Results 21 to 30 of about 6,534 (225)

Determination of cellular lipids bound to human CD1d molecules. [PDF]

open access: yesPLoS ONE, 2009
CD1 molecules are glycoproteins that present lipid antigens at the cell surface for immunological recognition by specialized populations of T lymphocytes.
Daryl Cox   +7 more
doaj   +1 more source

Role of mitochondria and cardiolipins in growth inhibition of breast cancer cells by retinoic acid

open access: yesJournal of Experimental & Clinical Cancer Research, 2019
Background All-trans-retinoic-acid (ATRA) is a promising agent in the prevention/treatment of breast-cancer. There is growing evidence that reprogramming of cellular lipid metabolism contributes to malignant transformation and progression.
Mineko Terao   +15 more
doaj   +1 more source

Native-like membrane models of E. coli polar lipid extract shed light on the importance of lipid composition complexity

open access: yesBMC Biology, 2021
Background Lipid-protein interactions stabilize protein oligomers, shape their structure, and modulate their function. Whereas in vitro experiments already account for the functional importance of lipids by using natural lipid extracts, in silico methods
Kristyna Pluhackova, Andreas Horner
doaj   +1 more source

Structure of Cardiolipin [PDF]

open access: yesNature, 1958
PANGBORN1 considered that the glycerylglycero-phosphate skeleton of cardiolipin contained three phosphoric acid and four glycerol residues (I), the six available hydroxyl groups in this structure being esterified with unsaturated fatty acids in the intact phospholipid.
openaire   +2 more sources

A Five-Year Update on Matrix Compounds for MALDI-MS Analysis of Lipids

open access: yesBiomolecules, 2023
Matrix-assisted laser desorption and ionization (MALDI) is a widely used soft-ionization technique of modern mass spectrometry (MS). MALDI enables the analysis of nearly all chemical compounds—including polar and apolar (phospho)lipids—with a minimum ...
Jenny Leopold   +3 more
doaj   +1 more source

2357 Lost and found: Detection of brain cardiolipins in plasma after cardiac arrest

open access: yesJournal of Clinical and Translational Science, 2018
OBJECTIVES/SPECIFIC AIMS: Neurological injury remains as the main limiting factor for overall recovery after cardiac arrest (CA). Currently available indicators of neurological injury are inadequate for early prognostication after return of spontaneous ...
Andrew M. Lamade   +9 more
doaj   +1 more source

Oxidative Stress Linked Organ Lipid Hydroperoxidation and Dysregulation in Mouse Model of Nonalcoholic Steatohepatitis: Revealed by Lipidomic Profiling of Liver and Kidney

open access: yesAntioxidants, 2021
Nonalcoholic steatohepatitis (NASH) is a prevalent disease related to lipid metabolism disorder and oxidative stress. Lipid hydroperoxidation is known to be a critical driving force of various disorders and diseases.
Yue Wu   +8 more
doaj   +1 more source

Clarifying the Roles of Cardiolipin [PDF]

open access: yesBiophysical Journal, 2014
Cardiolipins (CL) are uniquely structured double lipids that are universally found in membranes which couple electron transport and phosphorylation. The proposed roles of CL in these membranes include mainly two aspects: the effects on the structure and dynamics of the membranes' lipid component and the interplay with membrane-associated proteins.
Pöyry, Sanja   +7 more
openaire   +1 more source

Dietary macronutrients modulate the fatty acyl composition of rat liver mitochondrial cardiolipins[S]

open access: yesJournal of Lipid Research, 2013
The interaction of dietary fats and carbohydrates on liver mitochondria were examined in male FBNF1 rats fed 20 different low-fat isocaloric diets.
Irina G. Stavrovskaya   +7 more
doaj   +1 more source

Osmotic shock stimulates de novo synthesis of two cardiolipins in an extreme halophilic archaeon

open access: yesJournal of Lipid Research, 2004
The present report illustrates the response to osmotic stress of an extreme halophilic archaeon, Halorubrum sp., isolated from the saltern ponds of Margherita di Savoia in southern Italy.
Patrizia Lopalco   +3 more
doaj   +1 more source

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