Results 101 to 110 of about 29,420 (294)
Rezafungin is a next-generation echinocandin that has favorable pharmacokinetic properties. We compared the occurrence of paradoxical growth (PG) and trailing effect (TE) characteristics to echinocadins with rezafungin, caspofungin, micafungin and ...
Zoltán Tóth+9 more
semanticscholar +1 more source
Cell wall composition and biofilm formation of azoles-susceptible and -resistant Candida glabrata strains [PDF]
In the present study, three strains of Candida glabrata have been investigated to shed light on the mechanisms involved in azole resistance during adherence and biofilm formation.
Angiolella, Letizia+6 more
core +5 more sources
Candida auris, what do paediatricians need to know? [PDF]
AW is supported by the Wellcome Trust Strategic Award (grant 097377) and the MRC Centre for Medical Mycology (grant MR/N006364/1) at the University of Aberdeen.Peer reviewedPublisher ...
Warris, Adilia
core +1 more source
Bioinspired Cationic Antimicrobial Polymers
A review about membrane active cationic polymers with antimicrobial properties. A focus is laid on polymeric architecture, stimuli‐responsive antimicrobial polymers, as well as synergistic effects of polymers, and other compounds. Abstract Antibiotics are an essential tool of modern medicine, which is critically endangered by the spread of ...
Heliya Javadi+2 more
wiley +1 more source
The Utilization Pattern of Caspofungin in an Educational Hospital
Background: Caspofungin is prescribed for the systemic treatment of fungal infections and its correct prescription pattern is an issue of importance. Hence in this study Caspofungin utilization and the frequency rate of medication errors were investigated at a training hospital in a developing country.
Mahin Jamshidi+8 more
openaire +3 more sources
Docking-based virtual screening of known drugs against murE of Mycobacterium tuberculosis towards repurposing for TB. [PDF]
Repurposing has gained momentum globally and become an alternative avenue for drug discovery because of its better success rate, and reduced cost, time and issues related to safety than the conventional drug discovery process.
Brindha, Sridharan+4 more
core +1 more source
Schematic illustration of prepared poly(DEAEMA‐co‐EMA)/PIN composities and 3D AFM image. Abstract In the current study, in the first stage, amphiphilic poly(2‐diethylamino ethylmethacrylate‐co‐ethyl methacrylate) [Poly(DEAEMA‐co‐EMA)] was synthesized from the 2‐diethylamino ethylmethacrylate (DEAEMA) and the ethyl methacrylate (EMA) using the free ...
Safiye Elif Korcan+4 more
wiley +1 more source
Combined antifungal resistance and biofilm tolerance: the global threat of Candida auris [PDF]
The enigmatic yeast Candida auris has emerged over the last decade and rapidly penetrated our consciousness. The global threat from this multidrug-resistant yeast has generated a call to arms from within the medical mycology community.
Kean, Ryan, Ramage, Gordon
core +2 more sources
Echinocandins show fungicidal activity against common invasive mycoses but are ineffective against cryptococcosis. The underlying mechanism for echinocandin resistance in Cryptococcus neoformans remains poorly understood but has been shown to involve ...
Chengjun Cao+4 more
doaj +1 more source
Oma1 Links Mitochondrial Protein Quality Control and TOR Signaling To Modulate Physiological Plasticity and Cellular Stress Responses [PDF]
ACKNOWLEDGMENTS We thank Dennis Winge (University of Utah) and the members of the Khalimonchuk laboratory for critical comments. We also thank Christoph Schuller (University of Natural Resources, Austria) and Paul Herman (Ohio State University) for ...
Barrientos, Antoni+10 more
core +2 more sources