Results 31 to 40 of about 11,881,546 (284)

Expression of Cathepsins B, D, and G in Extracranial Arterio-Venous Malformation

Frontiers in Surgery, 2021
Objectives: We have previously identified a population of cells that expressed stemness-associated markers in extracranial arterio-venous malformation (AVM) and demonstrated expression of cathepsins B, D, and G on embryonic stem cell (ESC)-like ...
Lauren Hansen, Helen D. Brasch, Erin Paterson, Josie Patel, Nicholas Bockett, Paul F. Davis, Swee T. Tan, Swee T. Tan, Swee T. Tan   +8 more
doaj   +1 more source

Epoxysuccinyl peptide-derived cathepsin B inhibitors: Modulating membrane permeability by conjugation with the C-terminal heptapeptide segment of penetratin [PDF]

, 2002
Schaschke N, Deluca D, Assfalg-Machleidt I, Hohneke C, Sommerhoff CP, Machleidt W. Epoxysuccinyl peptide-derived cathepsin B inhibitors: Modulating membrane permeability by conjugation with the C-terminal heptapeptide segment of penetratin.
Schaschke, Norbert, Assfalg-Machleidt, Irmgard, Schaschke, N., Deluca, D, Sommerhoff, C. P., Höhneke, C., Sommerhoff, CP, Machleidt, W., Assfalg-Machleidt, I, Machleidt, Werner, Deluca, D., Deluca, Dominga, Sommerhoff, Christian P., Assfalg-Machleidt, I., Hohneke, C, Höhneke, Clara, Machleidt, W   +16 more
core   +1 more source

Cathepsin G, a Neutrophil Protease, Induces Compact Cell-Cell Adhesion in MCF-7 Human Breast Cancer Cells

Mediators of Inflammation, 2009
Cathepsin G is a serine protease secreted by activated neutrophils that play a role in the inflammatory response. Because neutrophils are known to be invading leukocytes in various tumors, their products may influence the characteristics of tumor cells ...
Tomoya Kudo, Hideaki Kigoshi, Takashi Hagiwara, Takahisa Takino, Masatoshi Yamazaki, Satoru Yui   +5 more
doaj   +1 more source

Expression of Cathepsins B, D, and G in WHO Grade I Meningioma

Frontiers in Surgery, 2019
Aim: We have recently demonstrated the presence of putative tumor stem cells (TSCs) in World Health Organization (WHO) grade I meningioma (MG) localized to the microvessels, which expresses components of the renin-angiotensin system (RAS).
Rosanna M. A. Rahman, Rosanna M. A. Rahman, Bede van Schaijik, Helen D. Brasch, Reginald W. Marsh, Reginald W. Marsh, Agadha C. Wickremesekera, Agadha C. Wickremesekera, Reuben Johnson, Kelvin Woon, Swee T. Tan, Swee T. Tan, Tinte Itinteang   +12 more
doaj   +1 more source

Peptide synthesis by recombinant Fasciola hepatica cathepsin L1 [PDF]

, 2006
Synthesis of the tripeptide Z-Phe-Arg-SerNH2 has been accomplished by a recombinant cysteine protease, cathepsin L1 from liver fluke (Fasciola hepatica), using Z-Phe-Arg-OMe as acyl acceptor and SerNH2 as nucleophile in 0.1 M ammonium acetate pH 9.0–12.5%
Ruth, Deborah M., Ó Fágáin, Ciarán, McMahon, Gillian   +2 more
core   +1 more source

Neutrophil Cathepsin G, but Not Elastase, Induces Aggregation of MCF-7 Mammary Carcinoma Cells by a Protease Activity-Dependent Cell-Oriented Mechanism

Mediators of Inflammation, 2014
We previously found that a neutrophil serine protease, cathepsin G, weakens adherence to culture substrates and induces E-cadherin-dependent aggregation of MCF-7 human breast cancer cells through its protease activity.
Satoru Yui, Yuuki Osawa, Takeo Ichisugi, Riyo Morimoto-Kamata   +3 more
doaj   +1 more source

Antigonococcal activity of human neutrophil cathepsin G [PDF]

Infection and Immunity, 1986
We have shown that lysosomal cathepsin G, prepared from acid extracts of granules derived from human polymorphonuclear granulocytes, exhibits potent in vitro antimicrobial activity against Neisseria gonorrhoeae. An isolated isozyme of cathepsin G was found to exhibit antigonococcal activity by a nonenzymatic mechanism in a time-dependent manner ...
W M, Shafer, V C, Onunka, L E, Martin
openaire   +2 more sources

Expression of Cathepsins B, D, and G in Isocitrate Dehydrogenase-Wildtype Glioblastoma

Frontiers in Surgery, 2017
AimTo investigate the expression of cathepsins B, D, and G, in relation to the cancer stem cell (CSC) subpopulations, we have previously characterized within isocitrate dehydogenase (IDH)-wildtype glioblastoma (IDHWGB).Methods3,3-Diaminobezidine (DAB ...
Sabrina P. Koh, Agadha C. Wickremesekera, Agadha C. Wickremesekera, Helen D. Brasch, Reginald Marsh, Swee T. Tan, Swee T. Tan, Tinte Itinteang   +7 more
doaj   +1 more source

Protective Effects of Ginger (Zingiber officinale) Extract against Diabetes-Induced Heart Abnormality in Rats [PDF]

Diabetes & Metabolism Journal, 2016
BackgroundDiabetic cardiomyopathy is an important causal factor in morbidity and mortality among diabetic patients, and currently, no effective means are available to reverse its pathological progress.
Behrouz Ilkhanizadeh, Alireza Shirpoor, Mohamad hasan Khadem Ansari, Samira Nemati, Yusef Rasmi   +4 more
doaj   +1 more source

Cathepsin-L can resist lysis by human serum in Trypanosoma brucei brucei. [PDF]

, 2014
Closely related African trypanosomes cause lethal diseases but display distinct host ranges. Specifically, Trypanosoma brucei brucei causes nagana in livestock but fails to infect humans, while Trypanosoma brucei gambiense and Trypanosoma brucei ...
Currier, Rachel B., Taane G Clark, Horn, David, José Afonso Guerra-Assunção, Clark, Taane G., Sam Alsford, Taane G. Clark (106263), David Horn (24969), Alsford, Sam, Rachel B Currier, Rachel B. Currier (144838), Guerra-Assunção, José Afonso, Currier, Rachel B, Horn, David; id_orcid, José Afonso Guerra-Assunção (166779), Guerra-Assunção, Jose Alfonso, Sam Alsford (24967), David Horn, Clark, Taane G   +18 more
core   +1 more source