Results 11 to 20 of about 6,534 (225)

Ionization constants pKa of cardiolipin. [PDF]

PLoS ONE, 2013
Cardiolipin is a phospholipid found in the inner mitochondrial membrane and in bacteria, and it is associated with many physiological functions. Cardiolipin has a dimeric structure consisting of two phosphatidyl residues connected by a glycerol bridge ...
Gerd Olofsson, Emma Sparr
doaj   +4 more sources

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Spatiotemporal AMPKα2 deletion in mice induces cardiac dysfunction, fibrosis and cardiolipin remodeling associated with mitochondrial dysfunction in males only

Biology of Sex Differences, 2021
Highlights AMPK is a metabolic sensor of cellular energy which regulates energy homeostasis. We generated a cardiac-specific inducible deletion of Ampkα2 and demonstrated that this deletion induces mild cardiac dysfunction in male only.
Lucile Grimbert, Maria-Nieves Sanz, Mélanie Gressette, Catherine Rucker-Martin, Marta Novotova, Audrey Solgadi, Ahmed Karoui, Susana Gomez, Kaveen Bedouet, Eric Jacquet, Christophe Lemaire, Vladimir Veksler, Mathias Mericskay, Renée Ventura-Clapier, Jérôme Piquereau, Anne Garnier   +15 more
doaj   +1 more source

Varied Contribution of Phospholipid Shedding From Membrane to Daptomycin Tolerance in Staphylococcus aureus

Frontiers in Molecular Biosciences, 2021
It has been suggested that daptomycin can be inactivated by lipids released by Staphylococcus aureus and that this effect is antagonized by phenol soluble modulins (PSMs), which bind to the shed lipids.
Tianwei Shen, Kelly M. Hines, Nathaniel K. Ashford, Brian J. Werth, Libin Xu   +4 more
doaj   +1 more source

Phospholipid Acyl Chain Diversity Controls the Tissue-Specific Assembly of Mitochondrial Cardiolipins

Cell Reports, 2020
Summary: Cardiolipin (CL) is a phospholipid specific for mitochondrial membranes and crucial for many core tasks of this organelle. Its acyl chain configurations are tissue specific, functionally important, and generated via post-biosynthetic remodeling.
Gregor Oemer, Jakob Koch, Yvonne Wohlfarter, Mohammad T. Alam, Katharina Lackner, Sabrina Sailer, Lukas Neumann, Herbert H. Lindner, Katrin Watschinger, Markus Haltmeier, Ernst R. Werner, Johannes Zschocke, Markus A. Keller   +12 more
doaj   +1 more source

Antioxidant Role and Cardiolipin Remodeling by Redox-Activated Mitochondrial Ca²⁺-Independent Phospholipase A₂γ in the Brain

Antioxidants, 2022
Mitochondrial Ca2+-independent phospholipase A2γ (iPLA2γ/PNPLA8) was previously shown to be directly activated by H2O2 and release free fatty acids (FAs) for FA-dependent H+ transport mediated by the adenine nucleotide translocase (ANT) or uncoupling ...
Pavla Průchová, Klára Gotvaldová, Katarína Smolková, Lukáš Alán, Blanka Holendová, Jan Tauber, Alexander Galkin, Petr Ježek, Martin Jabůrek   +8 more
doaj   +1 more source

Shotgun approach reveals distinctive lipid profiles in brassica oilseeds: A high-resolution ESI-ToF-MS study [PDF]

Emirates Journal of Food and Agriculture
Members of Brassica seed oil are important sources of nutritionally superior edible oil. There are no comprehensive reports on complete lipidomic profile of these oilseed crops.
Sujith Kumar, Ahammed Shabeer, Faraz Rashid, Ibandalin Mawlong, Reema Rani, Vijay Veer Singh, Babli Mog, Manoj Pillai   +7 more
doaj   +3 more sources

New Insights Into the Polar Lipid Composition of Extremely Halo(alkali)philic Euryarchaea From Hypersaline Lakes

Frontiers in Microbiology, 2019
We analyzed the polar membrane lipids of 13 strains of halo(alkali)philic euryarchaea from hypersaline lakes. Nine belong to the class Halobacteria, representing two functional groups: aerobic polysaccharide utilizers and sulfur-respiring anaerobes.
Nicole J. Bale, Dimitry Y. Sorokin, Dimitry Y. Sorokin, Ellen C. Hopmans, Michel Koenen, W. Irene C. Rijpstra, Laura Villanueva, Hans Wienk, Jaap S. Sinninghe Damsté, Jaap S. Sinninghe Damsté   +9 more
doaj   +1 more source

Cardiolipin Interactions with Proteins [PDF]

Biophysical Journal, 2015
Cardiolipins (CL) represent unique phospholipids of bacteria and eukaryotic mitochondria with four acyl chains and two phosphate groups that have been implicated in numerous functions from energy metabolism to apoptosis. Many proteins are known to interact with CL, and several cocrystal structures of protein-CL complexes exist.
Planas-Iglesias, Joan, Dwarakanath, Himal, Mohammadyani, Dariush, Yanamala, Naveena, Kagan, Valerian E., Klein-Seetharaman, Judith   +5 more
openaire   +2 more sources

Purification of cardiolipin for surface pressure studies.

Journal of Lipid Research, 1982
Thin-layer chromatography and surface pressure-area isotherms of commercial bovine cardiolipins showed that the samples contained contaminants. They were purified by TLC and their purity was checked by chromatography and by their monolayer properties ...
A Houle, F Téchy, J Aghion, R M Leblanc
doaj   +1 more source