Results 11 to 20 of about 8,226 (286)

Spatiotemporal AMPKα2 deletion in mice induces cardiac dysfunction, fibrosis and cardiolipin remodeling associated with mitochondrial dysfunction in males only

Biology of Sex Differences, 2021
Highlights AMPK is a metabolic sensor of cellular energy which regulates energy homeostasis. We generated a cardiac-specific inducible deletion of Ampkα2 and demonstrated that this deletion induces mild cardiac dysfunction in male only.
Lucile Grimbert, Maria-Nieves Sanz, Mélanie Gressette, Catherine Rucker-Martin, Marta Novotova, Audrey Solgadi, Ahmed Karoui, Susana Gomez, Kaveen Bedouet, Eric Jacquet, Christophe Lemaire, Vladimir Veksler, Mathias Mericskay, Renée Ventura-Clapier, Jérôme Piquereau, Anne Garnier   +15 more
doaj   +1 more source

Varied Contribution of Phospholipid Shedding From Membrane to Daptomycin Tolerance in Staphylococcus aureus

Frontiers in Molecular Biosciences, 2021
It has been suggested that daptomycin can be inactivated by lipids released by Staphylococcus aureus and that this effect is antagonized by phenol soluble modulins (PSMs), which bind to the shed lipids.
Tianwei Shen, Kelly M. Hines, Nathaniel K. Ashford, Brian J. Werth, Libin Xu   +4 more
doaj   +1 more source

Measuring cardiolipin antibodies [PDF]

BMJ, 1995
EDITOR,—Cardiolipin antibodies have been variously cited as a risk factor for cerebral thrombosis1 2 or splanchnic venous thrombosis,3 or as an epiphenomenon loosely associated with vascular disease.4 Cardiolipin antibodies seem to represent a family of low affinity antibodies which share a limited ability to bind to bovine cardiolipin.
A M, Ward, P A, White
openaire   +2 more sources

Phospholipid Acyl Chain Diversity Controls the Tissue-Specific Assembly of Mitochondrial Cardiolipins

Cell Reports, 2020
Summary: Cardiolipin (CL) is a phospholipid specific for mitochondrial membranes and crucial for many core tasks of this organelle. Its acyl chain configurations are tissue specific, functionally important, and generated via post-biosynthetic remodeling.
Gregor Oemer, Jakob Koch, Yvonne Wohlfarter, Mohammad T. Alam, Katharina Lackner, Sabrina Sailer, Lukas Neumann, Herbert H. Lindner, Katrin Watschinger, Markus Haltmeier, Ernst R. Werner, Johannes Zschocke, Markus A. Keller   +12 more
doaj   +1 more source

Antioxidant Role and Cardiolipin Remodeling by Redox-Activated Mitochondrial Ca²⁺-Independent Phospholipase A₂γ in the Brain

Antioxidants, 2022
Mitochondrial Ca2+-independent phospholipase A2γ (iPLA2γ/PNPLA8) was previously shown to be directly activated by H2O2 and release free fatty acids (FAs) for FA-dependent H+ transport mediated by the adenine nucleotide translocase (ANT) or uncoupling ...
Pavla Průchová, Klára Gotvaldová, Katarína Smolková, Lukáš Alán, Blanka Holendová, Jan Tauber, Alexander Galkin, Petr Ježek, Martin Jabůrek   +8 more
doaj   +1 more source

Haloglomus irregulare gen. nov., sp. nov., a New Halophilic Archaeon Isolated from a Marine Saltern [PDF]

, 2020
A halophilic archaeal strain, designated F16-60T, was isolated from Isla Cristina marine saltern in Huelva, Spain. Cells were pleomorphic, irregular, non-motile, and Gram-stain-negative. It produced red-pigmented colonies on agar plates.
Durán Viseras, Ana, Sánchez-Porro Álvarez, Cristina, Ventosa Ucero, Antonio   +2 more
core   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Shotgun approach reveals distinctive lipid profiles in brassica oilseeds: A high-resolution ESI-ToF-MS study [PDF]

Emirates Journal of Food and Agriculture
Members of Brassica seed oil are important sources of nutritionally superior edible oil. There are no comprehensive reports on complete lipidomic profile of these oilseed crops.
Sujith Kumar, Ahammed Shabeer, Faraz Rashid, Ibandalin Mawlong, Reema Rani, Vijay Veer Singh, Babli Mog, Manoj Pillai   +7 more
doaj   +3 more sources

New Insights Into the Polar Lipid Composition of Extremely Halo(alkali)philic Euryarchaea From Hypersaline Lakes

Frontiers in Microbiology, 2019
We analyzed the polar membrane lipids of 13 strains of halo(alkali)philic euryarchaea from hypersaline lakes. Nine belong to the class Halobacteria, representing two functional groups: aerobic polysaccharide utilizers and sulfur-respiring anaerobes.
Nicole J. Bale, Dimitry Y. Sorokin, Dimitry Y. Sorokin, Ellen C. Hopmans, Michel Koenen, W. Irene C. Rijpstra, Laura Villanueva, Hans Wienk, Jaap S. Sinninghe Damsté, Jaap S. Sinninghe Damsté   +9 more
doaj   +1 more source

Molecular Basis and Consequences of the Cytochrome c-tRNA Interaction. [PDF]

, 2016
The intrinsic apoptosis pathway occurs through the release of mitochondrial cytochrome c to the cytosol, where it promotes activation of the caspase family of proteases.
Christian, Thomas, Hou, Ya-Ming, Liu, Cuiping, Stonestrom, Aaron J, Takase, Ryuichi, Yang, Xiaolu, Yong, Jeongsik   +6 more
core   +2 more sources