Results 71 to 80 of about 147,909 (161)

Dual Cytoplasmic and Chloroplastic Mechanisms Fine‐Tune Chloroplast Division through ARC3 Protein Stability

Advanced Science, Volume 13, Issue 45, 13 August 2026.
ARC3 levels are controlled by cytosolic and chloroplast proteolytic systems. PUB52 mediates ARC3 precursor ubiquitination and degradation in the cytosol, while CLPC1 promotes ARC3 degradation in chloroplasts, where ARC2 protects ARC3 from excessive breakdown. Disrupting these components causes chloroplast division defects, placing them upstream of ARC3.
Yang Yuan, Denghao Xiang, Ruiying Li, Zhichuang Yue, Zhipeng Wang, Honghong Hu   +5 more
wiley   +1 more source

Synthetic Gene-Based Heterologous Expression, Proteolytic, and Structural Characterization of Caseinolytic Protease of Lactobacillus plantarum IIA-1A5

Tropical Animal Science Journal, 2021
Genome sequence of Indonesian probiotic of Lactobacillus plantarum II1A5 contains a gene encoding a proteolytic subunit of caseinolytic protease, designated as ClpP_LP.
M. Yusuf, C. Budiman, I. I. Arief, C. Sumantri   +3 more
doaj   +1 more source

Protease Inhibitors and their Relation to Protease Activity in Human Milk

, 1982
Protease inhibitors and protease (caseinolytic, elastinolytic and esterolytic) activity were analysed in 190 milk samples from 94 mothers from day 1 to day 160 after delivery The main protease inhibitors in human milk are α1-antichymotrypsin and α1 ...
Kjell Ohlsson, Tor Lindberg, Ohlsson, Kjell, Weström, Björn, Björn Weström, Lindberg, Tor, Lindberg, Tor,, Ohlsson, Kjell,, Weström, Björn,   +8 more
core   +1 more source

Role of ClpX and MsrA/B in the Oxidative and Cell Wall Stress Response in Bacillus anthracis Sterne

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Methionine sulfoxide reductase (msrA/B) is an oxidative response enzyme that reduces oxidized methionine residues to maintain protein function. Surprisingly, loss of MsrA/B does not increase sensitivity to hydrogen peroxide or paraquat‐induced oxidative stress in Bacillus anthracis Sterne.
Aeron B. Pennington, Salina Hona, Josey I. Austin, Kelsey C. Waite, Mikaela D. Stewart, Shauna M. McGillivray   +5 more
wiley   +1 more source

Synthesis of Caseinolytic Protease Agonists Towards the Synthesis of the Natural Acyldepsipeptides [PDF]

, 2011
Caseinolytic protease (ClpP) is a cylindrical protease forming the core of protein degradation machinery in eubacteria. ClpP is tightly regulated and is non-functional without a member of the Clp-ATPases. A new class of antibiotics, termed ADEPs, bind to
Cossette, Michele
core  

Effects of protease inhibitors on V1 activity.

, 2013
(A) Normal cycling and ovariectomized vagina extracts shown in Figure 2 were subjected to protease inhibition. EDTA (10 mM) or PMSF (100 µM) was incubated with each extract before casein zymography.
Ruth Ann Word (380217), Madhusudhan Budatha (380211), Simone Silva (380212), Masashi Yanagisawa (224823), Teodoro Ignacio Montoya (380213), Ayako Suzuki (380214), Cecilia Karin Wieslander (380216), Hiromi Yanagisawa (380218), Sheena Shah-Simpson (380215)   +8 more
core   +1 more source

Protein Homeostasis and Mitochondrial Quality Control in Neurodegeneration

WIREs Mechanisms of Disease, Volume 18, Issue 4, July/August 2026.
Quality control pathways form an integrated proteostasis–mitochondrial quality control axis that maintains mitochondrial and cellular homeostasis. Failure of this coordinated network drives neuronal decline and contributes to neurodegeneration. ABSTRACT Quality control (QC) processes include a network of cellular pathways that prevent the accumulation ...
Rosa Di Lorenzo, Rola S. Zeidan, Riccardo Calvani, Vito Pesce, Emanuele Marzetti, Anna Picca   +5 more
wiley   +1 more source

Mitochondrial Dysfunction at the Crossroads of Necroptosis: Mechanisms, Molecular Mediators, and Therapeutic Opportunities

Journal of Cellular and Molecular Medicine, Volume 30, Issue 14, July 2026.
ABSTRACT The conceptual landscape of cell death has evolved beyond the traditional dichotomy of apoptosis and necrosis to encompass diverse regulated pathways including necroptosis, autophagy, ferroptosis, and pyroptosis. Necroptosis, a caspase‐independent inflammatory form of programmed cell death, has emerged as a critical driver of the pathogenesis ...
Fengxin Wang, Haiying Rui, Dandan Qin, Huaxiang Yu, Dan Zou, Wenyi Zou, Yuting Li, Ran Li, Yuguo Chen, Li Xue   +9 more
wiley   +1 more source

Targeted proteomics reveal α-MSH-like Enterobacterial ClpB protein in gut microbiota of patients with anorexia nervosa

npj Biofilms and Microbiomes
α-melanocyte-stimulating hormone (α-MSH) is an anorexigenic peptide. In this exploratory study, a targeted proteomic approach was used to detect α-MSH-like bacterial proteins in the gut microbiota of patients with anorexia nervosa (AN) and healthy ...
Lisa Bremard, Lisa Wallart, Emilie Lahaye, Mohamed Amine Ben Mlouka, Jochen Seitz, Beate Herpertz-Dahlmann, Sergueï O. Fetissov   +6 more
doaj   +1 more source

An extracellular - Pepstatin insensitive acid protease produced by Thermoplasma volcanium

, 2007
In this study, some parameters for the production and caseinolytic activity of an extracellular thermostable acid protease from a thermoacidophilic archaeon Thermoplasma volcanium were determined.
Kocabıyık, Semra, Ozel, Hatice, Kocabiyik, Semra   +2 more
core   +1 more source