Phytochemical Screening and in vivo antioxidant activity of Ethanolic extract of caesalpinia bondus (L.) Roxb [PDF]
Phytochemical screening, antioxidant activity in vivo and lipid peroxidation of 75 % ethanolic extract of young twigs and leaves of Caesalpinia bonduc were carried out by chemical test, and assessment of catalase and peroxidase activities and lipid ...
Akindahunsi , A. A +4 more
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Potential Protective Role Exerted by Secoiridoids from Olea europaea L. in Cancer, Cardiovascular, Neurodegenerative, Aging-Related, and Immunoinflammatory Diseases [PDF]
Iridoids, which have beneficial health properties, include a wide group of cyclopentane [c] pyran monoterpenoids present in plants and insects. The cleavage of the cyclopentane ring leads to secoiridoids.
Alarcón de la Lastra Romero, Catalina +3 more
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Cardenolide‐functionalized extracellular vesicles enable targeted delivery of the chemotherapeutic doxorubicin to A549 lung cancer cells by binding Na+/K+‐ATPase, which is overexpressed in these cells. Surface‐modified, drug‐loaded EVs exhibit enhanced cytotoxicity compared to unmodified EVs and free drug, suggesting this system may lower the effective
Maja Dorfner +7 more
wiley +1 more source
Plant Toxins: Poison or Therapeutic?
Many plants that are classed as poisonous also have therapeutic uses, and this is illustrated using members of the Drimia and Digitalis genera which are sources of cardiac glycosides.
Catherine E. Housecroft
doaj +1 more source
Natural cardiac glycosides have positive inotropic heart effects but at high, toxic doses they can cause life-threatening cardiac arrhythmias. Here we present the first Croatian case of a 16-year-old girl who attempted suicide by eating dried oleander ...
Kovačević Tanja +6 more
doaj +1 more source
Preliminary qualitative screening for cancer chemopreventive agents in Telfairia occidentalis Hook.f., Gnetum africanum Welw., Gongronema latifolium Benth. and Ocimum gratissimum L. from Nigeria [PDF]
The leaves of four plant foods commonly consumed in Nigeria namely Gnetum africanum (Igbo name: Ukazi), Gongronema latifolium (Igbo name: Utazi), Telfairia occidentalis (Igbo name: Ugu), Ocimum gratissimum (Igbo name: Nchoanwu), were each screened for ...
Iweala, E. E. J.
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Model of murine ventricular cardiac tissue for in vitro kinematic-dynamic studies of electromagnetic and beta2-adrenergic stimulation [PDF]
In a model of murine ventricular cardiac tissue in vitro, we have studied the inotropic effects of electromagnetic stimulation (frequency, 75 Hz), isoproterenol administration (10 μM), and their combination.
Cornacchione, Marisa +8 more
core +2 more sources
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
Sodium ion channel mutations in glioblastoma patients correlate with shorter survival
Background Glioblastoma Multiforme (GBM) is the most common and invasive astrocytic tumor associated with dismal prognosis. Treatment for GBM patients has advanced, but the median survival remains a meager 15 months.
Velculescu Victor E +3 more
doaj +1 more source
Prolongation of AV nodal refractoriness by Ruta graveolens in isolated rat hearts [PDF]
Objectives: To evaluate concentration-dependent effects of total extract of Rusta graveolens and its purified alkaloid fraction on the nodal basic and functional properties.
Golalipour, M.J. +4 more
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