Results 91 to 100 of about 34,988 (231)
, 2014 Nonstructural protein 5A (NS5A) of hepatitis C virus (HCV) possesses multiple functions in the viral life cycle. NS5A is a phosphoprotein that exists in hyperphosphorylated and basally phosphorylated forms.
Lemon, S. M. +14 more
core +2 more sources
Stimulation of Suicidal Erythrocyte Death by Phosphatase Inhibitor Calyculin A
Cellular Physiology and Biochemistry, 2016 Background/Aims: The serine/threonine protein phosphatase 1 and 2a inhibitor Calyculin A may trigger suicidal death or apoptosis of tumor cells. Similar to apoptosis of nucleated cells, erythrocytes may enter eryptosis, the suicidal erythrocyte death ...
Mustafa Almasry +4 more
doaj +1 more source
Insights Into the Role of Lysine Acetylation of Non‐Histone Proteins in Plant Immunity
Plant, Cell &Environment, EarlyView.ABSTRACT Plant immunity is regulated by numerous transcriptional and posttranslational mechanisms. Among these, lysine acetylation, which is controlled by lysine acetyltransferases (KATs) and lysine deacetylases (KDACs), has been extensively studied, particularly in the context of epigenetic regulation through histone acetylation.
Jérémy Villette +5 more
wiley +1 more source
Phosphorylation of Elp1 by Hrr25 is required for elongator-dependent tRNA modification in yeast.
PLoS Genetics, 2015 Elongator is a conserved protein complex comprising six different polypeptides that has been ascribed a wide range of functions, but which is now known to be required for modification of uridine residues in the wobble position of a subset of tRNAs in ...
Wael Abdel-Fattah +9 more
doaj +1 more source
Unlocking the therapeutic potential of protein kinase inhibitors in neurodegenerative and psychiatric disorders [PDF]
Exploration of Drug ScienceProtein phosphorylation is a fundamental regulatory mechanism governing a broad spectrum of cellular processes. In the nervous system, it is critical for modulating neurotransmitter release, synaptic plasticity, neuronal excitability, and cell survival ...
Angela Asir R V +2 more
doaj +1 more source
14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses
The Journal of Physiology, EarlyView.Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley +1 more source
The use of edible insects in human food
Journal of the Science of Food and Agriculture, Volume 106, Issue 10, Page 5775-5787, 15 August 2026.Abstract The world population is expected to reach approximately 10 billion people by 2050, which will significantly increase global food demand and may lead to agricultural shortages and a higher risk of food insecurity. In this context, this review discusses the potential of insects as alternative sources of animal protein, addressing their ...
Pamela Barroso de Oliveira +5 more
wiley +1 more source
Study of the Role of Casein Kinase I epsilon in Breast Cancer Using Drosophila as a Model
, 2009 A particular allele of the Drosophila discs overgrown locus called dco3 leads to hyperplastic overgrowth of imaginal wing discs. Since high rate of mutations in human homologue of the dco gene coding Casein kinase I epsilon was found in breast cancer ...
MATULOVÁ, Jana
core
PLoS ONE, 2016 Phosphorylation at serine 235 (S235) of the hepatitis C virus (HCV) non-structural protein 5A (NS5A) plays a critical role in the viral life cycle. For medical and virological interests, we exploited the HEK293T kidney cells to test 3 candidate protein ...
Kuan-Ying Lee +3 more
doaj +1 more source