Results 31 to 40 of about 3,043 (217)

Pedicularis L. Genus. Systematics, botany, phytochemistry, chemotaxonomy, ethnopharmacology, and other [PDF]

, 2019
In this review, the relevance of the plant species belonging to the Pedicularis L. genus has been considered from different points of view. Particular emphasis was given to phytochemistry and ethnopharmacology, since several classes of natural compounds ...
Bianco, Armandodoriano, Ciccòla, Alessandro, De Vita, Daniela, Foddai, Sebastiano, Franceschin, Marco, Frezza, Claudio, Guiso, Marcella, Nicoletti, Marcello, Serafini, Ilaria, Serafini, Mauro, Tomassini, Lamberto, Toniolo, Chiara, Venditti, Alessandro, Ventrone, Antonio   +13 more
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Enhancement of antiproliferative activity by molecular simplification of catalpol

Bioorganic & Medicinal Chemistry, 2010
Two iridoid scaffolds were synthesized enantioselectively using as key step an l-proline-catalyzed alpha-formyl oxidation. The in vitro antiproliferative activities were evaluated against a representative panel of human solid tumor cell lines. Both iridoids induced considerably growth inhibition in the range 0.38-1.86muM.
García, Celina, León, Leticia G., Pungitore, Carlos Rodolfo, Ríos Luci, Carla, Daranas, Antonio H., Montero, Juan C., Pandiella, Atanasio, Tonn, Carlos Eugenio, Martín, Víctor S., Padrón, José M.   +9 more
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Phenolic profiling of Veronica spp. grown in mountain, urban and sand soil environments [PDF]

, 2014
Veronica (Plantaginaceae) genus is widely distributed in different habitats. Phytochemistry studies are increasing because most metabolites with pharmacological interest are obtained from plants. The phenolic compounds of V. montana, V.
Barreira, João C.M., Dias, Maria Inês, Ferreira, Isabel C.F.R., Santos-Buelga, Celestino, Soković, Marina, Stojković, Dejan, Živković, Jelena   +6 more
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Antiangiogenic effects of catalpol on rat corneal�neovascularization

Molecular Medicine Reports, 2017
To investigate the effects of catalpol on corneal neovascularization (CNV) and associated inflammation, eye drops (5 mM catalpol or PBS) were administered four times daily to alkali‑burn rat models of CNV and inflammation. Clinical evaluations of CNV and the degree of inflammation were performed on days 0, 4, 7, 10 and 14 under slit lamp microscopy ...
Han, Yun, Shen, Mei, Tang, Li-Yuan, Tan, Gang, Yang, Qi-Chen, Ye, Lei, Ye, Lin-Hong, Jiang, Nan, Gao, Gui-Ping, Shao, Yi   +9 more
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Beneficial Effects of Catalpol Supplementation during In Vitro Maturation of Porcine Cumulus-Oocyte Complexes

Antioxidants, 2023
Oxidative stress degrades oocytes during in vitro maturation (IVM). Catalpol, a well-known iridoid glycoside, exhibits antioxidant, anti-inflammatory, and antihyperglycemic effects. In this study, catalpol supplementation was tested on porcine oocyte IVM
Yanxin Wang, Ye Xu, Sijia Li, Xi Yan, Xiaofen Yang, Mengjia Chen, Yun Wang, Ruru Jia, Dongping Zhou, Deshun Shi, Fenghua Lu   +10 more
doaj   +1 more source

RhoA/ROCK-2 Pathway Inhibition and Tight Junction Protein Upregulation by Catalpol Suppresses Lipopolysaccaride-Induced Disruption of Blood-Brain Barrier Permeability

Molecules, 2018
Lipopolysaccaride (LPS) directly or indirectly injures brain microvascular endothelial cells (BMECs) and damages the intercellular tight junction that gives rise to altered blood-brain barrier (BBB) permeability.
Shan Feng, Li Zou, Hongjin Wang, Ran He, Ke Liu, Huifeng Zhu   +5 more
doaj   +1 more source

Feasibility of Catalpol Intranasal Administration and Its Protective Effect on Acute Cerebral Ischemia in Rats via Anti-Oxidative and Anti-Apoptotic Mechanisms

Drug Design, Development and Therapy, 2022
Jinghui Wang,1 Yuhua Zhang,2 Meifeng Zhang,1 Si Sun,1 Yang Zhong,1 Lei Han,1 Yitong Xu,1 Dong Wan,3 Junhui Zhang,4 Huifeng Zhu1 1College of Pharmaceutical Sciences & College of Chinese Medicine, Southwest University, Chongqing, 400715, People’s Republic ...
Wang J, Zhang Y, Zhang M, Sun S, Zhong Y, Han L, Xu Y, Wan D, Zhang J, Zhu H   +9 more
doaj  

Biological Activities and Analytical Methods for Detecting Aucubin and Catalpol Iridoid Glycosides in Plantago Species: A Review Study [PDF]

Pharmaceutical and Biomedical Research, 2023
Background: Plantago species contain aucubin and catalpol iridoid glycosides used in traditional medicine for many purposes. Objectives: To accelerate the utilization of aucubin and catalpol in Plantago species, research should be focused on introducing ...
Samaneh Rahamouz-Haghighi
doaj  

Comparative analysis of specialized metabolites and antioxidant capacity in vitro of different natural populations of Globularia spp. [PDF]

, 2018
Total phenolic, flavonoid, condensed tannin and iridoid content, as well as antioxidant capacity in vitro, were determined spectrophotometrically in methanolic extracts of different plant parts of the Mediterranean medicinal plant Globularia alypum L ...
Albach, Altundag, Amessis, Arvouet, Blois, Boudet, Bouzabata, Broadhurst, Carrió, Chaudhuri, Chaudhuri, Chograni, Crkvenčić, Djeridane, Djeridane, Dobler, Eissa, Evans, Friščić, Ghasemzadeh, Guiche, Gurib, Harborne, Khlifi, Kirmizibekmez, Kirmizibekmez, Kirmizibekmez, Kraus, Leporatti, Natale, Pellegrini, Safi, Sertić, Singleton, Sipahi, Sun, Taghzouti, Taleb, Thetsrimuang, Toda, Touaibia, Trim, Tundis, Tundis, Tutin   +44 more
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Radio-protective effect of catalpol in cultured cells and mice [PDF]

Journal of Radiation Research, 2012
Ionizing radiation can induce DNA damage and cell death by generating reactive oxygen species (ROS). The objective of this study was to investigate the radio-protective effect of catalpol (a main bioactive component in the traditional Chinese Rehmannia) on irradiated cells and mice.
Chen, Chengjie, Chen, Zhe, Xu, Fang, Zhu, Chao, Fang, Fanfu, Shu, Shi, Li, Min, Ling, Changquan   +7 more
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