Results 221 to 230 of about 102,381 (252)

Clinically relevant intra‐articular corticosteroid doses impair equine osteoclast function in vitro

Veterinary Surgery, EarlyView.
Abstract Objective To assess the effects of clinically relevant doses of commonly employed intra‐articular corticosteroids—specifically, triamcinolone acetonide (TCA), methylprednisolone acetate (MPA), and combination of betamethasone acetate and betamethasone sodium phosphate (BM)—on equine osteoclasts.
Gwladys Malek, Louis Kamus, Hélène Richard, Guy Beauchamp, Sheila Laverty   +4 more
wiley   +1 more source

Plant caspase-like proteins: from function identification to application in winter rapeseed genetic breeding. [PDF]

Front Plant Sci
Fan T, Fahim AM, Ma L, Liu L, Pu Y, Wang W, Sun W, Yang G, Wu J.   +8 more
europepmc   +1 more source

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source

Genetic and molecular evidence linking CTSH to Alzheimer's disease pathophysiology. [PDF]

Alzheimers Dement
Picard C, Aumont-Rodrigue G, Sarty I, Loncke J, Savard M, Maligne-Bruneau L, Poirier J, PREVENT‐AD research group.   +7 more
europepmc   +1 more source

Muscle wasting in cancer cachexia: Mechanisms and the role of exercise

Experimental Physiology, EarlyView.
Abstract Cancer cachexia (CC) is a multifactorial disease marked by a severe and progressive loss of lean muscle mass and characterized further by inflammation and a negative energy/protein balance, ultimately leading to muscle atrophy and loss of muscle tissue.
Zoe P. Libramento, Louisa Tichy, Traci L. Parry   +2 more
wiley   +1 more source

Nicotine and cotinine enhance SARS-CoV-2 entry through distinct but complementary mechanisms in human respiratory epithelial cells. [PDF]

J Virol
Xu J, Chan H-w, Yang R, Wu X-R, Malaviarachchi P, Wang H, Zhang X, Tang M-s.   +7 more
europepmc   +1 more source

Development and preclinical evaluation of selective vinyl sulfone-based probes for PET imaging of tumor-associated cathepsins. [PDF]

EJNMMI Radiopharm Chem
Cini O, Miranda A, Willocx D, Karakasidi A, Groot A, Moreira TDV, Leandro AP, Santos MMM, Moreira R, Elvas F.   +9 more
europepmc   +1 more source

RETRACTION: Mechanism of p27 Upregulation Induced by Downregulation of Cathepsin B and Upar in Glioma. [PDF]

Mol Oncol
europepmc   +1 more source

In Silico Docking and Spectroscopic Evaluation of a Thiocarbohydrazone Derivative: Structural Elucidation and Enzyme Inhibitory Mechanisms. [PDF]

Pharmaceuticals (Basel)
Karatzia M, Georgiou N, Apostolou EV, Papamichalis E, Hayes SC, Mavromoustakos T, Tzeli D.   +6 more
europepmc   +1 more source

Do collagen membranes with different thickness-related mechanical properties affect the outcomes of lateral bone augmentation? An immunohistochemical analysis. [PDF]

Clin Oral Investig
Lee D, Ko YC, Koo KT, Seol YJ, Kwon O, Lee YM, Lee J.   +6 more
europepmc   +1 more source