The Redundancy of Peptidoglycan Carboxypeptidases Ensures Robust Cell Shape Maintenance in
mBio, 2016 Peptidoglycan (PG) is an essential structural component of the bacterial cell wall and maintains the integrity and shape of the cell by forming a continuous layer around the cytoplasmic membrane.
Katharina Peters +8 more
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Modulation of Peptidoglycan Synthesis by Recycled Cell Wall Tetrapeptides
Cell Reports, 2020 Summary: The bacterial cell wall is made of peptidoglycan (PG), a polymer that is essential for the maintenance of cell shape and survival. During growth, bacteria remodel their PG, releasing fragments that are predominantly re-internalized and recycled.
Sara B. Hernández +3 more
doaj +1 more source
The new effector AbSCP1 of foliar nematode (Aphelenchoides besseyi) is required for parasitism rice
Journal of Integrative Agriculture, 2022 Plant parasitic nematodes secrete effector proteins to parasitize hosts successfully. Of these proteins, serine carboxypeptidases have critical roles in pathogenicity.
Xin HUANG +5 more
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The effects of daptomycin on cell wall biosynthesis in Enterococcal faecalis
Scientific Reports, 2023 Daptomycin is a cyclic lipodepsipeptide antibiotic reserved for the treatment of serious infections by multidrug-resistant Gram-positive pathogens. Its mode of action is considered to be multifaceted, encompassing the targeting and depolarization of ...
Binayak Rimal +5 more
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[51] Exocellular dd-carboxypeptidases-transpeptidases from Streptomyces [PDF]
, 1976 peer reviewedStrains R39 and R61 are soil isolates. Their designations are arbitrary. In strain R39, the cross-link between the peptide units of the wall peptidoglycan extends from the C-terminal D-alanine of one unit to the amino group at the D-center ...
Ghuysen, Jean-Marie +9 more
core +1 more source
Antibiotics, 2016 The Gram-positive bacterium Staphylococcus carnosus (S. carnosus) TM300 is an apathogenic staphylococcal species commonly used in meat starter cultures.
Julia Deibert +4 more
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Understanding the constitutive presentation of MHC class I immunopeptidomes in primary tissues
iScience, 2022 Summary: Understanding the molecular principles that govern the composition of the MHC-I immunopeptidome across different primary tissues is fundamentally important to predict how T cells respond in different contexts in vivo. Here, we performed a global
Peter Kubiniok +13 more
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Glutamylation of an HIV-1 protein inhibits the immune response by hijacking STING
Cell Reports, 2023 Summary: Cyclic GMP-AMP synthase (cGAS) recognizes Y-form cDNA of human immunodeficiency virus type 1 (HIV-1) and initiates antiviral immune response through cGAS-stimulator of interferon genes (STING)-TBK1-IRF3-type I interferon (IFN-I) signalingcascade.
Gui Qian +17 more
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BRS1 mediates plant redox regulation and cold responses
BMC Plant Biology, 2021 Background Brassinosteroid-insensitive 1 suppressor 1 (BRS1) is a serine carboxypeptidase that mediates brassinosteroid signaling and participates in multiple developmental processes in Arabidopsis. However, little is known about the precise role of BRS1
Dongzhi Zhang +4 more
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Selective Cytotoxicity of Carboxypeptidase-activated Methotrexate ex-Peptides
Pteridines, 1989 Methotrexate ex-pep tides (derivatives in which an amino acid is linked covalently to the ex-carboxyl of the glutamate residue on the parent drug) can be hydrolyzed by specific carboxypeptidases to yield free Methotrexate (MTX) and the corresponding ...
Vitols Karin S. +3 more
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