Results 21 to 30 of about 16,226 (208)
Introduction Inflammatory bowel disease (IBD) includes ulcerative colitis (UC) and Crohn’s disease (CD). Genetic susceptibility together with environmental factors disturbs intestinal homeostasis, resulting in repeated and chronic inflammation with ...
Abeer A Mohamed +3 more
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Modulation of exogenous antibiotic activity by host cathelicidin LL‐37 [PDF]
Leszczyńska K, Namiot A, Janmey PA, Bucki R. Modulation of exogenous antibiotic activity by host cathelicidin LL‐37. APMIS 2010; 118: 830–6.The increasing number of infections caused by drug‐resistant bacteria has spurred efforts to develop new therapeutic strategies. When applied locally, exogenous antibiotics work in an environment rich in endogenous
Katarzyna, Leszczyńska +3 more
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Clostridioides difficile infection is currently the leading cause of nosocomial antibiotic-associated diarrhea and pseudomembranous colitis worldwide. Cathelicidins, a major group of natural antimicrobial peptides, have antimicrobial and immunomodulatory
Banglao Xu, Xianan Wu, Yi Gong, Ju Cao
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Pulmonary defense and the human cathelicidin hCAP-18/LL-37 [PDF]
Antimicrobial peptides form an important component of the innate immune system. The cathelicidin family, a key member of the antimicrobial peptide defenses, has been highly conserved throughout evolution. Though widespread in mammals, there is currently only one identified human example, hCAP-18/LL-37. The cathelicidins have been found to have multiple
Fahy, R. J., Wewers, M. D.
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BackgroundRosacea, a chronic inflammatory skin disorder etiologically associated with immune cells and the antibacterial peptide cathelicidin LL-37, can be effectively treated by oral carvedilol administration.ObjectiveTo investigate the molecular ...
Jiawen Zhang +11 more
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Antimicrobial peptides and eicosanoids : roles and interactions in inflammation and host defense [PDF]
Antimicrobial peptides (AMPs) have a broad spectrum of activities and exert their functions by both direct killing of microbes through the interaction with the microbial membrane, and modulation of innate and adaptive immunity of the host.
Tang, Xiao
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The Roles of Cathelicidin LL-37 in Inflammatory Bowel Disease [PDF]
Human cathelicidin LL-37, the only member of the cathelicidin family of host defense peptides expressed in humans, plays a crucial role in host defense against pathogen invasion, as well as in regulating the functions of anti-inflammation, antitumorigenesis, and tissue repair.
Lihua, Sun +3 more
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BackgroundTuberculosis remains a global threat and a public health problem that has eluded attempts to eradicate it. Low vitamin D levels have been identified as a risk factor for tuberculosis infection and disease.
Ester Lilian Acen +6 more
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Structural and functional analysis of the pro-domain of human cathelicidin, LL-37 [PDF]
Cathelicidins form a family of small host defense peptides distinct from another class of cationic antimicrobial peptides, the defensins. They are expressed as large precursor molecules with a highly conserved pro-domain known as the cathelin-like domain
Beckley, Amy J. +12 more
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Cathelicidin, vitamin D3 dan imunitas terhadap tuberkulosis
Abstrak. Tuberkulosis (TB) merupakan salah satu penyakit infeksi yang menjadi masalah di dunia. Risiko untuk mendapatkan infeksi TB dipengaruhi oleh imunitas alamiah melawan mikobakteria.
Yunita Arliny, Maryatun Hasan
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