Results 11 to 20 of about 31,210 (261)

Therapeutic uses of epicatechin in diabetes and cancer [PDF]

Veterinary World, 2017
Epicatechin is a natural flavonoid found in green tea. It has been reported to possess an immense antioxidant effect which contributes to its therapeutic effect against a handful of ailments.
Layth Abdulmajeed Abdulkhaleq, Mohammed Abdulrazzaq Assi, Mohd Hezmee Mohd Noor, Rasedee Abdullah, Mohd Zamri Saad, Yun Hin Taufiq-Yap   +5 more
doaj   +4 more sources

Effects of (−)-epicatechin on mitochondria [PDF]

Nutrition Reviews, 2020
Abstract Mitochondrial dysfunction is observed in a broad range of human diseases, including rare genetic disorders and complex acquired pathologies. For this reason, there is increasing interest in identifying safe and effective strategies to mitigate mitochondrial impairments. Natural compounds are widely used for multiple indications,
Daussin, Frédéric, Heyman, Elsa, Burelle, Yan   +2 more
openaire   +9 more sources

Impact of Epicatechin on the Procoagulant Activities of Microparticles [PDF]

Nutrients, 2020
Microparticles play a role in cardiovascular disease pathology. The flavanol-like epicatechin is increasingly considered due to its cardioprotective effects. The aim of this study was to investigate the impact of epicatechin on microparticle generation, phenotype and procoagulant properties.
Thomas Sinegre, Dragan Milenkovic, Céline Bourgne, Dorian Teissandier, Yosra Nasri, Louis-Thomas Dannus, Christine Morand, Aurélien Lebreton   +7 more
openaire   +6 more sources

Epicatechin oligomers longer than trimers have anti-cancer activities, but not the catechin counterparts

Scientific Reports, 2017
Since procyanidins (oligomeric catechin or epicatechin) were reported to exhibit health benefits, much attention has been paid to the synthesis of these compounds, especially those that are longer than trimers.
Kohki Takanashi, Manato Suda, Kiriko Matsumoto, Chisato Ishihara, Kazuya Toda, Koichiro Kawaguchi, Shogo Senga, Narumi Kobayashi, Mikihiro Ichikawa, Miyuki Katoh, Yasunao Hattori, Sei-ichi Kawahara, Koji Umezawa, Hiroshi Fujii, Hidefumi Makabe   +14 more
doaj   +2 more sources

Evaluation of (−)-epicatechin metabolites as recovery biomarker of dietary flavan-3-ol intake

Scientific Reports, 2019
Data from dietary intervention studies suggest that intake of (−)-epicatechin mediates beneficial vascular effects in humans. However, population-based investigations are required to evaluate associations between habitual intake and health and these ...
Javier I. Ottaviani, Reedmond Fong, Jennifer Kimball, Jodi L. Ensunsa, Nicola Gray, Anna Vogiatzoglou, Abigail Britten, Debora Lucarelli, Robert Luben, Philip B. Grace, Deborah H. Mawson, Amy Tym, Antonia Wierzbicki, A. David Smith, Nicholas J. Wareham, Nita G. Forouhi, Kay-Tee Khaw, Hagen Schroeter, Gunter G. C. Kuhnle   +18 more
doaj   +2 more sources

Impact of epicatechin on fibrin clot structure

European Journal of Pharmacology, 2021
Fibrin clot structure and function are major determinants of thromboembolic diseases. The study aim was to determine the impact of epicatechin (a flavonoid with cardiovascular protective effects) on fibrin clot structure and permeability. Plasma samples from 12 healthy subjects were incubated with increasing concentrations of epicatechin.
Sinegre, Thomas, Milenkovic, Dragan, Teissandier, Dorian, Fully, Pauline, Bourdin, Julien, Morand, Christine, Lebreton, Aurélien   +6 more
openaire   +6 more sources

Protective effects of epicatechin on the oxidation and N-nitrosamine formation of oxidatively stressed myofibrillar protein

International Journal of Food Properties, 2019
The present study investigated the protective effects of the polyphenol epicatechin on the protein structural changes, gel properties and N-nitrosodiethylamine (NDEA) formation of oxidatively stressed myofibrillar protein (MP).
Ling Li, Hui Ji
doaj   +2 more sources

Uptake and metabolism of (−)-epicatechin in endothelial cells

Archives of Biochemistry and Biophysics, 2014
Accumulating evidence suggest that diets rich in cocoa flavanols may have beneficial effects on cardiovascular health. The major cocoa flavanol monomer, (-)-epicatechin (EC), is readily absorbed and circulates primarily as glucuronidated, sulfated, and O-methylated metabolites in human plasma.
Rodriguez-Mateos, Ana, Toro-Funes, Natalia, Cifuentes-Gomez, Tania, Cortese-Krott, Miriam, Heiss, Christian, Spencer, Jeremy P.E.   +5 more
openaire   +5 more sources

ERYTHROCYTE SODIUM/HYDROGEN EXCHANGE INHIBITION BY (−) EPICATECHIN

Cell Biology International, 2001
Epicatechin, a flavonoid belonging to the group of compounds collectively called catechins, have been reported to possess insulin‐like properties. Besides their anti‐diabetic properties, catechins also show growth inhibition. Since cytosolic pH (pHi) plays a role in cell proliferation and the Na/H exchanger (NHE) is the major pH (pHi) regulatory ...
MATTEUCCI, ELENA, RIZVI S. I., GIAMPIETRO, OTTAVIO   +2 more
openaire   +4 more sources

Production of deuterium labelled (−)-epicatechin in a microreactor

Chemical Engineering Journal, 2011
Green tea catechins have been reported to have multiple health benefits. To understand their metabolic and toxicological interactions in the human body studies need to be undertaken using stable isotope labelled compounds, but they can be time consuming and expensive.
Betts, Jonathan W., Haswell, Stephen J., Kelly, Stephen M., Kitney, Stuart P., Fu, Yiton, Peng, Wei Min, Peng, Wei-Min   +6 more
openaire   +4 more sources