Polyunsaturated fatty acids (PUFA) are particularly susceptible to free radical-induced lipid peroxidation (LPO). Specific deuteration at bis-allylic positions of PUFA (D-PUFA) has been recently proposed as a way to inhibit the LPO.
Rosangela S. Santos +7 more
doaj +1 more source
Rare presentation of an atrial myxoma in an adolescent patient: A case report and literature review [PDF]
BACKGROUND: Cardiac tumors are uncommon in the pediatric population. When present, cardiac manifestations stem from the tumor causing inflow or outflow obstruction.
Anwar, Shafkat +6 more
core +3 more sources
Purification of cardiolipin for surface pressure studies.
Thin-layer chromatography and surface pressure-area isotherms of commercial bovine cardiolipins showed that the samples contained contaminants. They were purified by TLC and their purity was checked by chromatography and by their monolayer properties ...
A Houle, F Téchy, J Aghion, R M Leblanc
doaj +1 more source
Immunological study on cardiolipin from Escherichia coli [PDF]
For the first time we found that cardiolipin was contained abundantly in Eschrichia coli, and we succeeded in isolating and purifying it as reported previously. With this E.
Kanemasa, Yasuhiro
core +1 more source
Mitochondrial ADP/ATP Carrier in Dodecylphosphocholine Binds Cardiolipins with Non-native Affinity. [PDF]
Biophysical investigation of membrane proteins generally requires their extraction from native sources using detergents, a step that can lead, possibly irreversibly, to protein denaturation.
Chipot, Christophe +4 more
core +4 more sources
Sphingolipids in human synovial fluid : a lipidomic study [PDF]
Articular synovial fluid (SF) is a complex mixture of components that regulate nutrition, communication, shock absorption, and lubrication. Alterations in its composition can be pathogenic. This lipidomic investigation aims to quantify the composition of
Kaesser, Ulrich +10 more
core +8 more sources
Determination of cellular lipids bound to human CD1d molecules. [PDF]
CD1 molecules are glycoproteins that present lipid antigens at the cell surface for immunological recognition by specialized populations of T lymphocytes.
Daryl Cox +7 more
doaj +1 more source
Elamipretide Improves Mitochondrial Function in Mitochondrial Trifunctional Protein-Deficient Mice and Human Fibroblasts. [PDF]
ABSTRACT Mitochondrial trifunctional protein (TFP) deficiency is an inherited disorder of long‐chain fatty acid β‐oxidation (FAO). TFP is a heteromeric enzyme composed of two α and two β‐subunits. Despite early detection and dietary treatment, TFP deficiency patients often develop hypoglycemia, rhabdomyolysis, cardiomyopathy, and peripheral neuropathy.
Vieira Neto E +8 more
europepmc +2 more sources
LPS remodeling triggers formation of outer membrane vesicles in Salmonella. [PDF]
Outer membrane vesicles (OMV) are proposed to mediate multiple functions during pathogenesis and symbiosis. However, the mechanisms responsible for OMV formation remain poorly understood.
Bording-Jorgenson, Michael +5 more
core +3 more sources
Role of mitochondria and cardiolipins in growth inhibition of breast cancer cells by retinoic acid
Background All-trans-retinoic-acid (ATRA) is a promising agent in the prevention/treatment of breast-cancer. There is growing evidence that reprogramming of cellular lipid metabolism contributes to malignant transformation and progression.
Mineko Terao +15 more
doaj +1 more source

