Results 61 to 70 of about 90,413 (210)

Ruellia tuberosa Ethyl Acetate Leaf Extract Induces Apoptosis and Cell Cycle Arrest in Human Breast Cancer Cell Line, MCF-7

Scientia Pharmaceutica, 2022
Ruellia tuberosa L. has been previously shown to possess antioxidant and antiproliferative activities on cancer cells but its underlying mechanisms are largely unknown. This study aimed to elucidate the mode of action underlying this inhibitory effect on
Fui Fui Lem, Bo Eng Cheong, Peik Lin Teoh   +2 more
doaj   +1 more source

H2O2 INDUCES APOPTOSIS OF RABBIT CHONDROCYTES VIA BOTH THE EXTRINSIC AND THE CASPASE-INDEPENDENT INTRINSIC PATHWAYS [PDF]

Journal of Innovative Optical Health Sciences, 2013
Osteoarthritis (OA), one of the most common joint diseases with unknown etiology, is characterized by the progressive destruction of articular cartilage and the apoptosis of chondrocytes. The purpose of this study is to elucidate the molecular mechanisms
CAIPING ZHUANG, XIAOPING WANG, TONGSHENG CHEN   +2 more
doaj   +1 more source

Potential of Therapeutic Small Molecules in Apoptosis Regulation in the Treatment of Neurodegenerative Diseases: An Updated Review

Molecules, 2022
Neurodegenerative disorders (NDs) include Parkinson’s disease (PD), Alzheimer’s disease (AD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS) and the common feature of NDs is the progressive death of specific neurons in the brain ...
Hamad Ghaleb Dailah
doaj   +1 more source

Rapid and significant induction of TRAIL-mediated type II cells in apoptosis of primary salivary epithelial cells in primary Sjögren's syndrome. [PDF]

, 2008
Expressions of the effector molecules of Fas-mediated apoptosis in primary cultured salivary gland epithelial cells (SGEC) of primary Sjögren's syndrome (pSS) remain to be clarified.
Eguchi, Katsumi, Nakamura, Hideki, Ida, Hiroaki, Kawakami, Atsushi, Koji, Takehiko, Iwamoto, Naoki   +5 more
core   +1 more source

Regulated Cell Death in Fungi, the Role of Metacaspases and Assay Techniques

Methods and Protocols
Caspases orchestrate metazoan apoptosis, regulating processes such as embryogenesis, the death of old and infected cells and immune tolerance. Structural orthologs of caspases have been identified in bacteria, plants, protists and fungi and regulated ...
Derek Wilkinson
doaj   +1 more source

PF2401-SF, Standardized Fraction of Salvia miltiorrhiza, Induces Apoptosis of Activated Hepatic Stellate Cells in Vitro and in Vivo

Molecules, 2013
During the course of our attempts to develop a potential herbal medicine, we had previously prepared PF2401-SF, a standardized fraction of S. miltiorrhiza, and reported its hepatoprotective activity in vitro as well as in vivo.
Dong Hwan Sohn, Youn-Chul Kim, Wen-Yi Jiang, Xian-Hua Che, Eun-Jeon Park, Daya Ram Parajuli, Sung Hee Lee   +6 more
doaj   +1 more source

Pro-Apoptotic Activity of Bioactive Compounds from Seaweeds: Promising Sources for Developing Novel Anticancer Drugs

Marine Drugs, 2023
The process by which cancer cells evade or inhibit apoptosis is considered one of the characteristics of cancer. The ability of cancer cells to escape apoptosis contributes to tumor proliferation and promotes metastasis.
Rosette Agena, Alejandro de Jesús Cortés-Sánchez, Humberto Hernández-Sánchez, María Eugenia Jaramillo-Flores   +3 more
doaj   +1 more source

TUDCA's effect on various caspases after RD. [PDF]

, 2013
Assay of Caspases 2, 3, 8, and 9 activity after RD and TUDCA treatment. Treatment of RD with TUDCA decreased the activation of caspases 2, 3 and 9 (n = 6, p0.05).
Joan W. Miller (153682), Jason Comander (343473), Demetrios G. Vavvas (153676), Yusuke Murakami (104934), Miin Roh (153662), Dimosthenis Mantopoulos (343471), Aristomenis Thanos (153668)   +6 more
core   +1 more source

A Comparative Review of Pyroptosis in Mammals and Fish

Journal of Inflammation Research, 2022
Zixi Song,* Jiahong Zou,* Mengya Wang, Zhenwei Chen, Qingchao Wang Engineering Research Center of Green Development for Conventional Aquatic Biological Industry in the Yangtze River Economic Belt, Ministry of Education, College of Fisheries ...
Song Z, Zou J, Wang M, Chen Z, Wang Q
doaj  

Apoptosis Inducing Factors Involved in the Changes of Flesh Quality in Postmortem Grass Carp (Ctenopharyngodon idella) Muscle

Foods, 2022
Alterations of apoptosis have notable influences on flesh quality, but the mechanism is still unclear. Thus, apoptotic behaviors and related triggering mechanisms need to be explored. Fish muscle was prepared and stored at 4 °C for 0, 24, 48, 72, 96, and
Huaimao Tie, Xuan Lu, Dawei Yu, Fang Yang, Qixing Jiang, Yanshun Xu, Wenshui Xia   +6 more
doaj   +1 more source