Results 221 to 230 of about 526,882 (310)

Decision letter: CasExpress reveals widespread and diverse patterns of cell survival of caspase-3 activation during development in vivo

, 2015

openalex   +1 more source

Activation of TRPV4 to drive pyroptosis-dependent orthodontic tooth remodeling. [PDF]

Sci Prog
He Z, Tian H, Liu X, Duan Y, Chen M, Luo Z.   +5 more
europepmc   +1 more source

Mechanisms of caspase activation and inhibition during apoptosis.

Molecules and Cells, 2002
Yigong Shi
semanticscholar   +1 more source

Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition

Advanced Science, EarlyView.
Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han, June‐Hyun Jeong, Dongjoon Lee, Yujin Jung, Yujin Jin, Eun Sun Jung, Haeng Jun Kim, Woo Youn Kim, Chang‐Han Lee, Inhee Mook‐Jung   +9 more
wiley   +1 more source

METTL14 Overexpression Promotes Osteosarcoma Cell Apoptosis and Slows Tumor Progression via Caspase 3 Activation

, 2020
Liu Z, Liu N, Zhijie Huang, Wei Wang
openalex   +1 more source

Targeting glial cell pyroptosis and neuroinflammation in post-stroke depression: from molecular mechanisms to therapeutic strategies. [PDF]

Front Immunol
Li X, Wei Y, She Y, Long W, Zhou S, Shi M, Wang Z, Zou X, Mao J, Xiao X, Shi H, Qin D.   +11 more
europepmc   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

Hypericin alleviates cerebral ischemia/reperfusion injury by modulating endoplasmic reticulum stress. [PDF]

Front Pharmacol
Li T, Wang C.
europepmc   +1 more source

An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells

Science, 2016
I. Zanoni, Yunhao Tan, M. di Gioia, A. Broggi, J. Ruan, Jianjin Shi, C. Donado, F. Shao, Hao Wu, James R. Springstead, Jonathan C. Kagan   +10 more
semanticscholar   +1 more source

Early Detection of Cell Death Using Transmembrane Water Exchange Magnetic Resonance Imaging

Advanced Science, EarlyView.
Cell death is important in both the development and treatment of cancer. In this study, it is demonstrated for the first time that a specific measurement of the transmembrane water exchange rate using magnetic resonance imaging can be used as an early marker of cell death in mammalian cells, in animals and in human patients. Abstract Cell death plays a
Athanasia Kaika, Luca Nagel, Ulrike Höckendorf, Bangwen Xie, Geoffrey J. Topping, Mathias Schillmaier, Irina Beer, Frits H. A. van Heijster, Julian Rauch, Tristan A. Kuder, Sandra Sühnel, Bernd Erber, Christian Lohrmann, Simone Ballke, Thomas Metzler, Katja Steiger, Philipp J. Jost, Natalia P. Ivleva, Philipp Paprottka, Jonathan Nadjiri, Kevin M. Brindle, Wolfgang A. Weber, Franz Schilling   +22 more
wiley   +1 more source