Results 11 to 20 of about 10,779 (272)
p120 Catenin-Associated Fer and Fyn Tyrosine Kinases Regulate β-Catenin Tyr-142 Phosphorylation and β-Catenin-α-Catenin Interaction [PDF]
Molecular and Cellular Biology, 2003 beta-Catenin has a key role in the formation of adherens junction through its interactions with E-cadherin and alpha-catenin. We show here that interaction of beta-catenin with alpha-catenin is regulated by the phosphorylation of beta-catenin Tyr-142. This residue can be phosphorylated in vitro by Fer or Fyn tyrosine kinases.
Jose, Piedra +6 more
openaire +4 more sources
Adhesion molecules in Wilms tumor (part I) [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2003 Adhesion molekues are glicoprotees which have extracellular, transmembranous and intracytoplasmatic part. They show their basic role is in cell interaction in the tissue on one side and between cells and matrix on the other side.
Basta-Jovanović Gordana M. +2 more
doaj +1 more source
JHEP Reports, 2023 Background & Aims: β-catenin is a well-known effector of the Wnt pathway, and a key player in cadherin-mediated cell adhesion. Oncogenic mutations of β-catenin are very frequent in paediatric liver primary tumours.
Caroline Gest +19 more
doaj +1 more source
Journal of the American Society of Nephrology, 2011 Congenital anomalies of the kidney and urinary tract are the single most common cause of renal failure in childhood. Advances in the care of children with renal failure has primarily focused on optimizing the supportive, although nonspecific, treatment of chronic kidney disease and in addressing ...
Jacqueline Ho, Carlton M. Bates
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The potential involvement of E-cadherin and beta-catenins in meningioma. [PDF]
PLoS ONE, 2010 OBJECTIVE: To investigate the potential involvements of E-cadherin and beta-catenin in meningioma. METHODS: Immunohistochemistry staining was performed on samples from patients with meningioma.
Keiyu Zhou +5 more
doaj +1 more source
Functions of p120ctn isoforms in cell-cell adhesion and intracellular signaling [PDF]
, 2012 The functions of many organs depend on the generation of an epithelium. The transition from a set of loosely connected nonpolarized cells to organized sheets of closely associated polarized epithelial cells requires the assembly of specialized cell ...
Pieters, Tim +2 more
core +2 more sources
Expression of the E-cadherin-catenin complex in patients with pancreatic ductal adenocarcinoma.
Folia Histochemica et Cytobiologica, 2010 Cadherins and catenins, mediators of intercellular interactions, play a major role in adhesion. Changes in their expression and functioning reflect invasive and metastatic properties of cancer cells.
Katarzyna Guzińska-Ustymowicz +3 more
doaj +1 more source
Plakophilin-3 catenin associates with the ETV1/ER81 transcription factor to positively modulate gene activity. [PDF]
PLoS ONE, 2014 Members of the plakophilin-catenin sub-family (Pkp-1, -2, and -3) facilitate the linkage of desmosome junctional components to each other (e.g. desmosomal cadherins to desmoplakin) and the intermediate-filament cytoskeleton.
William A Munoz +9 more
doaj +1 more source
Scribble, Lgl1, and myosin IIA interact with α-/β-catenin to maintain epithelial junction integrity
Cell Adhesion & Migration, 2023 E-cadherin-catenin complex together with the cytoskeleton, builds the core of Adherens junctions (AJs). It has been reported that Scribble stabilizes the coupling of E-cadherin with catenins promoting epithelial cell adhesion, but the mechanism remains ...
Maha Abedrabbo +4 more
doaj +1 more source
Functions of p120ctn in development and disease [PDF]
, 2012 p120 catenin (p120ctn), a component of the cadherin-catenin complex, was the first member to be identified in a most interesting subfamily of the Armadillo family. Several p120ctn isoforms are generated by alternative splicing.
Pieters, Tim +2 more
core +1 more source