Anti Cathepsin Antibody In Systemic Lupus Erythematosus
Antineutrophil cytoplasmic autoantibodies (ANCA) were found in patients with systemic lupus erythematosus (SLE). Cathepsin G was the major target antigen.
Nahla ghanim Abdul–majeed +2 more
doaj +1 more source
Targeting cathepsin G in myeloid leukemia [PDF]
Cathepsin G (CG) is a serine protease normally found within the azurophil granules of neutrophils. CG is expressed during the early stages of normal myeloid differentiation and-aberrantly-by myeloid leukemia cells. We have recently identified CG-derived HLA-A*0201-binding peptides that constitute promising targets for the immunotherapy of myeloid ...
openaire +2 more sources
Listericidal activity of human neutrophil cathepsin G [PDF]
We demonstrate that cathepsin G, derived from human neutrophils, exhibits potent in vitro antimicrobial activity against Listeria monocytogenes. Cathepsin G listericidal activity was by a non-enzymic mechanism and was dependent on the cationic nature of the molecule.
C E, Alford, E, Amaral, P A, Campbell
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Antibodies to selected minor target anti-neutrophil cytoplasmic antigens in systemic lupus patients
Background: Anti-neutrophil cytoplasmic antibodies (ANCA)minor subsets (elastase , lysozyme , cathepsin G , lactoferrin & BPI )are detected among systemic lupus erythromatus patients causing vasculitis.
Nahla G. abdul-Majeed
doaj +1 more source
The role and mechanism of cathepsin G in dermatomyositis
Dermatomyositis (DM) is an idiopathic inflammatory myopathy characterized by CD4+ T cells and B cells infiltration in perivascular and muscle tissue. Although the infiltration of inflammatory cells plays a key role in muscle damage, the exact mechanism is not clear.
Siming, Gao +5 more
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Identification of proteases employed by dendritic cells in the processing of protein purified derivative (PPD) [PDF]
Dendritic cells (DC) are known to present exogenous protein Ag effectively to T cells. In this study we sought to identify the proteases that DC employ during antigen processing.
Mansour Mohamadzadeh +9 more
core +1 more source
Expression of Cathepsins B, D, and G in Infantile Hemangioma [PDF]
The role of the renin-angiotensin system (RAS) in the biology of infantile hemangioma (IH) represents an emerging paradigm, particularly the involvement of renin, angiotensin converting enzyme, and angiotensin II. This study investigated the expression of cathepsins B, D, and G, enzymes that may modulate the RAS, in IH.The expression of cathepsins B, D,
Tinte eItinteang +6 more
openaire +3 more sources
Cloning of a cDNA encoding Schistosoma mansoni cathepsin C and expression in the yeast Pichia pastoris [PDF]
The cDNA encoding the proenzyme of cathepsin C from the parasitic helminth Schistosoma mansoni was amplified from a cDNA library using 5’ and 3’ specific primers containing sites for SnaBI and Avrll digestion.
Carty, Charlene
core +2 more sources
Prevalence and clinical significance of cathepsin G antibodies in systemic sclerosis
Objectives: To evaluate the prevalence and clinical significance of cathepsin G antibodies in patients affected with systemic sclerosis (SSc, scleroderma).
P. Grypiotis +7 more
doaj +1 more source
Polymorphisms of candidate genes associated with feed efficiency and growth traits in commercial crossbred pigs [PDF]
Feed efficiency is an important trait in the swine industry, but it is difficult to measure individually for genetic improvement. A total of 184 commercial pigs (50% Duroc, 25% Large White, and 25% Landrace) were collected for blood and genotyped.
Wootichai Kenchaiwong +2 more
doaj +1 more source

