Results 21 to 30 of about 16,226 (208)

Study of serum level of cathelicidin in patients with inflammatory bowel disease and its correlation to disease activity

open access: yesAl-Azhar Assiut Medical Journal, 2020
Introduction Inflammatory bowel disease (IBD) includes ulcerative colitis (UC) and Crohn’s disease (CD). Genetic susceptibility together with environmental factors disturbs intestinal homeostasis, resulting in repeated and chronic inflammation with ...
Abeer A Mohamed   +3 more
doaj   +1 more source

Modulation of exogenous antibiotic activity by host cathelicidin LL‐37 [PDF]

open access: yesAPMIS, 2010
Leszczyńska K, Namiot A, Janmey PA, Bucki R. Modulation of exogenous antibiotic activity by host cathelicidin LL‐37. APMIS 2010; 118: 830–6.The increasing number of infections caused by drug‐resistant bacteria has spurred efforts to develop new therapeutic strategies. When applied locally, exogenous antibiotics work in an environment rich in endogenous
Katarzyna, Leszczyńska   +3 more
openaire   +2 more sources

IL-27 induces LL-37/CRAMP expression from intestinal epithelial cells: implications for immunotherapy of Clostridioides difficile infection

open access: yesGut Microbes, 2021
Clostridioides difficile infection is currently the leading cause of nosocomial antibiotic-associated diarrhea and pseudomembranous colitis worldwide. Cathelicidins, a major group of natural antimicrobial peptides, have antimicrobial and immunomodulatory
Banglao Xu, Xianan Wu, Yi Gong, Ju Cao
doaj   +1 more source

Pulmonary defense and the human cathelicidin hCAP-18/LL-37 [PDF]

open access: yesImmunologic Research, 2005
Antimicrobial peptides form an important component of the innate immune system. The cathelicidin family, a key member of the antimicrobial peptide defenses, has been highly conserved throughout evolution. Though widespread in mammals, there is currently only one identified human example, hCAP-18/LL-37. The cathelicidins have been found to have multiple
Fahy, R. J., Wewers, M. D.
openaire   +2 more sources

A Novel Mechanism of Carvedilol Efficacy for Rosacea Treatment: Toll-Like Receptor 2 Inhibition in Macrophages

open access: yesFrontiers in Immunology, 2021
BackgroundRosacea, a chronic inflammatory skin disorder etiologically associated with immune cells and the antibacterial peptide cathelicidin LL-37, can be effectively treated by oral carvedilol administration.ObjectiveTo investigate the molecular ...
Jiawen Zhang   +11 more
doaj   +1 more source

Antimicrobial peptides and eicosanoids : roles and interactions in inflammation and host defense [PDF]

open access: yes, 2017
Antimicrobial peptides (AMPs) have a broad spectrum of activities and exert their functions by both direct killing of microbes through the interaction with the microbial membrane, and modulation of innate and adaptive immunity of the host.
Tang, Xiao
core   +1 more source

The Roles of Cathelicidin LL-37 in Inflammatory Bowel Disease [PDF]

open access: yesInflammatory Bowel Diseases, 2016
Human cathelicidin LL-37, the only member of the cathelicidin family of host defense peptides expressed in humans, plays a crucial role in host defense against pathogen invasion, as well as in regulating the functions of anti-inflammation, antitumorigenesis, and tissue repair.
Lihua, Sun   +3 more
openaire   +2 more sources

Impact of vitamin D status and cathelicidin antimicrobial peptide on adults with active pulmonary TB globally: A systematic review and meta-analysis.

open access: yesPLoS ONE, 2021
BackgroundTuberculosis remains a global threat and a public health problem that has eluded attempts to eradicate it. Low vitamin D levels have been identified as a risk factor for tuberculosis infection and disease.
Ester Lilian Acen   +6 more
doaj   +1 more source

Structural and functional analysis of the pro-domain of human cathelicidin, LL-37 [PDF]

open access: yes, 2013
Cathelicidins form a family of small host defense peptides distinct from another class of cationic antimicrobial peptides, the defensins. They are expressed as large precursor molecules with a highly conserved pro-domain known as the cathelin-like domain
Beckley, Amy J.   +12 more
core   +1 more source

Cathelicidin, vitamin D3 dan imunitas terhadap tuberkulosis

open access: yesJKS (Jurnal Kedokteran Syiah Kuala), 2020
Abstrak. Tuberkulosis (TB) merupakan salah satu penyakit infeksi yang menjadi masalah di dunia. Risiko untuk mendapatkan infeksi TB dipengaruhi oleh imunitas alamiah melawan mikobakteria.
Yunita Arliny, Maryatun Hasan
doaj   +1 more source

Home - About - Disclaimer - Privacy