Results 1 to 10 of about 34,062 (265)

Enhancement of Statin Effects on Lipid Lowering and Reduction of Cardiovascular Risk Score by (−)‐Epicatechin in Proof‐of‐Concept Pilot Study

Clinical and Translational Science
Statins play an instrumental role in reducing and managing atherosclerotic cardiovascular disease (ASCVD) but can be difficult to tolerate due to muscle‐associated side effects. There remains an unmet need for strategies that improve statin tolerance and
Cameron K. Ormiston, Aryana Pazargadi, Ashley Rosander, Guillermo Ceballos, Francisco Villarreal, Pam R. Taub   +5 more
doaj   +1 more source

Levels of phenolic acids, catechin and epicatechin in wines of Portugal and the Azores prodece from different varieties and vintages

OENO One, 2006
In recent decades, epidemiological studies have shown that the incidence of cardiovascular disease is less frequent in countries where wine is regularly consumed in moderate amounts.
María Teresa Ribeiro de Lima, Mary T. Kelly, Marie-Thérèse Cabanis, Alain Blaise   +3 more
doaj   +1 more source

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

Phytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao, Huiming Huang, Xuejiao Wei, Xiaoxue Wang, Wanying Xie, Xinyu Qiu, Fei Wang, Zhuguo Wang, Ruoxin Zhang, Yilin Cai, Changhai Qu, Zhongdong Hu   +11 more
wiley   +1 more source

Unravelling polyphenol skin permeation: A comparative study using full‐thickness 3D in vitro and ex vivo human skin models

International Journal of Cosmetic Science, EarlyView.
This study demonstrates that full‐thickness 3D in vitro skin models reliably assess the permeation of cosmetic polyphenols, revealing compound‐specific transport profiles and bridging the gap between conventional cell models and ex vivo human skin, while offering an ethical and robust alternative for dermal absorption screening. Abstract The evaluation
Mariana Marques, Filipa Teixeira, Mónica Vieira, M. Helena Amaral, Paulo C. Costa, Stefano Dall'Acqua, Francisca Rodrigues   +6 more
wiley   +1 more source

Separation Technique of Tannins and Caffeine in Black Tea Using Modified Microwave-Assisted Extraction and High-Performance Liquid Chromatography

International Journal of Technology
Black tea is known to contain condensed tannins including catechin (C), epicatechin (EC), and epigallocatechin gallate (EGCG), as well as caffeine (CAF). Some consumers of specific diets avoid consuming tannins or CAF.
Meyliana Wulandari, Zahratussaadah Zahratussaadah, Andreas Andreas, Roza Adriany, Nofrizal Nofrizal, Mardiana Saaid, Javier Urraca   +6 more
doaj   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Impact of Epicatechin on the Oxidation Behavior of Fish Oil during Gastrointestinal Digestion

Shipin gongye ke-ji
O/W fish oil emulsions with varying EPA/DHA ratios (6/1, 5/2, 4/3) were prepared based on an in vitro digestion-oxidation model. The effects of epicatechin (EC) on the changes in lipid hydroperoxides (LPO), thiobarbituric acid reactive substances (TBARS),
Yizhuo FAN, Liyan ZHANG, Qiyue YANG, Yehui ZHANG, Wenjuan JIAO   +4 more
doaj   +1 more source

Tonoplast‐Localized ABCC Transporters Enhance Heterologous Production of the Antidiabetic Montbretin A and Its Analogues in Nicotiana benthamiana

Plant Biotechnology Journal, EarlyView.
ABSTRACT The plant‐derived specialized metabolite montbretin A (MbA) is under development as an improved treatment for Type 2 diabetes, a worldwide epidemic. MbA is an acylated flavonol glycoside so far only found in small amounts in montbretia (Crocosmia × crocosmiiflora) corms.
Charlotte Hijmans, Filipe Cabrita Cruz, Lars H. Kruse, Joerg Bohlmann, Sandra Irmisch   +4 more
wiley   +1 more source

Integrated Analysis of Grapevine Responses to Winter Pruning Reveals Temperature‐Associated, Polyphenol‐Rich Xylem Occlusions

Plant, Cell &Environment, EarlyView.
ABSTRACT Perennial crops are continually wounded throughout cultivation. To limit pathogen infection and tissue dehydration, plants have evolved a range of wound responses that protect damaged tissues. These responses include changes in gene expression and the synthesis of protective compounds such as polyphenols.
Marilou Camboué, Monica Galar‐Martínez, Grégoire Loupit, Paraskevi Charalambous, Enric Zehraoui, Joseph Tran, Josep Valls Fonayet, Luis Gonzaga Santesteban, Notburga Gierlinger, Sarah Jane Cookson   +9 more
wiley   +1 more source

Cytokinins Promote Rust Susceptibility in Poplar by Suppressing Defence Signalling, Reducing Defence Accumulation and Reprogramming Primary Metabolism

Plant, Cell &Environment, EarlyView.
ABSTRACT Cytokinins (CKs), classically recognised as plant growth regulators, are increasingly implicated in plant‐microbe interactions. Studies in herbaceous plants suggest that CKs can function as signalling molecules with dual roles in plant defence, either restricting or facilitating pathogen infection.
Chhana Ullah, Ahalya Rajendran, Sarrin Shahadat, Michael Reichelt, Almuth Hammerbacher, Jonathan Gershenzon   +5 more
wiley   +1 more source