Results 21 to 30 of about 5,587 (239)
Molecules, 2021 Microbial biotransformation is an important tool in drug discovery and for metabolism studies. To expand our bioactive natural product library via modification and to identify possible mammalian metabolites, a cytotoxic cardenolide (gitoxigenin) was ...
Erdal Bedir +5 more
doaj +1 more source
Royal Society Open Science, 2022 Predator–prey interactions have long served as models for the investigation of adaptation and fitness in natural environments. Anti-predator defences such as mimicry and camouflage provide some of the best examples of evolution.
Shabnam Mohammadi +3 more
doaj +1 more source
Characterization and Chromatographic Fingerprint Analysis of Traditional Wallflower Oil [PDF]
Research Journal of Pharmacognosy, 2021 Background and objective: Wallflower oil is made from the flowers of Erysimum cheiri (L.) Crantz which is a herb rich in cardenolide compounds. Wallflower oil was traditionally indicated for analgesic, anti-inflammatory, hair tonic, and wound healing ...
Ghazaleh Mosleh +2 more
doaj +1 more source
Quo vadis Cardiac Glycoside Research?
Toxins, 2021 Cardiac glycosides (CGs), toxins well-known for numerous human and cattle poisoning, are natural compounds, the biosynthesis of which occurs in various plants and animals as a self-protective mechanism to prevent grazing and predation.
Jiří Bejček +3 more
doaj +1 more source
LC-MS-based metabolite profiling of aqueous extract of Pergularia tomentosa L. and its anti-hyperglycemic effect [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): In this study, to find scientific evidence for the traditional use of Pergularia tomentosa as an anti-diabetic remedy, the effects of its aqueous extract on streptozotocin-induced diabetes mellitus in rats were evaluated.Materials and ...
Seyed Hamzeh Hosseini +5 more
doaj +1 more source
Progestogens and androgens influence root morphology of angiosperms in a brassinosteroid-independent manner. [PDF]
Plant JSignificance Statement Plants produce progesterone and androgens, which alter root morphology in A. thaliana and 60% of tested angiosperms. Brassinosteroids seem uninvolved. Understanding the mechanism is like navigating an unknown city—exemplarily Dittelbrunn (a small village in Bavaria)—where the expected shortcut (interaction with brassinosteroids ...
Körber KL +11 more
europepmc +2 more sources
Functional Profiles of Phyllosphere and Rhizosphere Metagenomes Differ Across Milkweed Species [PDF]
Environ Microbiol RepWe characterised milkweed microbiomes using a metagenomics approach to investigate the functional potential of endophytic phyllosphere and rhizosphere communities. We found evidence that the composition of potential PSM genes varied across milkweeds in spp. specific responses, for both phyllospheres and rhizospheres, and in response to monarch feeding.
Hansen T, Enders L.
europepmc +2 more sources
Molecular Modes of Action of an Aqueous Nerium oleander Extract in Cancer Cells In Vitro and In Vivo
Molecules, 2023 Cancer drug resistance remains a major obstacle in clinical oncology. As most anticancer drugs are of natural origin, we investigated the anticancer potential of a standardized cold-water leaf extract from Nerium oleander L., termed Breastin.
Luay J. Rashan +9 more
doaj +1 more source
Consequences of toxic secondary compounds in nectar for mutualist bees and antagonist butterflies [PDF]
, 2016 Attraction of mutualists and defense against antagonists are critical challenges for most organisms and can be especially acute for plants with pollinating and non?pollinating flower visitors.
Agrawal, Anurag A., Jones, Patricia L.
core +2 more sources
F1000Research, 2022 Background: Several studies have shown that active compounds of Asclepias subulata (cardenolides) have antiproliferative effect on human cancer cells. Cardenolides isolated from A.
Wagner Vilegas +7 more
doaj +1 more source