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Obesity and Natural Products: Mechanisms, Therapeutic Potential, and Future Directions

open access: yesFood Science &Nutrition, Volume 14, Issue 3, March 2026.
Natural products such as EGCG, berberine, curcumin, and capsaicin modulate key metabolic pathways including AMPK activation, adipogenesis inhibition, and inflammatory signaling. While clinical trials demonstrate modest benefits on body weight and metabolic parameters, translational challenges related to bioavailability, dose feasibility, and regulatory
Ohoud M. Marie   +1 more
wiley   +1 more source

Salvadora persica Fruit Methanolic Extract, Nutritional Profiling, Therapeutic Potential in High‐Fat Diet‐Induced Hyperlipidemic Rats: In Vivo, In Vitro, and In Silico Approaches

open access: yesFood Science &Nutrition, Volume 14, Issue 3, March 2026.
Salvadora persica methanolic extract exhibited strong antioxidant, hypolipidemic, and hypoglycemic effects in high‐fat diet‐induced hyperlipidemic rats. In vitro antioxidant assays, GC–MS profiling, and in vivo studies confirmed improvements in the lipid profile and in markers of oxidative stress, liver, and kidney function.
Nudrat Khursheed   +10 more
wiley   +1 more source

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