Results 1 to 10 of about 530,883 (357)

Apoptosis in prostate carcinoma tissue: The role of caspase-3, caspase-1, and alkaline DNase activity [PDF]

Journal of Medical Biochemistry
Background: Prostate glandular tissue maintains a delicate balance between cellular proliferation and programmed cell death (apoptosis), ensuring the preservation of normal glandular architecture in healthy individuals.
Veljkovic Andrej, Hadzi-Djokic Jovan, Kocic Gordana, Li Xiaobo, Roumeliotis Stefanos, Sokolović Dušan, Klisic Aleksandra   +6 more
doaj   +2 more sources

Evaluation of the Potential Diagnostic Utility of the Determination of Selected Caspases—Markers Involved in the Regulation of Apoptosis—In Patients with Ovarian Cancer

Diagnostics, 2021
Ovarian cancer remains a major diagnostic and therapeutic problem in modern gynecological oncology. For this reason, research which focuses on the search for new diagnostic markers and the assessment of their possible usefulness in clinical practice is ...
Aleksandra Mielczarek-Palacz, Sylwia Jasińska, Anna Strzelec   +2 more
doaj   +1 more source

Roles of apoptosis and autophagy in natural rabies infections

Veterinární Medicína, 2022
The aim of this study was to investigate the activity of apoptosis and autophagy in animals (cows, horses, donkeys, dogs and cats) naturally infected with rabies by using immunohistochemistry, immunofluorescence, and qPCR.
M Ozkaraca, S Ozdemir, S Comakli, Timurkan MO   +3 more
doaj   +1 more source

The calpain, caspase 12, caspase 3 cascade leading to apoptosis is altered in F508del-CFTR expressing cells. [PDF]

PLoS ONE, 2009
In cystic fibrosis (CF), the most frequent mutant variant of the cystic fibrosis transmembrane conductance regulator (CFTR), F508del-CFTR protein, is misfolded and retained in the endoplasmic reticulum (ER). We previously showed that the unfolded protein
Mathieu Kerbiriou, Ling Teng, Nathalie Benz, Pascal Trouvé, Claude Férec   +4 more
doaj   +1 more source

Analyses of the differential expression of cloned Caspase-3 and Caspae-9 genes, of Onchidium reevesii, exposed to extreme hot and cold conditions

Aquaculture and Fisheries, 2021
During low tide intertidal organisms face severe temperature fluctuations. This situation may be more pronounced in the context of climate change.
Fengshen Zhao, Heding Shen
doaj   +1 more source

Effects of Scrophularia oxysepala Methanolic Extract on Early Stagesof Dimethylhydrazine-Induced Colon Carcinoma in Rats: ApoptosisPathway Approach [PDF]

Advanced Pharmaceutical Bulletin, 2022
Purpose: Colorectal cancer is one of the most prevalent cancers, worldwide. The presentstudy aimed to examine the effects of Scrophularia oxysepala (SO) methanolic extract on1,2-dimethylhydrazine (DMH) induced colon cancer model in the Wistar rats ...
Ali Namvaran, Mehdi Fazeli, Safar Farajnia, Gholamreza Hamidian, Hassan Rezazadeh   +4 more
doaj   +1 more source

Astaxanthin effect on apoptotic biomarkers in methotrexate-induced liver injury

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2022
Methotrexate is used in the treatment of cancer, psoriasis, rheumatoid arthritis and several other disorders. It has a hepatotoxic potential side effect. Patients who have no access to alternative medications face a serious   challenge as a result.
Sarah Saad Hamdan, Yassir Mustafa Kamal, Huda Jaber Waheed   +2 more
doaj   +1 more source

MDA-MB-231 cell apoptosis in vitro induced by dihydromyricetin

浙江大学学报. 农业与生命科学版, 2012
To investigate the effect of dihydromyricetin (DMY) induction on MDA-MB-231 cell apoptosis and its mechanism, the changes of cell morphological characteristics were observed under inverted microscope.
ZHOU Fang-zhen, ZHANG Xiao-yuan, SUN Fen-yong, GUO Yong   +3 more
doaj   +1 more source

Altered of apoptotic markers of both extrinsic and intrinsic pathways induced by hepatitis C virus infection in peripheral blood mononuclear cells

Virology Journal, 2012
Background Chronic hepatitis C (CHC) has emerged as a leading cause of cirrhosis in the U.S. and across the world. To understand the role of apoptotic pathways in hepatitis C virus (HCV) infection, we studied the mRNA and protein expression patterns of ...
Albertoni Guilherme, Arnoni Carine Prisco, Latini Flávia Roche Moreira, Andrade Sheila Siqueira, Araújo Patrícia Regina Barboza, Rodrigues Flaviane Kesia, Rozenchan Patrícia Bortman, Mendes-Correa Maria Cássia, Leite Olavo Henrique Munhoz, Schor Nestor, Girão Manoel João Castelo Batista, Barreto José   +11 more
doaj   +1 more source

The therapeutic effect of conditioned medium of human amniotic membrane stem cells on heart failure in rats [PDF]

مجله پزشکی دانشگاه علوم پزشکی تبریز, 2023
Background. The conditioned medium of stem cells plays an important role in the treatment of various diseases such as heart damage, but its molecular mechanisms are unknown.
Nahid Aboutaleb, Mahdieh Mehrab Mohseni, Mohammad Reza Khalilzadeh, Neda Mousavi Niri, Maryam Naseroleslami   +4 more
doaj   +1 more source