Environmental heterogeneity drives remarkable metabolic plasticity in Rubia cordifolia with significant variation in nutritional constituents, phytochemicals, bioactive compounds, and antioxidant activity among natural populations. High‐altitude populations exhibited higher accumulation of phenolics, flavonoids, alizarin, mollugin, and antioxidant ...
Deepti Tiwari +5 more
wiley +1 more source
B. macrophylla leaf ethyl acetate fractionated extract exhibits the highest TPC, very strong radical‐scavenging activities, and the highest SPF value of 28.64 ± 0.51. LC‐MS analysis identifies m‐trigallic acid, cis‐coutaric acid, and ellagic acid, which may contribute to its bioactivities. The present work highlights B.
Wei Lee Chong +7 more
wiley +1 more source
Epigenetic Regulation of Divergent Co-Expression Between Whole-Genome Duplication and Transposed Duplication Genes and Its Impact on Catechin Accumulation in <i>Camellia sinensis</i>. [PDF]
Lian S +6 more
europepmc +1 more source
Ethanol–water extraction followed by 5 kDa ultrafiltration yields a bixin‐rich annatto extract with 97.9% bixin rejection, 94.2% recovery in the retentate, and an enrichment factor of 1.29. Fouling analysis indicates an important contribution from cake formation, highlighting the role of membrane–solute interactions in the selective concentration of ...
Karolyna B. Miguel +2 more
wiley +1 more source
Targeting PPARγ-NF-κB: (+)-catechin reverses <i>Clostridioides difficile</i> toxin A-induced intestinal barrier dysfunction. [PDF]
Li S, Luan Y, Li Z, Lu Y, Lai D, Chen K.
europepmc +1 more source
Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina
Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella +2 more
wiley +1 more source
Utilization of Guarana Agroindustrial Waste as a Source of Antimicrobial Compounds for Human Pathogenic Bacterial Removal in Wastewater Sample. [PDF]
Dos Santos EO +4 more
europepmc +1 more source
Systems Pharmacology and Multitarget Modulation of Letrozole–HFD‐Induced Polycystic Ovarian Syndrome by Fruit Pulp of Prunus armeniaca [PDF]
Integrated systems pharmacology and in vivo evaluation reveal that hydroalcoholic extract of fruit pulp of Prunus armeniaca (HAE of FPPA) ameliorates letrozole–HFD‐induced PCOS through multitarget modulation. Network analysis identifies 105 shared targets enriched in PI3K/Akt, MAPK, HIF‐1, and inflammatory pathways, while treatment improves hormonal ...
Priya R +4 more
europepmc +2 more sources
Human‐umbilical‐cord‐mesenchymal‐stem‐cell‐derived exosomes amplify anti‐hepatocellular‐carcinoma effects of gallic acid from Compound Muji Granules. This work identifies absorbed herbal constituents and reveals modulation of IL‐17/MAPK/p53 signaling in HCC organoid models, offering mechanistic insights for exosome‐assisted traditional‐medicine ...
Qiang Zhang +12 more
wiley +1 more source
Green Tea Extract Attenuates Oxidative Stress and Prolongs Red Blood Cell Survival in Iron-Overloaded β-Thalassemic Mice. [PDF]
Zhong Y +9 more
europepmc +1 more source

