Results 21 to 30 of about 1,070 (170)
Molecules, 2023 Catharanthus roseus is a medicinal plant that produces indole alkaloids, which are utilized in anticancer therapy. Vinblastine and vincristine, two commercially important antineoplastic alkaloids, are mostly found in the leaves of Catharanthus roseus.
Hossam S. El-Beltagi +11 more
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BMC Plant Biology, 2007 Background Elicitations are considered to be an important strategy towards improved in vitro production of secondary metabolites. In cell cultures, biotic and abiotic elicitors have effectively stimulated the production of plant secondary metabolites ...
Chelliah Jayabaskaran, Ramani Shilpa
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Attempted Synthesis of Vinca Alkaloids Condensed with Three-Membered Rings
Molecules, 2018 Our successful work for the synthesis of cyclopropanated vinblastine and its derivatives by the Simmons–Smith reaction was followed to build up further three-membered rings into the 14,15-position of the vindoline part of the dimer alkaloid ...
András Keglevich +8 more
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Spatial transcriptomics drives a new era in plant research
The Plant Journal, Volume 116, Issue 6, Page 1571-1581, December 2023., 2023 SUMMARY The plant community lags far behind the animal and human fields concerning the application of single‐cell methodologies. This is primarily due to the challenges associated with plant tissue dissection and the limitations of the available technologies.
Ruilian Yin, Keke Xia, Xun Xu
wiley +1 more source
Catharanthus roseus (L.) G. Don - plant regeneration and alkaloids content
Acta Societatis Botanicorum Poloniae, 2014 We describe here a regeneration of plantlets of Catharanthus roseus (L.) G. Don from shoot tips and axillary buds. Shoot tips were excised from 7-day-old seedlings and were incubated in solid Nitsch and Nitsch (NN) medium supplemented with kinetin ...
Mirosława Furmanowa +3 more
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Addition of Vindoline to p-Benzoquinone: Regiochemistry, Stereochemistry and Symmetry Considerations
Molecules, 2021 Vindoline and catharanthine are the major alkaloids of Catharanthus roseus and are extracted in large quantities to prepare the pharmaceutically important Vinca type alkaloids vincaleukoblastine, vincristine and navelbine.
Shamsher Ali +3 more
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Molecules, 2007 Dried leaves of Catharanthus roseus were extracted with aqueous acidic 0.1 M solution of HCl. Alkaloid-embonate complexes were obtained as precipitates by treating the extract with an alkaline (NaOH) solution of embonic acid (4,4-methylene-bis-3 ...
Marja-Liisa Riekkola +4 more
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Stereochemical insights into sarpagan and akuammiline alkaloid biosynthesis. [PDF]
New PhytolSummary Sarpagan and akuammiline monoterpenoid indole alkaloids (MIAs) are a class of bioactive plant‐derived compounds with significant pharmaceutical potential. These alkaloids are formed through oxidative cyclization of geissoschizine, catalyzed by homologous cytochrome P450 monooxygenases (CYP) known as sarpagan bridge enzymes (SBEs) and rhazimal ...
Mann SGA +6 more
europepmc +2 more sources
Natural Product Communications, 2018 Vallesiachotamine and isovallesiachotamine are pharmacologically active monoterpene indole alkaloids produced by Catharanthus roseus . However, the biosynthetic pathway for these two alkaloids has not been characterized.
Jianhua Zhu +6 more
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Virtual Screening of Alkaloid and Terpenoid Inhibitors of SMT Expressed in Naegleria sp.
Molecules, 2022 The pathogenic form of thermophilic Naegleria sp. i.e., Naegleria fowleri, also known as brain eating amoeba, causes primary amoebic encephalitis (PAM) with a >97% fatality rate.
Jason Abraham, Neha Chauhan, Supriyo Ray
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