Results 41 to 50 of about 47,174 (243)

Computational and In Vitro Investigation of (-)-Epicatechin and Proanthocyanidin B2 as Inhibitors of Human Matrix Metalloproteinase 1

Biomolecules, 2020
Matrix metalloproteinases 1 (MMP-1) energetically triggers the enzymatic proteolysis of extracellular matrix collagenase (ECM), resulting in progressive skin aging.
Kyung Eun Lee, Shiv Bharadwaj, Umesh Yadava, Sang Gu Kang   +3 more
doaj   +1 more source

Cations and Phenolic Compounds Concentrations in Fruits of Fig Plants Exposed to Moderate Levels of Salinity

Antioxidants, 2021
Fig trees are often grown in areas affected by salinity problems. We investigated changes in the concentrations of 15 phenolic compounds and mineral elements (Mg, Ca, K, Zn, Cu, Mn, Mo, Fe, Na) in fruits of fig plants (Ficus carica L. cv.
Alessandra Francini, Mirko Sodini, Giulia Vicario, Andrea Raffaelli, Riccardo Gucci, Giovanni Caruso, Luca Sebastiani   +6 more
doaj   +1 more source

Impact of epicatechin on fibrin clot structure

European Journal of Pharmacology, 2021
Fibrin clot structure and function are major determinants of thromboembolic diseases. The study aim was to determine the impact of epicatechin (a flavonoid with cardiovascular protective effects) on fibrin clot structure and permeability. Plasma samples from 12 healthy subjects were incubated with increasing concentrations of epicatechin.
Sinegre, Thomas, Milenkovic, Dragan, Teissandier, Dorian, Fully, Pauline, Bourdin, Julien, Morand, Christine, Lebreton, Aurélien   +6 more
openaire   +5 more sources

Integrated Multi-Omic Analyses of the Genomic Modifications by Gut Microbiome-Derived Metabolites of Epicatechin, 5-(4′-Hydroxyphenyl)-γ-Valerolactone, in TNFalpha-Stimulated Primary Human Brain Microvascular Endothelial Cells

Frontiers in Neuroscience, 2021
Cerebral blood vessels are lined with endothelial cells and form the blood-brain barrier. Their dysfunction constitutes a crucial event in the physiopathology of neurodegenerative disorders and cognitive impairment.
Karla Fabiola Corral-Jara, Saivageethi Nuthikattu, John Rutledge, Amparo Villablanca, Christine Morand, Hagen Schroeter, Dragan Milenkovic, Dragan Milenkovic   +7 more
doaj   +1 more source

Metabolic profile and root development of Hypericum perforatum L. in vitro roots under stress conditions due to chitosan treatment and culture time [PDF]

, 2016
The responses of Hypericum perforatum root cultures to chitosan elicitation had been investigated through 1H-NMR-based metabolomics associated with morpho-anatomical analyses.
Alessio eValletta, Alfredo eMiccheli, Elisa eBrasili, Fabio eSciubba, Federico eMarini, Gabriella ePasqua, Giulia ePraticò, Maria Enrica eDi Cocco, Maria Enrica eDi Cocco, Noemi eTocci, Valdir eCechinel-Filho, Valdir eCechinel-Filho   +11 more
core   +2 more sources

Anthocyanins inhibit tumor necrosis alpha-induced loss of Caco-2 cell barrier integrity [PDF]

, 2017
An increased permeability of the intestinal barrier is proposed as a major event in the pathophysiology of conditions characterized by chronic gut inflammation.
Anderson, Maureen, Cremonini, Eleonora, Fraga, César Guillermo, Hester, Shelly N., Mastaloudis, Angela, Oteiza, Patricia Isabel, Verstraeten, Sandra Viviana, Waterhouse, Andrew L., Wood, Steven M.   +8 more
core   +1 more source

Antioxidant processes involving epicatechin decreased symptoms of pine wilt disease

Frontiers in Plant Science, 2022
Since the pine wood nematode (PWN, Bursaphelenchus xylophilus) invasion of Northeast China, both symptomatic and asymptomatic PWN carriers have been found. Asymptomatic PWN carriers, which are more dangerous than symptomatic carriers, constitute a source
Ruizhi Zhang, Jianan Wang, Rui Xia, Danlei Li, Feng Wang, Feng Wang   +5 more
doaj   +1 more source

Searching for new sources of innovative products for the food industry within halophyte aromatic plants: In vitro antioxidant activity and phenolic and mineral contents of infusions and decoctions of Crithmum maritimum L. [PDF]

, 2017
Aromatic halophyte plants are an outstanding source of bioactive compounds and natural products with potential use in the food industry. This work reports the in vitro antioxidant activity, toxicity, poly phenolic profile and mineral contents of ...
Barreira, Luísa, Custódio, Luísa, Florencio Nogueira, Jose Manuel, Marques, Catia, Neng, Nuno da Rosa, Pereira, Catarina Guerreiro, Santos, Tamara, Varela, J.   +7 more
core   +1 more source

Study of Influence of Extraction Method on the Recovery Bioactive Compounds from Peel Avocado

Molecules, 2023
The avocado peel is a waste material from consumption avocado (Persea americana Mill.) with big biotechnology potential. The purpose of the present work was to study the influence of six extraction methods, maceration (M), maceration plus β-cyclodextrin (
Emir Martínez-Gutiérrez
doaj   +1 more source

Formation of A-type anthocyanin-epicatechin dimers by model reactions of anthocyanin extracts and epicatechin

LWT, 2021
Abstract A-type proanthocyanidins (PACs) with health benefits such as prevention of urinary-tract infections are less common in food. Anthocyanins can directly condense with epicatechins to give rise to A-type anthocyanin-epicatechin dimers linked by C4–C8 and C2–O–C7 bonds, analogues of A-type PACs.
Wei Li, Jiahao Yu, Jian Zhang, Lianfu Zhang   +3 more
openaire   +1 more source