Results 11 to 20 of about 14,654 (172)
Anticancer and Antiviral Properties of Cardiac Glycosides: A Review to Explore the Mechanism of Actions [PDF]
Molecules, 2020 Ranjith Kumavath, Debmalya Barh
exaly +2 more sources
Journal of Tropical Pharmacy and Chemistry, 2023 Various medications are being developed using natural products, particularly those resulting from medicinal plants. So, the screening and quantity analysis of phytochemicals in the methanol leaf extract of Erlangea tomentosa was looked at to find out ...
Anselme Mboneye +3 more
doaj +1 more source
Cardiac Glycosides and Cardiomyopathy [PDF]
Hypertension, 2006 Digitalis-like steroids and related agents have been a mainstay in the treatment of congestive heart failure ever since the publication, in 1785, of Withering’s seminal monograph on foxglove. Heart failure refers to the clinical syndrome that results when the heart is unable to pump sufficient blood to keep up with the metabolic demands of the body ...
MANUNTA , PAOLO, FERRANDI M.
openaire +4 more sources
Cardiotoxicity of Plants in Iran: a Review [PDF]
The Iranian Journal of Veterinary Science and Technology, 2018 In this review an attempt has been made to review the cardiotoxic effects of poisonous plants which are found in Iran. Among various plant species growing in different regions of Iran, a large number of plants contain chemical compounds which are ...
Mohammad R. Aslani
doaj +2 more sources
The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction. [PDF]
PLoS ONE, 2017 Cardiac glycosides such as digoxin are Na+/K+-ATPase inhibitors that are widely used for the treatment of chronic heart failure and cardiac arrhythmias; however, recent epidemiological studies have suggested a relationship between digoxin treatment and ...
Motoi Kobayashi +9 more
doaj +1 more source
Live cell screening identifies glycosides as enhancers of cardiomyocyte cell cycle activity
Frontiers in Cardiovascular Medicine, 2022 Promoting cardiomyocyte proliferation is a promising strategy to regenerate the heart. Yet, so far, it is poorly understood how cardiomyocyte proliferation is regulated, and no factor identified to promote mammalian cardiomyocyte proliferation has been ...
Ajit Magadum +11 more
doaj +1 more source
Cardiac glycosides induce cell death in human cells by inhibiting general protein synthesis. [PDF]
PLoS ONE, 2009 BACKGROUND:Cardiac glycosides are Na(+)/K(+)-pump inhibitors widely used to treat heart failure. They are also highly cytotoxic, and studies have suggested specific anti-tumor activity leading to current clinical trials in cancer patients.
Andrea Perne +10 more
doaj +1 more source
Identification of key genes involved in secondary metabolite biosynthesis in Digitalis purpurea
PLoS ONE, 2023 The medicinal plant Digitalis purpurea produces cardiac glycosides that are useful in the pharmaceutical industry. These bioactive compounds are in high demand due to ethnobotany’s application to therapeutic procedures.
Fatemeh Amiri +3 more
doaj +2 more sources
Estimation of Tannin, Saponin, Oxalate, Cyanogenic and Cardiac Glycosides in Garsinia Kola
Journal of Applied Sciences and Environmental Management, 2004 The presence of some secondary plant metabolites — tannin, saponin, oxalate, cyanogenic and cardiac glycosides were done in Garsinia Cola. The tannin, saponin and oxalate content were 0.69 ± 0.01, 15.79 ± 0.28 and 1.707 ± 0.13mg/100g of dry sample ...
C.C. MONAGO, V. AKHIDUE
doaj +1 more source
Cell Communication and Signaling, 2023 Background Acute myeloid leukemia (AML) is an aggressive hematologic malignancy characterized by an accumulation of immature leukemic myeloblasts initiating from leukemic stem cells (LSCs)—the subpopulation that is also considered the root cause of ...
Jirarat Poohadsuan +6 more
doaj +1 more source