Results 101 to 110 of about 44,977 (257)
Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components
Small Methods, EarlyView.The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu +6 more
wiley +1 more source
A new regulator of caveolae signalling
eLife, 2013 Cavin-3 regulates metabolism and cell proliferation by coordinating the activities of growth factor signalling cascades.
openaire +4 more sources
Up-regulation of Caveolae and Caveolar Constituents in Multidrug-resistant Cancer Cells [PDF]
, 1998 Yaakov Lavie +2 more
openalex +1 more source
Nanotechnology and cell death: Revolutionizing disease treatment with nanoparticle strategies
VIEW, EarlyView.Traditional disease treatments often face issues such as poor drug targeting and significant side effects, with many complex diseases lacking effective therapies. Our research utilizes tiny nanomaterials to treat diseases by regulating natural cell death processes, improving the immune environment, etc., enabling drugs to act more precisely.
Yiwen Wan +6 more
wiley +1 more source
Interactions between proteins bound to biomembranes
, 2003 We study a physical model for the interaction between general inclusions bound to fluid membranes that possess finite tension, as well as the usual bending rigidity. We are motivated by an interest in proteins bound to cell membranes that apply forces to
A. Albersdorfer +39 more
core +1 more source
Phosphatidylinositol 4-Phosphate Synthesis in Immunoisolated Caveolae-like Vesicles and Low Buoyant Density Non-caveolar Membranes [PDF]
, 1998 Mark G. Waugh +3 more
openalex +1 more source
X-Ray Spectrometry, EarlyView.ABSTRACT The study of the cytotoxic effects of gold nanoparticles (AuNP) is an active area of research. However, there is a lack of consistency in results with measures of cellular uptake relying on inductively coupled plasma (ICP)‐based methods, which introduce inconsistencies with sample preparation.
Natasha Hedden +5 more
wiley +1 more source
TNF-α-Mediated Apoptosis Is Initiated in Caveolae-Like Domains [PDF]
, 1999 Young‐Gyu Ko +4 more
openalex +1 more source
PTRF Confers Melanoma‐Acquired Drug Resistance Through the Upregulation of EGFR
Cell Proliferation, EarlyView.The upregulation of PTRF, a critical caveolar component, and the concomitant increase in caveolae number potentiate cellular proliferation and survival pathways, thereby contributing to melanoma drug resistance. ABSTRACT Melanoma is the most serious type of skin cancer. About half of all melanomas have activating BRAF mutations.
Miao Wang +11 more
wiley +1 more source
The urokinase-type plasminogen activator receptor, a GPI-linked protein, is localized in caveolae. [PDF]
, 1995 Andreas Stahl, Barbara M. Mueller
openalex +1 more source