Results 41 to 50 of about 1,785 (172)
Biological Activities and Analytical Methods for Detecting Aucubin and Catalpol Iridoid Glycosides in Plantago Species: A Review Study [PDF]
Pharmaceutical and Biomedical Research, 2023 Background: Plantago species contain aucubin and catalpol iridoid glycosides used in traditional medicine for many purposes. Objectives: To accelerate the utilization of aucubin and catalpol in Plantago species, research should be focused on introducing ...
Samaneh Rahamouz-Haghighi
doaj
Radio-protective effect of catalpol in cultured cells and mice [PDF]
Journal of Radiation Research, 2012 Ionizing radiation can induce DNA damage and cell death by generating reactive oxygen species (ROS). The objective of this study was to investigate the radio-protective effect of catalpol (a main bioactive component in the traditional Chinese Rehmannia) on irradiated cells and mice.
Chen, Chengjie +7 more
openaire +2 more sources
Molecules, 2018 Lipopolysaccaride (LPS) directly or indirectly injures brain microvascular endothelial cells (BMECs) and damages the intercellular tight junction that gives rise to altered blood-brain barrier (BBB) permeability.
Shan Feng +5 more
doaj +1 more source
Cells, 2021 Oxidative damage to retinal pigment epithelial (RPE) has been identified as one of the major regulatory factors in the pathogenesis of age-related macular degeneration (AMD).
Longtai You +10 more
doaj +1 more source
BMC Plant Biology, 2023 Background Rehmannia glutinosa is a rich source of terpenoids with a high medicinal reputation. The present study compared dedifferentiated cells (DDCs) and cambial meristematic cells (CMCs) cell cultures of R.
Pengfei Zhou +11 more
doaj +1 more source
Determination of Aucubin and Catalpol in Plantago Species by Micellar Electrokinetic Chromatography [PDF]
Zeitschrift für Naturforschung C, 2004 Micellar electrokinetic chromatography (MEKC) was used for the separation and determination of two iridoid glycosides, aucubin and catalpol, in several Plantago species growing in Croatia: P. altissima L., P. argentea Chaix, P. coronopus L., P. holosteum Scop. (subsp. depauperata, subsp. holosteum and subsp. scopulorum), P. lagopus L., P. lanceolata L.,
Vladimir-Knežević, Sanda +3 more
openaire +4 more sources
Catalpol Exerts a Neuroprotective Effect in the MPTP Mouse Model of Parkinson’s Disease
Frontiers in Aging Neuroscience, 2019 The degeneration of dopaminergic (DA) neurons in Parkinson’s disease (PD) is related to inflammation and oxidative stress. Anti-inflammatory agents could reduce the risk or slow the progression of PD.
Li-Yuan Wang +6 more
doaj +1 more source
Pharmaceutical Biology, 2022 Context Catalpol is a major bioactive constituent of Rehmannia glutinosa Libosch (Scrophulariaceae), a traditional Chinese medicine, which is widely used in multiple diseases, including hypertension.Objectives To explore whether catalpol protects against
Yu Xia +3 more
doaj +1 more source
The Endothelial CXCR Family in Vascular Health and Disease
iNew Medicine, EarlyView.ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Ajugol Improves Liver Fibrosis by Modulating Bile Acid and Arachidonic Acid Metabolism in Mice
Phytotherapy Research, EarlyView.Ajujol ameliorates hepatic fibrosis by regulating bile acid metabolism and suppressing inflammatory responses. ABSTRACT Ajugol (AJ), the primary component extracted from the root of Rehmannia glutinosa, exhibits protective effects against metabolic dysregulation and chronic inflammation.
Xia Wei +9 more
wiley +1 more source