.1) inhibitory ...
Mona F. Said, Riham F. George, Andrea Petreni, Claudiu T. Supuran, Nada M. Mohamed   +4 more
doaj   +1 more source

Electron capture decay of indium-111 human carbonic anhydrase I: A time differential K X ray coincidence perturbed angular correlation study [PDF]

arXiv, 2003
The relaxation effects in the perturbed angular correlation spectra of indium-111 human carbonic anhydrase I (HCA I) are the result of chemical transmutation and/or the complex Auger cascades that follow the electron capture decay of indium-111. Time differential K X ray coincidence perturbed angular correlation (PAC) spectroscopy shows that these ...
arxiv  

Continuous Titration Based Method for Rapid In‐Solution Analysis of Non‐Covalent Interactions

Chemistry–Methods, EarlyView.
This work presents cSPRING, which combines Taylor dispersion with ratiometric fluorescence detection to measure binding affinities (Kd) in a single experiment. This in‐solution method reduces sample preparation time 8‐fold, requires only nanograms of protein, and provides results in under a minute, demonstrating efficiency for screening protein‐small ...
Philipp Willmer, Adam C. Hundahl, Rodolphe Marie, Henrik Jensen   +3 more
wiley   +1 more source

The lifetime of the oxygen‐evolving complex subunit PSBO depends on light intensity and carbon availability in Chlamydomonas

Plant, Cell &Environment, Volume 46, Issue 2, Page 422-439, February 2023., 2023
Abstract PSBO is essential for the assembly of the oxygen‐evolving complex in plants and green algae. Despite its importance, we lack essential information on its lifetime and how it depends on the environmental conditions. We have generated nitrate‐inducible PSBO amiRNA lines in the green alga Chlamydomonas reinhardtii.
André Vidal‐Meireles, Soujanya Kuntam, Eszter Széles, Dávid Tóth, Juliane Neupert, Ralph Bock, Szilvia Z. Tóth   +6 more
wiley   +1 more source

Numeric modeling of fire suppression by organophosphorous inhibitors [PDF]

arXiv, 2008
Numerical calculations of the effect of organophosphorous inhibitor (CF3CH2O)3P and its mixtures with carbon dioxide on propane flames are carried out using the three dimensional Reynolds-averaged Navier-Stokes (RANS) equations in the low Mach number approximation. The k-e model of turbulence, the EDC combustion model and the weighted-sum-of-gray-gases
arxiv  

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

Drug Testing and Analysis, EarlyView.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis, Tiia  Kuuranne, Hans  Geyer   +2 more
wiley   +1 more source

Structural Basis for the Inhibition of Helicobacter pylori α-Carbonic Anhydrase by Sulfonamides. [PDF]

PLoS ONE, 2015
Periplasmic α-carbonic anhydrase of Helicobacter pylori (HpαCA), an oncogenic bacterium in the human stomach, is essential for its acclimation to low pH. It catalyses the conversion of carbon dioxide to bicarbonate using Zn(II) as the cofactor.
Joyanta K Modak, Yu C Liu, Mayra A Machuca, Claudiu T Supuran, Anna Roujeinikova   +4 more
doaj   +1 more source