Results 81 to 90 of about 23,292 (261)

Utility of SUVmax on Primary Staging 68Ga‐PSMA PET in Determining Metastatic Status of Prostate Cancer

open access: yesJournal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction 68Ga prostate‐specific membrane antigen (PSMA) has been shown to have prognostic value in detecting PSMA expressing metastasis from prostate cancer, but inevitably, there are cases in which suspected metastases demonstrate equivocal uptake.
Geoffrey Liu, Shane Lee, Kabir Ahmad
wiley   +1 more source

Characterisation of early metazoan secretion through associated signal peptidase complex subunits, prohormone convertases and carboxypeptidases of the marine sponge (Amphimedon queenslandica).

open access: yesPLoS ONE, 2019
Efficient communication between cells requires the ability to process precursor proteins into their mature and biologically active forms, prior to secretion into the extracellular space. Eukaryotic cells achieve this via a suite of enzymes that involve a
Michael J Hammond   +2 more
doaj   +1 more source

Mediation of Polygenic Asthma Risk Through Gene Expression

open access: yesAllergy, EarlyView.
We apply published PRSs in African‐ancestry individuals and quantify the extent to which the PRS‐asthma relationship is mediated by clinical biomarkers and gene‐expression signatures of asthma. We found the best PRS to be the one derived using the largest sample size and including African‐ancestry individuals.
Rakesh Natarajan   +29 more
wiley   +1 more source

Plasticity in the Oxidative Folding Pathway of the High Affinity Nerita Versicolor Carboxypeptidase Inhibitor (NvCI)

open access: yesScientific Reports, 2017
Nerita Versicolor carboxypeptidase inhibitor (NvCI) is the strongest inhibitor reported so far for the M14A subfamily of carboxypeptidases. It comprises 53 residues and a protein fold composed of a two-stranded antiparallel β sheet connected by three ...
Sebastián A. Esperante   +5 more
doaj   +1 more source

Digestive Enzymes of the Crustaceans Munida and Their Application in Cheese Manufacturing: A Review

open access: yesMarine Drugs, 2011
Crustaceans Munida (fam. Galatheideae, ord. Decapodi) were fished in the Southern Adriatic Sea and their proteolytic activities were characterized and tested for potential application in cheese manufacturing.
Rocco Rossano   +2 more
doaj   +1 more source

The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria

open access: yesAllergy, EarlyView.
ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
T. Zuberbier   +221 more
wiley   +1 more source

Secreted Proteases from Dermatophytes [PDF]

open access: yes, 2018
Dermatophytes are highly specialized pathogenic fungi that exclusively infect the stratum corneum, nails or hair, and it is evident that secreted proteolytic activity is important for their virulence.
Monod, Michel
core  

Cholesterol, a cell size-dependent signal that regulates glucose metabolism and gene expression in adipocytes. [PDF]

open access: yes, 2001
Enlarged fat cells exhibit modified metabolic capacities, which could be involved in the metabolic complications of obesity at the whole body level. We show here that sterol regulatory element-binding protein 2 (SREBP-2) and its target genes are induced ...
C. Farnier   +7 more
core   +2 more sources

Identification and expression characterization of a novel carboxypeptidase A-like gene (RvCPA) during early developmental stages in the gastropod Rapana venosa (Muricidae)

open access: yesAquaculture Reports, 2020
Rapana venosa is an economically important aquaculture species in China. Carboxypeptidases (CPs) A and B (CPA and CPB, respectively) hydrolyze peptides and proteins and play critical roles in the development of the digestive system in animals.
Mei-Jie Yang   +7 more
doaj   +1 more source

The membrane-bound basic carboxypeptidase from hog intestinal mucosa1Enzymes: carboxypeptidase B (EC 3.4.17.2); carboxypeptidase D (EC 3.4.17.-); carboxypeptidase H (EC 3.4.17.10); carboxypeptidase M (EC 3.4.17.12); carboxypeptidase N (EC 3.4.17.3).1

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1999
AbstractThe carboxypeptidase activity occurring in hog intestinal mucosa is apparently due to two distinct enzymes which may be responsible for the release of basic COOH-terminal amino acids from short peptides. The plasma membrane-bound carboxypeptidase activity which occurs at neutral optimum pH levels was found to be enhanced by CoCl2 and inhibited ...
Dalle Ore, Florence   +3 more
openaire   +1 more source

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