Results 81 to 90 of about 695,880 (253)
Bilateral Intravitreal Dexamethasone Implant for Retinitis Pigmentosa-Related Macular Edema
Case Reports in Ophthalmology, 2013 Purpose: To report the efficacy of intravitreal dexamethasone implant in a patient with retinitis pigmentosa and bilateral cystoid macular edema unresponsive to topical carbonic anhydrase inhibitors.
Ali Osman Saatci +3 more
doaj +1 more source
Investigation of Bacterial Carbonic Anhydrase Stability
, 2020 The purpose of this study was to investigate the stability of Bartonella henselae carbonic anhydrase in an effort to design screening methods for potential inhibitors.
Sutaria, Yatri
core
Photo‐responsive carbon dots for pyroptosis‐mediated anti‐tumor application
Responsive Materials, EarlyView.Photo‐responsive CDs generate ROS to induce tumor cell pyroptosis, thereby stimulating antitumor immunity. Abstract Pyroptosis refers to a kind of lytic programmed cell death, characterized by the release of pro‐inflammatory cytokines during the process. Owing to its immune response stimulation ability, pyroptosis has garnered considerable attention in
Lingyun Li +5 more
wiley +1 more source
, 1988 Multinuclear NMR and Vibrational Spectroscopy Studies of the Substituent Effects in Benzensulfonamide Inhibitors of the Enzyme Carbonic ...
BENEDETTI, Adriano +4 more
core +1 more source
A Cytoplasmic pH Sensor Redefines Gating in Bacterial Urea Channels and Acid Resistance
Small, EarlyView.Bacterial survival in acidic environments requires pH‐gated urea channels. Utilizing complementary approaches, we identify a conserved cytoplasmic glutamic acid residue as a pH sensor in UreI channels. Whereas Gram‐positive bacteria rely solely on this sensor, Gram‐negative bacteria employ a dual‐sensor mechanism with periplasmic residues, revealing a ...
Anna Stoib +10 more
wiley +1 more source
Structure-based drug design of novel inhibitors of carbonic anhydrase for treatment of glaucoma
, 2009 In humans, there are twelve carbonic anhydrase (CA) isozymes that possess catalytic activity for the reversible hydration of carbon dioxide. Carbonic anhydrases (CAs) underpin crucial physiological and pathological processes and are thus pharmaceutical ...
Singer, Mathilde +4 more
core
SOME IN VITRO INHIBITORS OF CARBONIC ANHYDRASE
, 1958 Work on sulphonamides as in vitro inhibitors of carbonic anhydrase has been extended by the preparation and assay of novel types. Although diphenylsulphonamides, p-alkoxycarbonylbenzene sulphonamides and 5-alkoxycarbonylamino-1:3:4-thiadiazole-2-sulphon ...
V Petrow +3 more
core +1 more source
Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments
Smart Molecules, EarlyView.Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu +7 more
wiley +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2018 Background & Aims: Human enteroids present a novel tool to study human intestinal ion transport physiology and pathophysiology. The present study describes the contributions of Cl- and HCO3- secretion to total cyclic adenosine monophosphate (cAMP ...
Jianyi Yin +6 more
doaj +1 more source
Allergy, EarlyView.This study established a microarray containing a representative panel of purified Blo t and Der p allergens for the identification of patients sensitised to Blo t and/or Der p. Results indicate that the microarray based on Blo t and Der p allergens is a useful tool for the identification of Blo t‐ and/or Der p‐sensitised patients. The microarray may be
Nishelle Dsouza +16 more
wiley +1 more source