Results 11 to 20 of about 34,062 (265)

Effects of (-)-epicatechin on mitochondria. [PDF]

Nutrition Reviews, 2020
Mitochondrial dysfunction is observed in a broad range of human diseases, including rare genetic disorders and complex acquired pathologies. For this reason, there is increasing interest in identifying safe and effective strategies to mitigate ...
Heyman, Elsa, Burelle, Yan, Daussin, Frédéric   +2 more
core   +8 more sources

Epicatechin oligomers longer than trimers have anti-cancer activities, but not the catechin counterparts

Scientific Reports, 2017
Since procyanidins (oligomeric catechin or epicatechin) were reported to exhibit health benefits, much attention has been paid to the synthesis of these compounds, especially those that are longer than trimers.
Kohki Takanashi, Manato Suda, Kiriko Matsumoto, Chisato Ishihara, Kazuya Toda, Koichiro Kawaguchi, Shogo Senga, Narumi Kobayashi, Mikihiro Ichikawa, Miyuki Katoh, Yasunao Hattori, Sei-ichi Kawahara, Koji Umezawa, Hiroshi Fujii, Hidefumi Makabe   +14 more
doaj   +2 more sources

Impact of Epicatechin on the Procoagulant Activities of Microparticles [PDF]

Nutrients, 2020
International audienceMicroparticles play a role in cardiovascular disease pathology. The flavanol-like epicatechin is increasingly considered due to its cardioprotective effects.
Bourgne, Céline, Nasri, Yosra, Louis-Thomas Dannus, Dannus, Louis-Thomas, Céline Bourgne, Bourgne, C., Morand, Christine, Yosra Nasri, Teissandier, D., Milenkovic, Dragan, Lebreton, Aurélien, Aurélien Lebreton, Teissandier, Dorian, Sinègre, T., Sinegre, Thomas, Dannus, L.T., Dorian Teissandier, Lebreton, A., Dragan Milenkovic, Nasri, Y., Thomas Sinegre, Christine Morand   +21 more
core   +7 more sources

Evaluation of (−)-epicatechin metabolites as recovery biomarker of dietary flavan-3-ol intake [PDF]

Scientific Reports, 2019
Data from dietary intervention studies suggest that intake of (−)-epicatechin mediates beneficial vascular effects in humans. However, population-based investigations are required to evaluate associations between habitual intake and health and these ...
Javier I. Ottaviani, Reedmond Fong, Jennifer Kimball, Jodi L. Ensunsa, Nicola Gray, Anna Vogiatzoglou, Abigail Britten, Debora Lucarelli, Robert Luben, Philip B. Grace, Deborah H. Mawson, Amy Tym, Antonia Wierzbicki, A. David Smith, Nicholas J. Wareham, Nita G. Forouhi, Kay-Tee Khaw, Hagen Schroeter, Gunter G. C. Kuhnle   +18 more
doaj   +11 more sources

Impact of epicatechin on fibrin clot structure

European Journal of Pharmacology, 2021
International audienceFibrin clot structure and function are major determinants of thromboembolic diseases. The study aim was to determine the impact of epicatechin (a flavonoid with cardiovascular protective effects) on fibrin clot structure and ...
Milenkovic, Dragan, Lebreton, Aurélien, Teissandier, Dorian, Sinegre, Thomas, Fully, Pauline, Morand, Christine, Bourdin, Julien   +6 more
core   +6 more sources

Therapeutic uses of epicatechin in diabetes and cancer [PDF]

Veterinary World, 2017
Epicatechin is a natural flavonoid found in green tea. It has been reported to possess an immense antioxidant effect which contributes to its therapeutic effect against a handful of ailments.
Layth Abdulmajeed Abdulkhaleq, Mohammed Abdulrazzaq Assi, Mohd Hezmee Mohd Noor, Rasedee Abdullah, Mohd Zamri Saad, Yun Hin Taufiq-Yap   +5 more
doaj   +4 more sources

Metabolization of Flavan‐3‐ol Oligomers by Eggerthella lenta, a Human Gut Bacterium [PDF]

Molecular Nutrition &Food Research, Volume 70, Issue 19, 15 October 2026.
Novel human gut bacterial strains were isolated and characterized for their ability to metabolize flavan‐3‐ols. While Eggerthella lenta and Flavonifractor plautii metabolized flavan‐3‐ol monomers, only E. lenta converted B‐ and A‐type procyanidins, demonstrating that this gut bacterium can metabolize flavan‐3‐ol oligomers.
Ruben Halifa, Claire Dufour, Agnes Cornu, Philippe Ruiz, Jeanne Danon, Christian Ginies, Michel Dubourdeaux, Sophie Comtet‐Marre, Pierre Peyret, Carine Le Bourvellec, Pascale Mosoni   +10 more
wiley   +2 more sources

Protective effects of epicatechin on the oxidation and N-nitrosamine formation of oxidatively stressed myofibrillar protein

International Journal of Food Properties, 2019
The present study investigated the protective effects of the polyphenol epicatechin on the protein structural changes, gel properties and N-nitrosodiethylamine (NDEA) formation of oxidatively stressed myofibrillar protein (MP).
Ling Li, Hui Ji
doaj   +2 more sources

Phytochemical Analysis of Moroccan Mercurialis annua L. and Its Nephroprotective Activity: Evidence Supporting Traditional Renal Uses [PDF]

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Mercurialis annua L.: Phytochemistry and Nephroprotective Activity. ABSTRACT Mercurialis annua L. (Euphorbiaceae) is traditionally used to treat renal disorders, although its nephroprotective activity remains poorly documented. This study characterized the phytochemical profile of the Moroccan hydroethanolic extract by UHPLC–ESI/MS, evaluated its acute
Abdeljalil Elmahdaoui, Manal Zefzoufi, Lansine Diakité, Mohammed Haida, Rabiaa Fdil, Aziz Auhmani, Stefania Garzoli, Zahra Sokar   +7 more
wiley   +2 more sources

Uptake and metabolism of (−)-epicatechin in endothelial cells

Archives of Biochemistry and Biophysics, 2018
Accumulating evidence suggest that diets rich in cocoa flavanols may have beneficial effects on cardiovascular health. The major cocoa flavanol monomer, (−)-epicatechin (EC), is readily absorbed and circulates primarily as glucuronidated, sulfated, and O-
Cortese-Krott, Miriam, Toro-Funes, Natalia, Heiss, Christian, Rodriguez-Mateos, Ana, Spencer, Jeremy P.E., Cifuentes-Gomez, Tania   +5 more
core   +5 more sources