Results 11 to 20 of about 17,469 (205)

CARDIAC GLYCOSIDES IN UP-TO-DATE CLINICAL PRACTICE

open access: yesAlʹmanah Kliničeskoj Mediciny, 2016
The article reviews the use of cardiac glycosides in patients with chronic heart failure, paroxysmal tachyarrhythmia and chronic atrial fibrillation (rate control).
M. A. Gurevich, A. A. Gavrilin
doaj   +2 more sources

“Cardiac glycosides”—quo vaditis?—past, present, and future? [PDF]

open access: yesNaunyn-Schmiedeberg's Archives of Pharmacology
Up to date, digitalis glycosides, also known as “cardiac glycosides”, are inhibitors of the Na+/K+-ATPase. They have a long-standing history as drugs used in patients suffering from heart failure and atrial fibrillation despite their well-known narrow ...
Julia Fender   +2 more
exaly   +3 more sources

Estimation of Tannin, Saponin, Oxalate, Cyanogenic and Cardiac Glycosides in Garsinia Kola

open access: yesJournal of Applied Sciences and Environmental Management, 2004
The presence of some secondary plant metabolites — tannin, saponin, oxalate, cyanogenic and cardiac glycosides were done in Garsinia Cola. The tannin, saponin and oxalate content were 0.69 ± 0.01, 15.79 ± 0.28 and 1.707 ± 0.13mg/100g of dry sample ...
C.C. MONAGO, V. AKHIDUE
doaj   +2 more sources

Cardiac glycosides induce cell death in human cells by inhibiting general protein synthesis. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND:Cardiac glycosides are Na(+)/K(+)-pump inhibitors widely used to treat heart failure. They are also highly cytotoxic, and studies have suggested specific anti-tumor activity leading to current clinical trials in cancer patients.
Andrea Perne   +10 more
doaj   +3 more sources

Preliminary Phytochemical Screening and Quantitative Analysis of Methanol Leaf Extract of Erlangea tomentosa (Oliv. & Hiern) S.Moore (Asteraceae)

open access: yesJournal of Tropical Pharmacy and Chemistry, 2023
Various medications are being developed using natural products, particularly those resulting from medicinal plants. So, the screening and quantity analysis of phytochemicals in the methanol leaf extract of Erlangea tomentosa was looked at to find out ...
Anselme Mboneye   +3 more
doaj   +1 more source

Cardiac glycosides are broad-spectrum senolytics. [PDF]

open access: yesNat Metab, 2019
Senescence is a cellular stress response that results in the stable arrest of old, damaged or pre-neoplastic cells. Oncogene-induced senescence is tumour suppressive but can also exacerbate tumorigenesis through the secretion of proinflammatory factors ...
Guerrero A   +25 more
europepmc   +4 more sources

Cardiac Glycosides and Cardiomyopathy [PDF]

open access: yesHypertension, 2006
Digitalis-like steroids and related agents have been a mainstay in the treatment of congestive heart failure ever since the publication, in 1785, of Withering’s seminal monograph on foxglove. Heart failure refers to the clinical syndrome that results when the heart is unable to pump sufficient blood to keep up with the metabolic demands of the body ...
MANUNTA , PAOLO, FERRANDI M.
openaire   +4 more sources

Cardiotoxicity of Plants in Iran: a Review [PDF]

open access: yesThe Iranian Journal of Veterinary Science and Technology, 2018
In this review an attempt has been made to review the cardiotoxic effects of poisonous plants which are found in Iran. Among various plant species growing in different regions of Iran, a large number of plants contain chemical compounds which are ...
Mohammad R. Aslani
doaj   +2 more sources

Cardiac glycosides inhibit cancer through Na/K-ATPase-dependent cell death induction [PDF]

open access: yesBiochemical Pharmacology, 2020
Xinran Geng   +2 more
exaly   +2 more sources

The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction. [PDF]

open access: yesPLoS ONE, 2017
Cardiac glycosides such as digoxin are Na+/K+-ATPase inhibitors that are widely used for the treatment of chronic heart failure and cardiac arrhythmias; however, recent epidemiological studies have suggested a relationship between digoxin treatment and ...
Motoi Kobayashi   +9 more
doaj   +1 more source

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