Results 221 to 230 of about 514,126 (359)

Depletion of Caspase-12 Alleviates Retinal Degeneration in Aged BALB/c Mice Following Systemic Neonatal Infection by Murine Cytomegalovirus (MCMV). [PDF]

Viruses
Xu J, Zhang X, Liao Y, Shi T, Marshall B, Zhang M.   +5 more
europepmc   +1 more source

Ceramide accumulation precedes caspase-dependent apoptosis in CHP-100 neuroepithelioma cells exposed to the protein phosphatase inhibitor okadaic acid [PDF]

, 1999
Angelo Spinedi, Sabrina Di Bartolomeo, Federica Di Sano, Carlo Rodolfo, A Ambrosino, Mauro Piacentini   +5 more
openalex   +1 more source

Deficiency of SCAMP5 Triggers Pancreatic β‐Cell Secretory Dysfunction and Apoptosis

Advanced Science, EarlyView.
This study demonstrates that hyperglycemia in diabetes activates ChREBP, which epigenetically represses SCAMP5 expression in pancreatic β‐cells. This SCAMP5 deficiency impairs insulin secretion by downregulating the calcium channel CaV1.2. Furthermore, reduced SCAMP5 triggers β‐cell apoptosis by stabilizing VDAC1 and enhancing its interaction with Bax,
Yingqi Zhang, Donglan Tang, Chenxi Yang, Chao Lin, Yingyue Yuan, Meiying He, Yiying Chen, Zhuo Mao, Ying Ying, Xiaosong Ma, Xiangchen Kong   +10 more
wiley   +1 more source

Qushi huayu decoction dose-dependent inhibition of caspase-2/SREBP-1 in MASLD mice. [PDF]

Hereditas
Liu Q, Gu Z, Xin X, Shen X, Gou X, Hou L, Li S.   +6 more
europepmc   +1 more source

An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells

Science, 2016
I. Zanoni, Yunhao Tan, M. di Gioia, A. Broggi, J. Ruan, Jianjin Shi, C. Donado, F. Shao, Hao Wu, James R. Springstead, Jonathan C. Kagan   +10 more
semanticscholar   +1 more source

Deacetylation of ACLY Mediates RNA M6A‐Modification of NOXA and Promotes Chemoresistance of Colorectal Cancer

Advanced Science, EarlyView.
This study investigates the deacetylation of ACLY at K978 acts as a novel risk in colorectal cancer chemoresistance. The deacetylation of K978 induces ACLY relocation to the nucleus and promotes its binding to RBM15, a m6A methylation modification “writer”.
Jun Wen, Mengqin Shen, Haitao Zhao, Liu Liu, Qian Hua, Xiaoping Zhao, Jianjun Liu, Haizhong Feng, Gang Huang   +8 more
wiley   +1 more source

Crosstalk Between Cell Death and the cGAS-STING Pathway in Sepsis-Associated Acute Lung Injury. [PDF]

J Inflamm Res
Li X, Wang M, Li Y, Huang Y, Zhang X.
europepmc   +1 more source

Prodomain-dependent Nuclear Localization of the Caspase-2 (Nedd2) Precursor

, 1998
Paul A. Colussi, Natasha L. Harvey, Sharad Kumar   +2 more
openalex   +1 more source

Suicidal Tendencies: Apoptotic Cell Death by Caspase Family Proteinases [PDF]

, 1999
Beni B. Wolf, Douglas R. Green
openalex   +1 more source

HIFU‐Driven Targeted Pyroptosis Therapy in Basal‐Like Breast Cancer

Advanced Science, EarlyView.
This study presents a HIFU‐driven pyroptosis strategy for BLBC treatment. Combining HIFU with platelet‐membrane hybridized liposomes encapsulating mitoxantrone enhances tumor targeting and efficacy. The synergistic treatment modulates key epigenetic regulators and activates the pyroptotic pathway through ROS generation and inflammasome signaling ...
Xiaomin Su, Yang Wang, Xifeng Qin, Yaqiong Xiao, Boshu Ouyang, Lina Hu, Lin Kang, Ruizhe Xu, Ce Xu, Zanya Sun, Chenyu Sun, Huishu Guo, Zhiqing Pang, Shun Shen   +13 more
wiley   +1 more source